Search Results - "Roelofs, Rian"

Towards the human colorectal cancer microbiome by Marchesi, Julian R, Dutilh, Bas E, Hall, Neil, Peters, Wilbert H M, Roelofs, Rian, Boleij, Annemarie, Tjalsma, Harold

“…Multiple factors drive the progression from healthy mucosa towards sporadic colorectal carcinomas and accumulating evidence associates intestinal bacteria with…”
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Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone by Diepeveen, Laura, Roelofs, Rian, Grebenchtchikov, Nicolai, van Swelm, Rachel, Kautz, Leon, Swinkels, Dorine

“…Erythroferrone (ERFE), the erythroid regulator of iron metabolism, inhibits hepcidin to increase iron availability for erythropoiesis. ERFE plays a…”
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Kidney tubule iron loading in experimental focal segmental glomerulosclerosis by van Swelm, Rachel P. L., Beurskens, Sanne, Dijkman, Henry, Wiegerinck, Erwin T. G., Roelofs, Rian, Thévenod, Frank, van der Vlag, Johan, Wetzels, Jack F. M., Swinkels, Dorine W., Smeets, Bart

“…Kidney iron deposition may play a role in the progression of tubulointerstitial injury during chronic kidney disease. Here, we studied the molecular mechanisms…”
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Iron-Induced Virulence of Salmonella enterica Serovar Typhimurium at the Intestinal Epithelial Interface Can Be Suppressed by Carvacrol by KORTMAN, Guus A. M, ROELOFS, Rian W. H. M, SWINKELS, Dorine W, DE JONGE, Marien I, BURT, Sara A, TJALSMA, Harold

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes by de Kok, Jacques B, Roelofs, Rian W, Giesendorf, Belinda A, Pennings, Jeroen L, Waas, Erwin T, Feuth, Ton, Swinkels, Dorine W, Span, Paul N

“…For interpretation of quantitative gene expression measurements in clinical tumor samples, a normalizer is necessary to correct expression data for differences…”
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Streptococcus gallolyticus Increases Expression and Activity of Aryl Hydrocarbon Receptor-Dependent CYP1 Biotransformation Capacity in Colorectal Epithelial Cells by Taddese, Rahwa, Roelofs, Rian, Draper, Derk, Wu, Xinqun, Wu, Shaoguang, Swinkels, Dorine W, Tjalsma, Harold, Boleij, Annemarie

“…The opportunistic pathogen is one of the few intestinal bacteria that has been consistently linked to colorectal cancer (CRC). This study aimed to identify…”
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Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury by Diepeveen, Laura E, Stegemann, Gaby, Wiegerinck, Erwin T, Roelofs, Rian, Naber, Myrthe, Lóreal, Olivier, Smeets, Bart, Thévenod, Frank, Swinkels, Dorine W, van Swelm, Rachel P L

“…Hemolysis is known to cause acute kidney injury (AKI). The iron regulatory hormone hepcidin, produced by renal distal tubules, is suggested to exert a…”
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Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food‐borne bacterial pathogens by Kortman, Guus A. M., Mulder, Michelle L. M., Richters, Thijs J. W., Shanmugam, Nanda K. N., Trebicka, Estela, Boekhorst, Jos, Timmerman, Harro M., Roelofs, Rian, Wiegerinck, Erwin T., Laarakkers, Coby M., Swinkels, Dorine W., Bolhuis, Albert, Cherayil, Bobby J., Tjalsma, Harold

“…Orally administrated iron is suspected to increase susceptibility to enteric infections among children in infection endemic regions. Here we investigated the…”
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EPO and hepcidin plasma concentrations in blood donors and β‐thalassemia intermedia are not related to commercially tested plasma ERFE concentrations by Schotten, Nienke, Laarakkers, Coby M. M., Roelofs, Rian W., Origa, Raffaella, van Kraaij, Marian G. J., Swinkels, Dorine W.

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DD3(PCA3), a very sensitive and specific marker to detect prostate tumors by de Kok, Jacques B, Verhaegh, Gerald W, Roelofs, Rian W, Hessels, Daphne, Kiemeney, Lambertus A, Aalders, Tilly W, Swinkels, Dorine W, Schalken, Jack A

“…We identified DD3(PCA3) as one of the most prostate cancer-specific genes at present (M. J. Bussemakers et al. Cancer Res., 59: 5975-5979, 1999). Consequently,…”
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No replicating evidence for anti‐amyloid‐β autoantibodies in cerebral amyloid angiopathy‐related inflammation by Berg, Emma, Roelofs, Rian, Jäkel, Lieke, Greenberg, Steven M., Charidimou, Andreas, Etten, Ellis S., Boche, Delphine, Klijn, Catharina J. M., Schreuder, Floris H. B. M., Kuiperij, H. Bea, Verbeek, Marcel M.

