Search Results - "Roelandt, Truus"

Acute Acidification of Stratum Corneum Membrane Domains Using Polyhydroxyl Acids Improves Lipid Processing and Inhibits Degradation of Corneodesmosomes by Hachem, Jean-Pierre, Roelandt, Truus, Schürer, Nanna, Pu, Xu, Fluhr, Joachim, Giddelo, Christina, Man, Mao-Qiang, Crumrine, Debra, Roseeuw, Diane, Feingold, Kenneth R., Mauro, Theodora, Elias, Peter M.

“…Neutralization of the normally acidic stratum corneum (SC) has deleterious consequences for permeability barrier homeostasis and SC integrity/cohesion…”
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Basis for Enhanced Barrier Function of Pigmented Skin by Man, Mao-Qiang, Lin, Tzu-Kai, Santiago, Juan L., Celli, Anna, Zhong, Lily, Huang, Zhi-Ming, Roelandt, Truus, Hupe, Melanie, Sundberg, John P., Silva, Kathleen A., Crumrine, Debra, Martin-Ezquerra, Gemma, Trullas, Carles, Sun, Richard, Wakefield, Joan S., Wei, Maria L., Feingold, Kenneth R., Mauro, Theodora M., Elias, Peter M.

“…Humans with darkly pigmented skin display superior permeability barrier function in comparison with humans with lightly pigmented skin. The reduced pH of the…”
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Topical Antihistamines Display Potent Anti-Inflammatory Activity Linked in Part to Enhanced Permeability Barrier Function by Lin, Tzu-Kai, Man, Mao-Qiang, Santiago, Juan-Luis, Park, Kyungho, Roelandt, Truus, Oda, Yuko, Hupe, Melanie, Crumrine, Debra, Lee, Hae-Jin, Gschwandtner, Maria, Thyssen, Jacob P., Trullas, Carles, Tschachler, Erwin, Feingold, Kenneth R., Elias, Peter M.

“…Systemic antagonists of the histamine type 1 and 2 receptors (H1/2r) are widely used as anti-pruritics and central sedatives, but demonstrate only modest…”
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Serine Protease Signaling of Epidermal Permeability Barrier Homeostasis by Hachem, Jean-Pierre, Houben, Evi, Crumrine, Debra, Man, Mao-Quiang, Schurer, Nanna, Roelandt, Truus, Choi, Eung H., Uchida, Yoshikazu, Brown, Barbara E., Feingold, Kenneth R., Elias, Peter M.

“…Evidence is growing that protease-activated receptor-2 (PAR-2) plays a key role in epithelial inflammation. We hypothesized here that PAR-2 plays a central…”
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Proteolytically Active Allergens Cause Barrier Breakdown by Roelandt, Truus, Heughebaert, Carol, Hachem, Jean-Pierre

“…Two major allergens—the house dust mite Dermatophagoides pteronyssinus (Der p 1) and cockroach allergens—are proteolytically active and stimulate the…”
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Cannabinoid receptors 1 and 2 oppositely regulate epidermal permeability barrier status and differentiation by Roelandt, Truus, Heughebaert, Carol, Bredif, Stephanie, Giddelo, Christina, Baudouin, Caroline, Msika, Philippe, Roseeuw, Diane, Uchida, Yoshikazu, Elias, Peter M., Hachem, Jean-Pierre

“…Cannabinoid receptors (CBR) 1 and 2 have been implicated in keratinocyte differentiation/proliferation. How CB receptors affect epidermal permeability barrier…”
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Actin dynamics regulate immediate PAR-2-dependent responses to acute epidermal permeability barrier abrogation by Roelandt, Truus, Heughebaert, Carol, Verween, Gunther, Giddelo, Christina, Verbeken, Gilbert, Pirnay, Jean-Paul, Devos, Daniel, Crumrine, Debra, Roseeuw, Diane, Elias, Peter M, Hachem, Jean-Pierre

“…Abstract Background Lamellar body (LB) secretion and terminal differentiation of stratum granulosum (SG) cells are signaled by both protease activated…”
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Acute Modulations in Permeability Barrier Function Regulate Epidermal Cornification by Demerjian, Marianne, Hachem, Jean-Pierre, Tschachler, Erwin, Denecker, Geertrui, Declercq, Wim, Vandenabeele, Peter, Mauro, Theodora, Hupe, Melanie, Crumrine, Debra, Roelandt, Truus, Houben, Evi, Elias, Peter M, Feingold, Kenneth R

