Intestinal Biomarkers and Their Importance in Canine Enteropathies

Intestinal Biomarkers and Their Importance in Canine Enteropathies

Enteropathies are prevalent in dog internal medicine, and their diagnosis involves a lengthy process. One of the tests requested is for biomarkers, which are important as they can provide data on intestinal functionality, intensity of inflammation, and response to treatment, and can help determine t...

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Bibliographic Details
Published in:Veterinary medicine international Vol. 2024; no. 1
Main Authors: Oliveira, Iago Martins, Ribeiro, Rafaela Rodrigues, Cardoso Cysneiros, Maria Eduarda, Torres, Larissa Barbosa, Moraes, Vanessa Rezende, Ferreira, Lucas Rodrigues, Rodrigues da Silva, Wanessa Patrícia, Rodrigues de Souza, Murilo, Lopes Xavier, Rafael Antônio, Renato dos Santos Costa, Paulo, Martins, Danieli Brolo, Borges, Naida Cristina
Format: Journal Article
Language:English
Published: New York John Wiley & Sons, Inc 01-01-2024
Hindawi Limited
Wiley
Subjects:
Biological markers
Biomarkers
C-reactive protein
Chromatography
Development and progression
Diagnosis
Disease
Dogs
Dysbacteriosis
Enzymes
Feces
Folic acid
Immunoglobulin A
Immunoglobulins
Inflammation
Intestine
Laboratories
Literature reviews
Prognosis
Proteins
Veterinary medicine
Vitamin B12
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Summary:Enteropathies are prevalent in dog internal medicine, and their diagnosis involves a lengthy process. One of the tests requested is for biomarkers, which are important as they can provide data on intestinal functionality, intensity of inflammation, and response to treatment, and can help determine the prognosis. This study aimed to conduct a literature review on the main serum and fecal intestinal biomarkers in dogs and proposed to refine the correlations between these indicators and enteropathies. It was observed that the main biomarkers used in the intestinal evaluation of dogs were alpha 1-proteinase inhibitory factor, immunoglobulin A, methylmalonic acid, serum folate, serum cobalamin, C-reactive protein, fecal and serum calprotectin, and dysbiosis index. However, we suggest that more research be carried out to clarify the relationship between enteropathies and intestinal biomarkers. We noticed a lack of studies on specific intestinal markers and indicator variables in healthy dogs and those with various enteropathies; moreover, no data are available on the association of these laboratory parameters.
ISSN:2090-8113
2042-0048
2042-0048
DOI:10.1155/vmi/7409482