Search Results - "Rodriguez, Princess D"

Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia by Rodriguez, Princess D, Paculova, Hana, Kogut, Sophie, Heath, Jessica, Schjerven, Hilde, Frietze, Seth

“…Non-coding RNAs (ncRNAs) comprise a diverse class of non-protein coding transcripts that regulate critical cellular processes associated with cancer. Advances…”
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Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists by Curtis, Kylie D, Smith, Portia R, Despres, Hannah W, Snyder, Julia P, Hogan, Tyler C, Rodriguez, Princess D, Amiel, Eyal

“…Dendritic cells (DCs) increase their metabolic dependence on glucose and glycolysis to support their maturation, activation-associated cytokine production, and…”
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Thyroid Hormone Receptor Beta Induces a Tumor-Suppressive Program in Anaplastic Thyroid Cancer by Bolf, Eric L, Gillis, Noelle E, Davidson, Cole D, Rodriguez, Princess D, Cozzens, Lauren, Tomczak, Jennifer A, Frietze, Seth, Carr, Frances E

“…The thyroid hormone receptor beta (TRβ), a key regulator of cellular growth and differentiation, is frequently dysregulated in cancers. Diminished expression…”
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A kindred with mutant IKAROS and autoimmunity by Van Nieuwenhove, Erika, Garcia-Perez, Josselyn E., Helsen, Christine, Rodriguez, Princess D., van Schouwenburg, Pauline A., Dooley, James, Schlenner, Susan, van der Burg, Mirjam, Verhoeyen, Els, Gijsbers, Rik, Frietze, Seth, Schjerven, Hilde, Meyts, Isabelle, Claessens, Frank, Humblet-Baron, Stephanie, Wouters, Carine, Liston, Adrian

“…IKAROS (encoded by IKZF1) is an important hematopoietic transcription factor critical for early B cell differentiation, with major defects known to lead to low…”
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Syk‐dependent glycolytic reprogramming in dendritic cells regulates IL‐1β production to β‐glucan ligands in a TLR‐independent manner by Thwe, Phyu M., Fritz, Daniel I., Snyder, Julia P., Smith, Portia R., Curtis, Kylie D., O'Donnell, Alexandra, Galasso, Nicholas A., Sepaniac, Leslie A., Adamik, Benjamin J., Hoyt, Laura R., Rodriguez, Princess D., Hogan, Tyler C., Schmidt, Andrea F., Poynter, Matthew E., Amiel, Eyal

“…Dendritic cells (DCs) activated via TLR ligation experience metabolic reprogramming, in which the cells are heavily dependent on glucose and glycolysis for the…”
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A guided‐inquiry investigation of genetic variants using Oxford nanopore sequencing for an undergraduate molecular biology laboratory course by Rodriguez, Princess D., Mariani, Michael, Gay, Jamie, Hogan, Tyler C., Amiel, Eyal, Deming, Paula B., Frietze, Seth

“…Next Generation Sequencing (NGS) has become an important tool in the biological sciences and has a growing number of applications across medical fields…”
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Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Fidelity of Mechanisms Governing the Cell Cycle by El Dika, Mohammed, Fritz, Andrew J, Toor, Rabail H, Rodriguez, Princess D, Foley, Stephen J, Ullah, Rahim, Nie, Daijing, Banerjee, Bodhisattwa, Lohese, Dorcas, Tracy, Kirsten M, Glass, Karen C, Frietze, Seth, Ghule, Prachi N, Heath, Jessica L, Imbalzano, Anthony N, van Wijnen, Andre, Gordon, Jonathan, Lian, Jane B, Stein, Janet L, Stein, Gary S

“…The cell cycle is governed by stringent epigenetic mechanisms that, in response to intrinsic and extrinsic regulatory cues, support fidelity of DNA replication…”
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Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype by Fritz, Andrew J, El Dika, Mohammed, Toor, Rabail H, Rodriguez, Princess D, Foley, Stephen J, Ullah, Rahim, Nie, Daijing, Banerjee, Bodhisattwa, Lohese, Dorcas, Tracy, Kirsten M, Glass, Karen C, Frietze, Seth, Ghule, Prachi N, Heath, Jessica L, Imbalzano, Anthony N, van Wijnen, Andre, Gordon, Jonathan, Lian, Jane B, Stein, Janet L, Stein, Gary S

“…Epigenetic gene regulatory mechanisms play a central role in the biological control of cell and tissue structure, function, and phenotype. Identification of…”
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Ikaros establishes an epigenetic program required for proper two-signal activation of naive B cells by Rodriguez, Princess D., Schjerven, Hilde, Amiel, Eyal, Frietze, Seth

“…While there are many different types of autoimmune diseases, a common feature of chronic inflammatory diseases is the production of autoantibodies by B-cells…”
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Ikaros regulates gene expression programs required for proper BCR-activation in mature B cells by Rodriguez, Princess D, Howell, William, Boyd, Joseph, Frietze, Seth, Schjerven, Hilde

“…The zinc-finger (ZnF) transcription factor Ikaros (encoded by Ikzf1) plays an essential role in regulating transcriptional programs required for B cell…”
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Ikaros mutations can bypass the requirement for second co-stimulatory signal and lead to break of B-cell tolerance by Schjerven, Hilde, Rodriguez, Princess D, Howell, William, Vestbostad, Johanne, Frietze, Seth, Schjerven, Hilde

“…Autoimmunity is thought to arise due to a combination of genetic and environmental factors. IKZF1, encoding the Zinc finger (ZnF) transcription factor Ikaros,…”
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Ikaros regulates chromatin landscape in mature B cells, and is critical for B cell tolerance by Rodriguez, Princess D, Howell, William, Amiel, Eyal, Frietze, Seth, Schjerven, Hilde

“…The zinc finger transcription factor Ikaros plays central roles in the gene regulatory programs associated with proper B cell development. While mutations in…”
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A kindred with mutant IKAROS and autoimmunity by Van Nieuwenhove, Erika, Garcia-Perez, Josselyn E, Helsen, Christine, Rodriguez, Princess D, van Schouwenburg, Pauline A, Dooley, James, Schlenner, Susan, van der Burg, Mirjam, Verhoeyen, Els, Gijsbers, Rik, Frietze, Seth, Schjerven, Hilde, Meyts, Isabelle, Claessens, Frank, Humblet-Baron, Stephanie, Wouters, Carine, Liston, Adrian

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