Search Results - "Roe, D"

Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury by Li, Tao, Zhang, Zhen, Kolwicz, Stephen C., Abell, Lauren, Roe, Nathan D., Kim, Maengjo, Zhou, Bo, Cao, Yang, Ritterhoff, Julia, Gu, Haiwei, Raftery, Daniel, Sun, Haipeng, Tian, Rong

“…Elevated levels of branched-chain amino acids (BCAAs) have recently been implicated in the development of cardiovascular and metabolic diseases, but the…”
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Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma by Panou, Vasiliki, Gadiraju, Meghana, Wolin, Arthur, Weipert, Caroline M, Skarda, Emily, Husain, Aliya N, Patel, Jyoti D, Rose, Buerkley, Zhang, Shannon R, Weatherly, Madison, Nelakuditi, Viswateja, Knight Johnson, Amy, Helgeson, Maria, Fischer, David, Desai, Arpita, Sulai, Nanna, Ritterhouse, Lauren, Røe, Oluf D, Turaga, Kiran K, Huo, Dezheng, Segal, Jeremy, Kadri, Sabah, Li, Zejuan, Kindler, Hedy L, Churpek, Jane E

“…The aim of the current study was to determine the prevalence and clinical predictors of germline cancer susceptibility mutations in patients with malignant…”
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Headspace, a youth integrated care model: The relation between users satisfaction, clinical and demographic characteristics and service utilization by Hoter Ishay, G., Roe, D.

“…Introduction Youth integrated care services were developed to overcome common barriers to mental health treatment. Satisfaction is key for services utilization…”
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Increasing Fatty Acid Oxidation Prevents High-Fat Diet–Induced Cardiomyopathy Through Regulating Parkin-Mediated Mitophagy by Shao, Dan, Kolwicz, Stephen C., Wang, Pei, Roe, Nathan D., Villet, Outi, Nishi, Kiyoto, Hsu, Yun-Wei A., Flint, Galina V., Caudal, Arianne, Wang, Wang, Regnier, Michael, Tian, Rong

“…Increased fatty acid oxidation (FAO) has long been considered a culprit in the development of obesity/diabetes mellitus-induced cardiomyopathy. However,…”
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The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease by Hopp, Sarah C, Lin, Yang, Oakley, Derek, Roe, Allyson D, DeVos, Sarah L, Hanlon, David, Hyman, Bradley T

“…Misfolding of microtubule-associated protein tau (MAPT) within neurons into neurofibrillary tangles is an important pathological feature of Alzheimer's disease…”
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Genomic biosurveillance of forest invasive alien enemies: A story written in code by Hamelin, Richard C., Roe, Amanda D.

“…The world's forests face unprecedented threats from invasive insects and pathogens that can cause large irreversible damage to the ecosystems. This threatens…”
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Normalization of NAD+ Redox Balance as a Therapy for Heart Failure by Lee, Chi Fung, Chavez, Juan D, Garcia-Menendez, Lorena, Choi, Yongseon, Roe, Nathan D, Chiao, Ying Ann, Edgar, John S, Goo, Young Ah, Goodlett, David R, Bruce, James E, Tian, Rong

“…BACKGROUND:Impairments of mitochondrial function in the heart are linked intricately to the development of heart failure, but there is no therapy for…”
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Posttraumatic growth in psychosis: Symptoms, meaning, and coping by Mazor, Y., Gelkopf, M., Roe, D.

“…Introduction Research suggested that psychosis and mental illness-related experiences can be extremely traumatic, and that psychosis could theoretically also…”
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Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain by Takeda, Shuko, Wegmann, Susanne, Cho, Hansang, DeVos, Sarah L., Commins, Caitlin, Roe, Allyson D., Nicholls, Samantha B., Carlson, George A., Pitstick, Rose, Nobuhara, Chloe K., Costantino, Isabel, Frosch, Matthew P., Müller, Daniel J., Irimia, Daniel, Hyman, Bradley T.

“…Tau pathology is known to spread in a hierarchical pattern in Alzheimer’s disease (AD) brain during disease progression, likely by trans-synaptic tau transfer…”
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Promoting better mental health care for patients with psychosis by focusing on differences in causal beliefs between patients and clinicians by Rosenthal Oren, R., Roe, D., Hasson-Ohayon, I., Zisman-Ilani, Y.