“…Objective Elevated levels of anti‐amyloid‐β (anti‐Aβ) autoantibodies in cerebrospinal fluid (CSF) have been proposed as a diagnostic biomarker for cerebral…”
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PCR-restriction fragment length polymorphism method to detect the X/Y polymorphism in the promoter site of the mannose-binding lectin gene by Roelofs, Rian W, Sprong, Tom, de Kok, Jacques B, Swinkels, Dorine W

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The Prognostic Role of the STK15 T91A Polymorphism and of STK15 mRNA Expression in Patients with Urothelial Cell Carcinoma by SCHULTZ, Iman J, KIEMENEY, Lambertus A, ROELOFS, Rian, VAN AARSSEN, Yvonne, BABJUK, Marko, WILLEMS, Johannes L, MALMSTRÖM, Per-Uno, SWINKELS, Dorine W, WITJES, J. Alfred, DE KOK, Jacques B

“…Background: The prognostic role of the STK15 T91A polymorphism and of STK15 mRNA expression was investigated in patients with urothelial cell carcinoma (UCC)…”
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Erythropoiesis-hepcidin-iron axis in patients with X-linked sideroblastic anaemia: An explorative biomarker study by Hoving, Vera, Nijssen, Lieke E, Donker, Albertine E, Roelofs, Rian, Schols, Saskia E M, Swinkels, Dorine W

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Quantification of hTERT mRNA and telomerase activity in bladder washings of patients with recurrent urothelial cell carcinomas by DE KOK, Jacques B, VAN BALKEN, Michael R, ROELOFS, Rian W. H. M, VAN AARSSEN, Yvonne A. W. G, SWINKELS, Dorine W, GUNNEWIEK, Jacqueline M. T. Klein

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Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome by Hoeks, Marlijn, Bagguley, Tim, van Marrewijk, Corine, Smith, Alex, Bowen, David, Culligan, Dominic, Kolade, Seye, Symeonidis, Argiris, Garelius, Hege, Spanoudakis, Michail, Langemeijer, Saskia, Roelofs, Rian, Wiegerinck, Erwin, Tatic, Aurelia, Killick, Sally, Panagiotidis, Panagiotis, Stanca, Oana, Hellström-Lindberg, Eva, Cermak, Jaroslav, van der Klauw, Melanie, Wouters, Hanneke, van Kraaij, Marian, Blijlevens, Nicole, Swinkels, Dorine W., de Witte, Theo

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Selective antibody response to Streptococcus gallolyticus pilus proteins in colorectal cancer patients by Boleij, Annemarie, Roelofs, Rian, Danne, Camille, Bellais, Samuel, Dramsi, Shaynoor, Kato, Ikuko, Tjalsma, Harold

“…Streptococcus gallolyticus subsp. gallolyticus (previously called Streptococcus bovis biotype I) infections have long been associated with colorectal cancer…”
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Bacterial Responses to a Simulated Colon Tumor Microenvironment by Boleij, Annemarie, Dutilh, Bas E., Kortman, Guus A.M., Roelofs, Rian, Laarakkers, Coby M., Engelke, Udo F., Tjalsma, Harold

“…One of the few bacteria that have been consistently linked to colorectal cancer (CRC) is the opportunistic pathogen Streptococcus gallolyticus. Infections with…”
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EPO and hepcidin plasma concentrations in blood donors and [beta]-thalassemia intermedia are not related to commercially tested plasma ERFE concentrations by Schotten, Nienke, Laarakkers, Coby M M, Roelofs, Rian W, Origa, Raffaella, van Kraaij, Marian G J, Swinkels, Dorine W

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Partial Associations of Dietary Iron, Smoking and Intestinal Bacteria with Colorectal Cancer Risk by Kato, Ikuko, Boleij, Annemarie, Kortman, Guus A. M, Roelofs, Rian, Djuric, Zora, Severson, Richard K, Tjalsma, Harold

“…Smoking and high red meat intake have been associated with colorectal cancer (CRC) risk. Increased iron exposure may be a common factor, favoring the…”
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