“…Stratum corneum comprises corneocytes, derived from outer stratum granulosum during terminal differentiation, embedded in a lipid-enriched extracellular…”
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Acute Modulations in Permeability Barrier Function Regulate Epidermal Cornification: Role of Caspase-14 and the Protease-Activated Receptor Type 2 by Demerjian, Marianne, Hachem, Jean-Pierre, Tschachler, Erwin, Denecker, Geertrui, Declercq, Wim, Vandenabeele, Peter, Mauro, Theodora, Hupe, Melanie, Crumrine, Debra, Roelandt, Truus, Houben, Evi, Elias, Peter M, Feingold, Kenneth R

“…Stratum corneum comprises corneocytes, derived from outer stratum granulosum during terminal differentiation, embedded in a lipid-enriched extracellular…”
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Cellular Changes that Accompany Shedding of Human Corneocytes by Lin, Tzu-Kai, Crumrine, Debra, Ackerman, Larry D., Santiago, Juan-Luis, Roelandt, Truus, Uchida, Yoshikazu, Hupe, Melanie, Fabriàs, Gemma, Abad, Jose L., Rice, Robert H., Elias, Peter M.

“…Corneocyte desquamation has been ascribed to the following: 1) proteolytic degradation of corneodesmosomes (CDs); 2) disorganization of extracellular lamellar…”
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The “Caveolae Brake Hypothesis” and the Epidermal Barrier by Roelandt, Truus, Giddelo, Christina, Heughebaert, Carol, Denecker, Geertrui, Hupe, Melanie, Crumrine, Debra, Kusuma, Andy, Haftek, Marek, Roseeuw, Diane, Declercq, Wim, Feingold, Kenneth R., Elias, Peter M., Hachem, Jean-Pierre

“…Epidermal permeability barrier formation depends upon lamellar body (LB) secretion/fusion with the apical plasma membrane (APM) of outermost stratum granulosum…”
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Restoration of tumor equilibrium after immunotherapy for advanced melanoma: three illustrative cases by Wilgenhof, Sofie, Pierret, Lauranne, Corthals, Jurgen, Van Nuffel, An M T, Heirman, Carlo, Roelandt, Truus, De Coninck, Arlette, Verfaillie, Guy, Vandenbroucke, Frederik, Van Riet, Ivan, Bonehill, Aude, Thielemans, Kris, Neyns, Bart

“…Metastatic melanoma runs a predictable detrimental course in the vast majority of patients. New modalities of immunotherapy, such as melanoma antigen-specific…”
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Lipid Rafts and Caveolae in the Terminal Differentiation of Epidermal Keratinocytes by Roelandt, Truus, Roseeuw, Diane, Giddelo, Christina, Hachem, Jean-Pierre

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Hemorrhagic regression of melanoma metastases during therapeutic vaccination: a report of three cases by Pierret, Lauranne, Baren, Nicolas Van, Bonehill, Aude, Corthals, Jurgen, Van Nuffel, An M T, Heirman, Carlo, Roelandt, Truus, De Coninck, Arlette, Riet, Ivan Van, Degreef, Ellen, Goossens, Annieta, Verfaillie, Guy, Roseeuw, Diane, Thielemans, Kris, Neyns, Bart

“…Melanoma metastases are characterized by pronounced neo-angiogenesis and spontaneous bleeding frequently occurring within central nervous system metastases…”
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Mite and Cockroach Allergens Activate Protease-Activated Receptor 2 and Delay Epidermal Permeability Barrier Recovery. Commentary by ROELANDT, Truus, HEUGHEBAERT, Carol, JEONG HEE HONG, DONG MIN SHIN, SEUNG HUN LEE, HACHEM, Jean-Pierre, SE KYOO JEONG, HYUN JEONG KIM, YOUM, Jong-Kyung, SUNG KU AHN, EUNG HO CHOI, MYUNG HYUN SOHN, KIM, Kyu-Earn

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