Search Results - "Roediger, Jan"
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Directional DBS increases side‐effect thresholds—A prospective, double‐blind trial
Published in Movement disorders (01-10-2017)“…ABSTRACT Objective The objective of this study was to investigate whether directional deep brain stimulation (DBS) of the subthalamic nucleus in Parkinson's…”
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Probabilistic sweet spots predict motor outcome for deep brain stimulation in Parkinson disease
Published in Annals of neurology (01-10-2019)“…Objective To investigate whether functional sweet spots of deep brain stimulation (DBS) in the subthalamic nucleus (STN) can predict motor improvement in…”
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A First Methodological Development and Validation of ReTap: An Open-Source UPDRS Finger Tapping Assessment Tool Based on Accelerometer-Data
Published in Sensors (Basel, Switzerland) (31-05-2023)“…Bradykinesia is a cardinal hallmark of Parkinson's disease (PD). Improvement in bradykinesia is an important signature of effective treatment. Finger tapping…”
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Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings
Published in NPJ Parkinson's Disease (19-04-2022)“…Adaptive deep brain stimulation (aDBS) is a promising concept for feedback-based neurostimulation, with the potential of clinical implementation with the…”
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Effect of subthalamic deep brain stimulation on posture in Parkinson's disease: A blind computerized analysis
Published in Parkinsonism & related disorders (01-05-2019)“…We sought to assess the effect of subthalamic deep brain stimulation (STN DBS) on Parkinson's disease (PD)-associated postural abnormalities. A computerized…”
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Lead-OR: A multimodal platform for deep brain stimulation surgery
Published in eLife (20-05-2022)“…Deep brain stimulation (DBS) electrode implant trajectories are stereotactically defined using preoperative neuroimaging. To validate the correct trajectory,…”
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Parameter selection drives electrophysiological responses to adaptive deep brain stimulation in Parkinson’s disease
Published in Brain stimulation (01-01-2023)Get full text
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Automated deep brain stimulation programming based on electrode location – a randomized, cross-over trial using a data-driven algorithm
Published in Brain stimulation (01-01-2023)Get full text
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Linking profiles of pathway activation with clinical motor improvements – A retrospective computational study
Published in NeuroImage clinical (01-01-2022)“…•Two cohorts undergoing deep brain stimulation for treatment of Parkinson’s Disease studied.•Patient-specific pathway activations estimated using advanced…”
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CLOVER-DBS: Algorithm-Guided Deep Brain Stimulation-Programming Based on External Sensor Feedback Evaluated in a Prospective, Randomized, Crossover, Double-Blind, Two-Center Study
Published in Journal of Parkinson's disease (01-01-2021)“…Recent technological advances in deep brain stimulation (DBS) (e.g., directional leads, multiple independent current sources) lead to increasing…”
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StimFit—A Data‐Driven Algorithm for Automated Deep Brain Stimulation Programming
Published in Movement disorders (01-03-2022)“…Background Finding the optimal deep brain stimulation (DBS) parameters from a multitude of possible combinations by trial and error is time consuming and…”
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Christmas‐Related Reduction in Beta Activity in Parkinson's Disease
Published in Movement disorders (01-04-2023)“…Background Subthalamic nucleus (STN) beta (13 ‐ 35 Hz) activity is a biomarker reflecting motor state in Parkinson's disease (PD). Adaptive deep brain…”
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Local Field Potentials Predict Motor Performance in Deep Brain Stimulation for Parkinson's Disease
Published in Movement disorders (01-12-2023)“…Background Deep brain stimulation (DBS) is an effective treatment option for patients with Parkinson's disease (PD). However, clinical programming remains…”
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Single threshold adaptive deep brain stimulation in Parkinson's disease depends on parameter selection, movement state and controllability of subthalamic beta activity
Published in Brain stimulation (01-01-2024)“…Deep brain stimulation (DBS) is an invasive treatment option for patients with Parkinson's disease. Recently, adaptive DBS (aDBS) systems have been developed,…”
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Automated deep brain stimulation programming based on electrode location: a randomised, crossover trial using a data-driven algorithm
Published in The Lancet. Digital health (01-02-2023)“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly effective in controlling motor symptoms in patients with Parkinson's disease. However,…”
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Acute Polyarthritis Associated With Active Epstein-Barr Virus Infection
Published in JAMA : the journal of the American Medical Association (10-12-1982)“…Nine patients with an initial onset of symptoms of acute arthritis within the preceding four weeks were enrolled in a prospective serological study with…”
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