Search Results - "Roelofs, H. M. J."

Long-term olive oil-based parenteral nutrition sustains innate immune function in home patients without active underlying disease by Olthof, E.D, Roelofs, H.M.J, Versleijen, M.W.J, te Morsche, R.H.M, Simonetti, E.R, Hermans, P.W.M, Wanten, G.J.A

“…Summary Background & aims It remains unclear whether impaired host defenses contribute to the increased risk for infectious complications seen in patients on…”
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Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis by Berkhout, M., Roelofs, H. M. J., te Morsche, R. H. M., Dekker, E., van Krieken, J. H. J. M., Nagengast, F. M., Peters, W. H. M.

“…Background: Patients with familial adenomatous polyposis (FAP) are at high risk of developing duodenal adenomas and carcinomas. Besides germline mutations in…”
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Genetic polymorphism in UDP-glucuronosyltransferase 2B7 and colorectal cancer risk by van der Logt, E M J, te Morsche, R H M, Groenendaal, N, Roelofs, H M J, de Metz, M, van der Stappen, J W, Nagengast, F M, Peters, W H M

“…Colorectal cancer (CRC) is one of the most common malignancies in the Western world. CRC is strongly associated with lifestyle factors. Susceptibility to CRC…”
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Deficient UDP‐glucuronosyltransferase detoxification enzyme activity in the small intestinal mucosa of patients with coeliac disease by GOERRES, M., ROELOFS, H. M. J., JANSEN, J. B. M. J., PETERS, W. H. M.

“…Summary Background  Small intestinal malignancies in humans are rare; however, patients with coeliac disease have a relatively high risk for such tumours…”
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Decreased levels of mucosal detoxification enzymes in the pouch of patients with familial adenomatous polyposis by Friederich, P., Berkhout, M., Roelofs, H. M. J., van Goor, H., van Krieken, J. H. J. M., Peters, W. H. M., Nagengast, F. M.

“…Background: Adenomas can develop in the pouch after colectomy with ileal pouch–anal anastomosis (IPAA) in patients with familial adenomatous polyposis (FAP)…”
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Detoxification enzymes in the duodenal mucosa of patients with familial adenomatous polyposis by Berkhout, M., Roelofs, H. M. J., Friederich, P., van Krieken, J. H. J. M., Nagengast, F. M., Peters, W. H. M.

“…Unlikely to be involved in duodenal polyposis…”
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Induction of rat hepatic and intestinal UDP-glucuronosyltransferases by naturally occurring dietary anticarcinogens by van der Logt, E.M.J., Roelofs, H.M.J., Nagengast, F.M., Peters, W.H.M.

“…Gastrointestinal tumours are among the most common malignancies in Western society, the majority of which are associated with dietary and lifestyle factors…”
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Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk by van der Logt, E.M.J., Bergevoet, S.M., Roelofs, H.M.J., van Hooijdonk, Z., te Morsche, R.H.M., Wobbes, T., de Kok, J.B., Nagengast, F.M., Peters, W.H.M.

“…Colorectal cancer (CRC) is one of the most common malignancies in the Western world showing an increasing incidence, and has been associated with genetic and…”
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Expression of the glutathione enzyme system of human colon mucosa by localisation, gender and age by Hoensch, H., Peters, W. H. M., Roelofs, H. M. J., Kirch, W.

“…ABSTRACT Background: The glutathione S-transferases (GST) can metabolise endogenous and exogenous toxins and carcinogens by catalysing the conjugation of…”
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Influence of clinical factors, diet, and drugs on the human upper gastrointestinal glutathione system by Hoensch, H, Morgenstern, I, Petereit, G, Siepmann, M, Peters, W H M, Roelofs, H M J, Kirch, W

“…Background: Glutathione (GSH) and the cytosolic glutathione S-transferases (GSTs) protect the gastrointestinal mucosa against the toxic effects of a wide…”
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Genetic polymorphisms in biotransformation enzymes in Crohn’s disease: association with microsomal epoxide hydrolase by de Jong, D J, van der Logt, E M J, van Schaik, A, Roelofs, H M J, Peters, W H M, Naber, T H J

“…Background: Mucosal biotransformation enzymes can modify toxic compounds in the gut. As chemical or oxidative stress may be involved in the aetiology of…”
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Glutathione peroxidases in human head and neck cancer by Mulder, T P, Manni, J J, Roelofs, H M, Peters, W H, Wiersma, A

“…Glutathione peroxidases (GPX), enzymes that catalyze the reduction of reactive intermediates have been implicated in the action of several cytostatic drugs…”
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Influence of ethanol induction on the metabolic activation of genotoxic agents by isolated rat hepatocytes by NEIS, J. M, TE BRÖMMELSTROET, B. W. J, VAN GEMERT, P. J. L, ROELOFS, H. M. J, HENDERSON, P. T

“…The effects of ethanol-feeding to rats, over a 6-week period, on the activation of genotoxic compounds of different chemical classes, requiring metabolic…”
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Microstructure statistics–property relations of silver particle-based interconnects by Gillman, A., Roelofs, M.J.G.H., Matouš, K., Kouznetsova, V.G., van der Sluis, O., van Maris, M.P.F.H.L.

“…[Display omitted] This paper presents a novel approach for establishing microstructure statistics-property relations for a silver particle-based thermal…”
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The capacity of hysterosalpingography and laparoscopy to predict natural conception by Verhoeve, H.R., Coppus, S.F.P.J., van der Steeg, J.W., Steures, P., Hompes, P.G.A., Bourdrez, P., Bossuyt, P.M.M., van der Veen, F., Mol, B.W.J.

“…BACKGROUND Laparoscopy has been claimed to be superior to hysterosalpingography (HSG) in predicting fertility. Whether this conclusion is applicable to a…”
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Protein Carbonyls in Decidua and Placenta of Pre-eclamptic Women as Markers for Oxidative Stress by Zusterzeel, P.L.M, Rütten, H, Roelofs, H.M.J, Peters, W.H.M, Steegers, E.A.P

“…Enhanced levels of reactive oxygen species (ROS) and decreased levels of antioxidants may contribute to the development of pre-eclampsia. Protein carbonyls may…”
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Polymorphic expression of the glutathione S-transferase P1 gene and its susceptibility to Barrett's esophagus and esophageal carcinoma by VAN LIESHOUT, E. M. M, ROELOFS, H. M. J, DEKKER, S, MULDER, C. J. J, WOBBES, T, JANSEN, J. B. M. J, PETERS, W. H. M

“…Factors determining individual susceptibility to esophageal cancer or premalignant Barrett's epithelium are still largely unclear. An imbalance between phase I…”
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No genetic association between EPHX1 and Crohn’s disease by Peters, W H M, van der Logt, E M J, te Morsche, R H M, Roelofs, H M J, de Jong, D J, Naber, T H J

“…The Tyr allele frequencies of 0.70 and 0.68 obtained for cases and controls, respectively, were very similar to the corresponding values of 0.71 and 0.70, as…”
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The antiandrogenic effect of progesterone on the hamster flank organ by Vermorken, A J, Goos, C M, Roelofs, H M

“…Progesterone, topically applied, prevents the stimulation of the hamster flank organ by testosterone, but not by dihydrotestosterone. 5…”
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Cyclic variations in glycoprotein synthesis in the columnar cells of the human cervix by Roelofs, H J, van Kooij, R J, Kramer, M F

“…The rate of glycoprotein synthesis by the columnar cells of the human endocervix was measured during one cycle in 12 women by autoradiography. An increase in…”
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