“…Introduction Nonadherence to antipsychotic medications and disengagement from psychiatric services are frequent among people with psychosis. Research indicates…”
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Feature engineering with clinical expert knowledge: A case study assessment of machine learning model complexity and performance by Roe, Kenneth D, Jawa, Vibhu, Zhang, Xiaohan, Chute, Christopher G, Epstein, Jeremy A, Matelsky, Jordan, Shpitser, Ilya, Taylor, Casey Overby

“…Incorporating expert knowledge at the time machine learning models are trained holds promise for producing models that are easier to interpret. The main…”
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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro by Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko

“…The clinical progression of Alzheimer disease (AD) is associated with the accumulation of tau neurofibrillary tangles, which may spread throughout the cortex…”
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Advances in research on the impacts of anti-submarine sonar on beaked whales by Bernaldo de Quirós, Y, Fernandez, A, Baird, R W, Brownell, Jr, R L, Aguilar de Soto, N, Allen, D, Arbelo, M, Arregui, M, Costidis, A, Fahlman, A, Frantzis, A, Gulland, F M D, Iñíguez, M, Johnson, M, Komnenou, A, Koopman, H, Pabst, D A, Roe, W D, Sierra, E, Tejedor, M, Schorr, G

“…Mass stranding events (MSEs) of beaked whales (BWs) were extremely rare prior to the 1960s but increased markedly after the development of naval mid-frequency…”
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Cross-sectional associations between adipose tissue depots and areal bone mineral density in the UK Biobank imaging study by Bland, V. L., Klimentidis, Y. C., Bea, J. W., Roe, D. J., Funk, J. L., Going, S. B.

“…Summary The relationship between obesity and osteoporosis is poorly understood. In this study, we assessed the association between adiposity and bone. The…”
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Characterization of TauC3 antibody and demonstration of its potential to block tau propagation by Nicholls, Samantha B, DeVos, Sarah L, Commins, Caitlin, Nobuhara, Chloe, Bennett, Rachel E, Corjuc, Diana L, Maury, Eduardo, Eftekharzadeh, Bahareh, Akingbade, Ololade, Fan, Zhanyun, Roe, Allyson D, Takeda, Shuko, Wegmann, Susanne, Hyman, Bradley T

“…The spread of neurofibrillary tangle (NFT) pathology through the human brain is a hallmark of Alzheimer's disease (AD), which is thought to be caused by the…”
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Baseline Serum Prostate-specific Antigen Value Predicts the Risk of Subsequent Prostate Cancer Death—Results from the Norwegian Prostate Cancer Consortium by Bjerner, Johan, Bratt, Ola, Aas, Kirsti, Albertsen, Peter C., Fosså, Sophie D., Kvåle, Rune, Lilja, Hans, Müller, Christoph, Müller, Stig, Stensvold, Andreas, Thomas, Owen, Røe, Oluf D., Vickers, Andrew, Walz, Jochen, Carlsson, Sigrid V., Oldenburg, Jan

“…Among 40- to 70-yr-old men with a “normal” prostate-specific antigen (PSA) value (below 4 ng/ml) sampled in routine medical care, the risk of dying from…”
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A glimmer of hope – ash genotypes with increased resistance to ash dieback pathogen show cross‐resistance to emerald ash borer by Gossner, Martin M., Perret‐Gentil, Anouchka, Britt, Elisabeth, Queloz, Valentin, Glauser, Gaétan, Ladd, Tim, Roe, Amanda D., Cleary, Michelle, Liziniewicz, Mateusz, Nielsen, Lene R., Ghosh, Soumya K., Bonello, Pierluigi, Eisenring, Michael

“…Summary Plants rely on cross‐resistance traits to defend against multiple, phylogenetically distinct enemies. These traits are often the result of long…”
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The Sleep Side of Aging and Alzheimer’s Disease by Romanella, S.M., Roe, D., Tatti, E., Cappon, D., Paciorek, R., Testani, E., Rossi, A., Rossi, S., Santarnecchi, E.

“…As we age, sleep patterns undergo significant modifications in micro and macrostructure, worsening cognition and quality of life. These are associated with…”
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Pathology and molecular epidemiology of Mycobacterium pinnipedii tuberculosis in native New Zealand marine mammals by Roe, Wendi D, Lenting, Baukje, Kokosinska, Anna, Hunter, Stuart, Duignan, Padraig J, Gartrell, Brett, Rogers, Lynn, Collins, Desmond M, de Lisle, Geoffrey W, Gedye, Kristene, Price-Carter, Marian

“…Mycobacterium pinnipedii causes tuberculosis in a number of pinniped species, and transmission to cattle and humans has been reported. The aims of this study…”
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Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients by Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E., Trisini Lipsanopoulos, Ana T., Scherzer, Clemens R., Carlson, George A., Pitstick, Rose, Peskind, Elaine R., Raskind, Murray A., Li, Ge, Montine, Thomas J., Frosch, Matthew P., Hyman, Bradley T.

“…Objective Cerebrospinal fluid (CSF) tau is an excellent surrogate marker for assessing neuropathological changes that occur in Alzheimer's disease (AD)…”
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