Search Results - "Rodriguez Burbano, Rommel"
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The cosmetic dye quinoline yellow causes DNA damage in vitro
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-01-2015)“…•Quinoline yellow (QY) proved to be genotoxic on HepG2 cells using the comet assay.•Low QY concentrations were genotoxic by cytokinesis-block micronucleus…”
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Cytotoxic and Genotoxic Effects of Fluconazole on African Green Monkey Kidney (Vero) Cell Line
Published in BioMed research international (01-01-2018)“…Fluconazole is a broad-spectrum triazole antifungal that is well-established as the first-line treatment for Candida albicans infections. Despite its extensive…”
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3
Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer
Published in World journal of gastroenterology : WJG (21-09-2016)“…Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large…”
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MicroRNAs as a Potential Quality Measurement Tool of Platelet Concentrate Stored in Blood Banks-A Review
Published in Cells (Basel, Switzerland) (15-10-2019)“…Platelet concentrate (PC) is one of the main products used in a therapeutic transfusion. This blood component requires special storage at blood banks, however,…”
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Analysis of Increased EGFR and IGF-1R Signaling and Its Correlation with Socio-Epidemiological Features and Biological Profile in Breast Cancer Patients: A Study in Northern Brazil
Published in Breast cancer targets and therapy (01-01-2021)“…Breast cancer (BC) is the second most frequent cancer worldwide. It is known that a subset of BC has amplification, and overexpression of the epidermal growth…”
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1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line
Published in International journal of molecular sciences (23-07-2022)“…The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of chronic myeloid leukemia (CML) in advantage stages such as blast…”
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The anthelmintic drug mebendazole inhibits growth, migration and invasion in gastric cancer cell model
Published in Toxicology in vitro (01-12-2015)“…The present study aimed to investigate the effects of MBZ on a human malignant ascites cell line derived from a primary gastric cancer tumor. Our data reveal…”
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Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow
Published in Anticancer research (01-03-2015)“…Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group. Studies about its genotoxic, cytotoxic and mutagenic…”
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In Vitro Cytotoxic Effects and Mechanisms of Action of Eleutherine Isolated from Eleutherine plicata Bulb in Rat Glioma C6 Cells
Published in Molecules (Basel, Switzerland) (13-12-2022)“…Gliomas are the most common primary malignant brain tumors in adults, and have a poor prognosis, despite the different types of treatment available. There is…”
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Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches
Published in Arabian journal of chemistry (01-04-2021)“…The biological activities of Eleutherine plicata Herb. have been linked to isoeleutherin and eleutherin naphthoquinones. However, there are few reports in the…”
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Efficacy and safety of PD-1/PD-L1 inhibitors in patients with Merkel Cell Carcinoma: a systematic review and Meta-analysis
Published in BMC cancer (06-11-2024)“…Background Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer characterized by high rates of metastasis. Emerging evidence…”
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Research for Cytomegalovirus Mutations Associated With Resistance to Antivirals in Kidney Transplant Receptors
Published in Cell transplantation (01-01-2023)“…Cytomegalovirus (CMV) mutations associated with antiviral resistance have become a major problem related to high mortality in kidney transplant patients. The…”
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MicroRNA 320a and Membrane Antigens as Tools to Evaluate the Pathophysiology of Platelets Stored in Blood Banks
Published in Current issues in molecular biology (22-04-2022)“…Our research group, through the analysis of miRNomes in platelet concentrates (PCs) stored in blood banks, identified and validated the miR-127 and miR-320a…”
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The miRNA Profile of Platelets Stored in a Blood Bank and Its Relation to Cellular Damage from Storage
Published in PloS one (29-06-2015)“…Millions of blood products are transfused each year, and many lives are directly affected by transfusion. Platelet concentrate (PC) is one of the main products…”
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Prevention of congenital chagas disease by trypanocide treatment in women of reproductive age: A meta-analysis of observational studies
Published in PLoS neglected tropical diseases (05-09-2024)“…Maternal-foetal transmission of Chagas disease (CD) affects newborns worldwide. Although Benznidazole and Nifurtimox therapies are the standard treatments,…”
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Efficacy and safety of Zolbetuximab plus chemotherapy for advanced CLDN18.2-positive gastric or gastro-oesophageal adenocarcinoma: a meta-analysis of randomized clinical trials
Published in BMC cancer (21-02-2024)“…The benefit of adding Zolbetuximab to the treatment in patients with Claudin-18 isoform 2 (CLDN18.2)-positive, human epidermal growth factor receptor…”
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The protective effect of Canova homeopathic medicine in cyclophosphamide-treated non-human primates
Published in Food and chemical toxicology (01-12-2012)“…► We evaluated Canova effects on non-human primate treated with cyclophosphamide. ► Cyclophosphamide induced abnormal WBC count, micronucleus and DNA damage in…”
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The potential European genetic predisposition for non-contact anterior cruciate ligament injury
Published in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (01-12-2018)“…Purpose Previous research has provided evidence of a hereditary predisposition for anterior cruciate ligament (ACL) injury. The purpose of this study was to…”
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PD-L1 Expression Associated with Epstein-Barr Virus Status and Patients' Survival in a Large Cohort of Gastric Cancer Patients in Northern Brazil
Published in Cancers (22-06-2021)“…Gastric cancer (GC) is a worldwide health problem, making it one of the most common types of cancer, in fifth place of all tumor types, and the third highest…”
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C-MYC Locus Amplification as Metastasis Predictor in Intestinal-type Gastric Adenocarcinomas: CGH Study in Brazil
Published in Anticancer research (01-07-2006)“…Background: The genetic events involved in gastric cancer, the third most frequent cancer in the world with a high incidence in Pará State, Brazil, remain…”
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