Search Results - "Roelofsen, Thijs"

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study by Eerkens, Anneke L., Brummel, Koen, Vledder, Annegé, Paijens, Sterre T., Requesens, Marta, Loiero, Dominik, van Rooij, Nienke, Plat, Annechien, Haan, Floris-Jan, Klok, Patty, Yigit, Refika, Roelofsen, Thijs, de Lange, Natascha M., Klomp, Rie, Church, David, ter Elst, Arja, Wardenaar, René, Spierings, Diana, Foijer, Floris, Koelzer, Viktor Hendrik, Bosse, Tjalling, Bart, Joost, Jalving, Mathilde, Reyners, Anna K. L., de Bruyn, Marco, Nijman, Hans W.

“…Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in…”
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Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation carriers and controls by Mingels, Marjanka J.J.M, Roelofsen, Thijs, van der Laak, Jeroen A.W.M, de Hullu, Joanne A, van Ham, Maaike A.P.C, Massuger, Leon F.A.G, Bulten, Johan, Bol, Mijke

“…Abstract Objective A precursor lesion for ovarian carcinoma, tubal intraepithelial carcinoma (TIC), has been identified in BRCA-mutation carriers undergoing…”
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Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice by Nierkens, Stefan, den Brok, Martijn H, Roelofsen, Thijs, Wagenaars, Jori A L, Figdor, Carl G, Ruers, Theo J, Adema, Gosse J

“…The TLR9 agonist CpG is increasingly applied in preclinical and clinical studies as a therapeutic modality to enhance tumor immunity. The clinical application…”
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Spontaneous Regression of Ovarian Carcinoma After Septic Peritonitis; A Unique Case Report by Roelofsen, Thijs, Wefers, Christina, Gorris, Mark A J, Textor, Johannes C, Massuger, Leon F A G, de Vries, I Jolanda M, van Altena, Anne M

“…Despite advances in therapy, ovarian cancer remains the most lethal gynecological malignancy and prognosis has not substantially improved over the past 3…”
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B cells critical for outcome in high grade serous ovarian carcinoma by Vledder, Annegé, Paijens, Sterre T., Loiero, Dominik, Maagdenberg, Alexis, Duiker, Evelien W., Bart, Joost, Hendriks, Anne M., Jalving, Mathilde, Werner, Naomi, Rooij, Nienke, Plat, Annechien, Wisman, G. Bea A., Yigit, Refika, Roelofsen, Thijs, Kruse, Arnold J., Lange, Nastascha M., Koelzer, Viktor H., Bruyn, Marco, Nijman, Hans W.

“…Recent work has shown evidence for the prognostic significance of tumor infiltrating B cells (B‐TIL) in high grade serous ovarian carcinoma (HGSOC), the…”
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Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study by Eerkens, Anneke L., Brummel, Koen, Vledder, Annegé, Paijens, Sterre T., Requesens, Marta, Loiero, Dominik, van Rooij, Nienke, Plat, Annechien, Haan, Floris-Jan, Klok, Patty, Yigit, Refika, Roelofsen, Thijs, de Lange, Natascha M., Klomp, Rie, Church, David, ter Elst, Arja, Wardenaar, René, Spierings, Diana, Foijer, Floris, Koelzer, Viktor Hendrik, Bosse, Tjalling, Bart, Joost, Jalving, Mathilde, Reyners, Anna K. L., de Bruyn, Marco, Nijman, Hans W.

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The origin of serous ovarian cancer may be found in the uterus: A novel hypothesis by Massuger, Leon, Roelofsen, Thijs, Ham, Maaike van, Bulten, Johan

“…Summary Since 1971 the incessant ovulation theory by Fathalla is widely accepted as theory for ovarian carcinogenesis, supported mainly by epidemiological…”
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Pure Compared With Mixed Serous Endometrial Carcinoma: Two Different Entities? by ROELOFSEN, Thijs, VAN HAM, Maaike A. P. C, WIERSMA VAN TILBURG, Johanna M, ZOMER, Saskia F, BOL, Mijke, MASSUGER, Leon F. A. G, BULTEN, Johan

“…To analyze whether mixed compared with pure uterine papillary serous carcinoma histology affects clinical outcome, and to assess uterine papillary serous…”
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Histone modification patterns associated with the human X chromosome by Brinkman, Arie B, Roelofsen, Thijs, Pennings, Sebastiaan W C, Martens, Joost H A, Jenuwein, Thomas, Stunnenberg, Hendrik G

“…X inactivation is associated with chromosome‐wide establishment of inactive chromatin. Although this is classically regarded as facultative heterochromatin…”
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Clinical management of uterine papillary serous carcinoma by Roelofsen, Thijs, van Ham, Maaike A, de Hullu, Joanne A, Massuger, Leon F

“…Uterine papillary serous carcinoma (UPSC) is an aggressive variant of endometrial cancer. Owing to its rarity, most clinicians are unfamiliar with the clinical…”
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Concurrent endometrial intraepithelial carcinoma (EIC) and serous ovarian cancer: can EIC be seen as the precursor lesion? by Roelofsen, Thijs, van Kempen, Léon C L T, van der Laak, Jeroen A W M, van Ham, Maaike A, Bulten, Johan, Massuger, Leon F A G

“…The pathogenesis of serous ovarian carcinoma (SOC) is still unknown. Recently, endometrial intraepithelial carcinoma (EIC) was proposed to be the precursor…”
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Cervical Cytology in Serous and Endometrioid Endometrial Cancer by Roelofsen, Thijs, Geels, Yvette P, Pijnenborg, Johanna M.A, van Ham, Maaike A.P.C, Zomer, Saskia F, van Tilburg, Johanna M Wiersma, Snijders, Marc P.M.L, Siebers, Albert G, Bulten, Johan, Massuger, Leon F.A.G

“…The aim of this study was to determine the frequency of abnormal cervical cytology in preoperative cervical cytology of patients diagnosed with uterine…”
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Preoperative CA-125 predicts extra-uterine disease and survival in uterine papillary serous carcinoma patients by Roelofsen, Thijs, Mingels, Marjanka, Hendriks, Jan C.M., Samlal, Rahul A., Snijders, Marc P., Aalders, Anette L., Bulten, Johan, Van Ham, Maaike A.P.C., Massuger, Leon F.A.G.

“…Objective We determined the clinical utility of preoperative serum CA-125 as predictor of extra-uterine disease and as prognosticator for survival in patients…”
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Spontaneous Regression of Ovarian Carcinoma After Septic Peritonitis; A Unique Case Report by Roelofsen, Thijs, Wefers, Christina, Gorris, Mark A J, Textor, Johannes C, Massuger, Leon F A G, de Vries, I Jolanda M, van Altena, Anne M

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