Search Results - "Rodriguez, Javier Saiz"

Optimisation of ultrasound liver perfusion through a digital reference object and analysis tool by Alberich-Bayarri, Ángel, Tomás-Cucarella, Jose, Torregrosa-Lloret, Alfredo, Sáiz Rodriguez, Javier, Martí-Bonmatí, Luis

“…Background Conventional ultrasound (US) provides important qualitative information, although there is a need to evaluate the influence of the input parameters…”
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Simulation of the effects of flecainide and ranolazine under LQTS type 3 produced by the heterozygous SCN5A V411M mutant by García, Jordi Cano, Arnau, Miguel, Zorio, Esther, Rodriguez, Javier Saiz, Pérez, Lucía Romero

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Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials by Zemzemi, Nejib, Bernabeu, Miguel O, Saiz, Javier, Cooper, Jonathan, Pathmanathan, Pras, Mirams, Gary R, Pitt‐Francis, Joe, Rodriguez, Blanca

“…Background and Purpose Understanding drug effects on the heart is key to safety pharmacology assessment and anti‐arrhythmic therapy development. Here our goal…”
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IC50 evaluation is critically dependent on the protocol used for measurement by Dolz, Julio Gomis-Tena, Brown, Brandon M., García, Jordi Cano, Trenor, Beatriz, Yang, Pei-Chi, Rodriguez, Javier Saiz, Clancy, Colleen E., Romero, Lucia

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Use of the comprehensive in vitro proarrhythmia assay and in silico modeling to investigate the safety profile of bisphenol analogues by Jaimes, Rafael, McCullough, Damon, Swift, Luther, Reilly, Marissa, Burke, Morgan, Lorente, Jordi Llopis, Gomis, Beatriz Trénor, Rodriguez, Javier Saiz, Sheng, Jiansong, Posnack, Nikki G.

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In silico classifier for early screening of drug-induced torsadogenic risk by Lorente, Jordi Llopis, García, Jordi Cano, Dolz, Julio Gomis-Tena, Pérez, Lucía Romero, Carreras, Ferran Sanz, Maeso, Manuel Pastor, Gomis, Beatriz Trénor, Rodriguez, Javier Saiz

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Distinction of IKr blockers based on channel state preference using voltage clamp simulations and machine learning by Ropero, Fernando Escobar, Dolz, Julio Gomis-Tena, Rodríguez, Francisco Javier Saiz, Pérez, Lucía Romero

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In silico study of drug effects on human non-failing and failing cardiomyocytes by Lorente, Jordi Llopis, Dolz, Julio Gomis-Tena, Pérez, Lucía Romero, Rodríguez, Francisco Javier Saiz, Gomis, Beatriz Trénor

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Role of L-type calcium in modulating pro-arrhythmic effects of dofetilide in humans by Zemzemi, N., Rodriguez, J. S., Rodriguez, B.

“…Dofetilide is a class III drug whose use needs to be monitored due to the possible occurrence of Torsades de Pointes (TdP). The mechanisms are unclear but…”
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