Search Results - "Rodriguez‐Lescure, Alvaro"
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Epirubicin Plus Cyclophosphamide Followed by Docetaxel Versus Epirubicin Plus Docetaxel Followed by Capecitabine As Adjuvant Therapy for Node-Positive Early Breast Cancer: Results From the GEICAM/2003-10 Study
Published in Journal of clinical oncology (10-11-2015)“…Capecitabine is an active drug in metastatic breast cancer (BC). GEICAM/2003-10 is an adjuvant trial to investigate the integration of capecitabine into a…”
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PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer
Published in Breast cancer research and treatment (01-04-2013)“…To identify a group of patients who might benefit from the addition of weekly paclitaxel to conventional anthracycline-containing chemotherapy as adjuvant…”
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Fluorouracil, Doxorubicin, and Cyclophosphamide (FAC) Versus FAC Followed by Weekly Paclitaxel As Adjuvant Therapy for High-Risk, Node-Negative Breast Cancer: Results From the GEICAM/2003-02 Study
Published in Journal of clinical oncology (10-07-2013)“…Adding taxanes to anthracycline-based adjuvant therapy improves survival outcomes of patients with node-positive breast cancer (BC). Currently, however, most…”
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A Pathology-Based Combined Model to Identify PAM50 Non-luminal Intrinsic Disease in Hormone Receptor-Positive HER2-Negative Breast Cancer
Published in Frontiers in oncology (26-04-2019)“…In hormone receptor-positive (HR+)/HER2-negative breast cancer, the HER2-enriched and Basal-like intrinsic subtypes are associated with poor outcome, low…”
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Nab-Paclitaxel in Metastatic Breast Cancer: Defining the Best Patient Profile
Published in Current cancer drug targets (01-06-2016)“…Around 40% of patients with breast cancer will present with a recurrence of the disease. Chemotherapy is recommended for patients with recurrent…”
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Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression
Published in The oncologist (Dayton, Ohio) (01-05-2015)“…Purpose. To determine intrinsic breast cancer subtypes represented within categories defined by quantitative hormone receptor (HR) and HER2 expression…”
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Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial
Published in The lancet oncology (2013)“…Summary Background We compared standard adjuvant anthracycline chemotherapy with anthracycline–taxane combination chemotherapy in women with operable…”
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PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers
Published in BMC medical genomics (04-10-2012)“…Many methodologies have been used in research to identify the "intrinsic" subtypes of breast cancer commonly known as Luminal A, Luminal B, HER2-Enriched…”
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Adjuvant Docetaxel for High-Risk, Node-Negative Breast Cancer
Published in The New England journal of medicine (02-12-2010)“…As compared with the standard regimen, the combination of docetaxel, doxorubicin, and cyclophosphamide reduced the risk of recurrence of node-negative…”
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Lack of cytomegalovirus detection in human glioma
Published in Virology journal (07-11-2017)“…Gliomas are the most common brain tumors and include a variety of histologic types and grades of malignancy. They arise from glial cells and represent…”
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Assessment of a Genomic Assay in Patients With ERBB2-Positive Breast Cancer Following Neoadjuvant Trastuzumab-Based Chemotherapy With or Without Pertuzumab
Published in JAMA oncology (01-06-2023)“…Biomarkers to guide the use of pertuzumab in the treatment of early-stage ERBB2 (formerly HER2)-positive breast cancer beyond simple ERBB2 status are needed…”
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Impact of the COVID-19 pandemic on the diagnosis and treatment of onco-hematologic patients: a discussion paper
Published in Revista española de quimioterapia (01-02-2023)“…We do not know the precise figure for solid organ tumors diagnosed each year in Spain and it is therefore difficult to calculate whether there has been a…”
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Adjuvant chemotherapy in young women with breast cancer
Published in Breast cancer research and treatment (01-09-2010)“…The issue of whether young women with breast cancer should be treated differently from older women is a matter of debate, partly because of the lack of…”
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PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines
Published in Cells (Basel, Switzerland) (06-09-2018)“…Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms…”
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Prediction of chemotherapy benefit by EndoPredict in patients with breast cancer who received adjuvant endocrine therapy plus chemotherapy or endocrine therapy alone
Published in Breast cancer research and treatment (01-07-2019)“…Purpose EndoPredict (EPclin) is a prognostic test validated to inform decisions on adjuvant chemotherapy to endocrine therapy alone for patients with oestrogen…”
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SEOM clinical guidelines for the treatment of early breast cancer
Published in Clinical & translational oncology (01-11-2010)“…The incidence is increasing due to mammographic screening and an ageing population. In some countries the mortality rate has decreased especially in middleaged…”
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SEOM clinical guidelines for the treatment of metastatic breast cancer
Published in Clinical & translational oncology (01-11-2010)“…Patients with metastatic breast cancer have a wide number of treatment options, including medical, surgical, and supportive care measures. Treatment decisions…”
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CLytA-DAAO Chimeric Enzyme Bound to Magnetic Nanoparticles. A New Therapeutical Approach for Cancer Patients?
Published in International journal of molecular sciences (02-02-2021)“…D-amino acid oxidase (DAAO) is an enzyme that catalyzes the oxidation of D-amino acids generating H O . The enzymatic chimera formed by DAAO bound to the…”
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Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled analysis
Published in Breast cancer research : BCR (06-11-2013)“…Obesity is an unfavorable prognostic factor in breast cancer (BC) patients regardless of menopausal status and treatment received. However, the association…”
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Advanced breast cancer: chemotherapy phase III trials that change a standard
Published in Anti-cancer drugs (01-08-2007)“…At the present time, there is not a standard regimen in upfront metastatic setting for breast cancer. A wide variety of regimens which includes anthracyclines,…”
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