Search Results - "Rodrigues de Oliveira, Natasha"
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Performance of Recombinant Nucleocapsid Protein-Based Constructs for Serological Diagnosis of SARS-CoV-2 Infection
Published in Brazilian Archives of Biology and Technology (01-01-2024)“…Abstract Since the inception of COVID-19 pandemic, there has been a challenging race for the development of precise diagnostic tests. Specific SARS-CoV-2…”
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Challenges and Strategies for Developing Recombinant Vaccines against Leptospirosis: Role of Expression Platforms and Adjuvants in Achieving Protective Efficacy
Published in Pathogens (Basel) (31-05-2023)“…The first leptospiral recombinant vaccine was developed in the late 1990s. Since then, progress in the fields of reverse vaccinology (RV) and structural…”
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Whole-genome sequencing of Leptospira interrogans from southern Brazil: genetic features of a highly virulent strain
Published in Memórias do Instituto Oswaldo Cruz (01-02-2018)“…BACKGROUND Leptospirosis is the most widespread zoonotic disease. It is caused by infection with pathogenic Leptospira species, of which over 300 serovars have…”
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4
Pathogenesis and genomic analysis of a virulent Leptospira interrogans serovar Copenhageni isolated from a dog with lethal infection
Published in Tropical medicine and infectious disease (28-10-2022)“…Dogs are highly susceptible to leptospirosis and are a public health concern due to their important role as a source of spreading disease, particularly in…”
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Occurrence of Mycoplasma hyopneumoniae in slaughter pigs from Southern Brazil
Published in Brazilian journal of veterinary research and animal science (28-06-2019)“…Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia (EP), a disease that is highly prevalent and globally distributed, causing significant…”
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Characterization of cellular immune response in hamsters immunized with recombinant vaccines against leptospirosis based on LipL32:LemA:LigAni chimeric protein
Published in Microbial pathogenesis (01-11-2023)“…In the last 20 years, various research groups have endeavored to develop recombinant vaccines against leptospirosis to overcome the limitations of commercially…”
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Protective efficacy of whole-cell inactivated Leptospira vaccines made using virulent or avirulent strains in a hamster model
Published in Vaccine (15-09-2021)“…Whole-cell inactivated vaccines remain the only licensed vaccines used to control human and animal leptospirosis worldwide. Although they are protective…”
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Three challenging cases of infections by multidrug-resistant Serratia marcescens in patients admitted to intensive care units
Published in Brazilian journal of microbiology (01-09-2021)“…The occurrence of multidrug-resistant Serratia marcescens strains represents a serious public health threat. The purpose here is to report three cases of…”
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Polymerase chain reaction and loop-mediated isothermal amplification targeting lic13162, lic20239, and lipL32 genes for leptospirosis diagnosis
Published in Brazilian journal of microbiology (01-06-2022)“…Leptospirosis is a zoonotic disease caused by pathogenic species of Leptospira . Due to the similarity with clinical signs of other febrile diseases, early…”
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Tp0684, Tp0750, and Tp0792 Recombinant Proteins as Antigens for the Serodiagnosis of Syphilis
Published in Indian journal of microbiology (01-09-2022)“…The incidence of syphilis has increased alarmingly over the years. Its diagnosis continues to be a challenge, leading to the search for new alternative and…”
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Campylobacter jejuni isolated from poultry meat in Brazil: in silico analysis and genomic features of two strains with different phenotypes of antimicrobial susceptibility
Published in Molecular biology reports (2020)“…Campylobacter jejuni is the most common bacterial cause of foodborne diarrheal disease worldwide and is among the antimicrobial resistant “priority pathogens”…”
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Seroepidemiological investigation of animal leptospirosis and molecular characterization of the first Leptospira strain isolated from Fernando de Noronha archipelago, Brazil
Published in Transboundary and emerging diseases (01-07-2021)“…Leptospirosis has been widely reported in insular environments worldwide, characterizing a major public health threat. Although low‐genetic biodiversity is…”
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Human and animal leptospirosis in Southern Brazil: A five-year retrospective study
Published in Travel medicine and infectious disease (01-07-2017)“…Leptospirosis is an emerging zoonosis attributed to multiple reservoirs. Climatic conditions influence the transmission of pathogenic leptospires, which…”
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Complete genome sequence of native Bacillus cereus strains isolated from intestinal tract of the crab Ucides sp
Published in Data in brief (01-02-2018)“…Bacillus cereus is a gram positive bacterium with sporulation capacity. Here, we report the complete genome sequence of two native B. cereus strains (#25 and…”
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Development of Human Recombinant Leptospirosis Vaccines
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Leptospirosis is a bacterial zoonotic disease with significant impact on health all over the world. Currently, bacterins are the only vaccines available for…”
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Chimeric lipoproteins for leptospirosis vaccine: immunogenicity and protective potential
Published in Applied microbiology and biotechnology (01-12-2024)“…Leptospirosis, a neglected zoonotic disease, is caused by pathogenic spirochetes belonging to the genus Leptospira and has one of the highest morbidity and…”
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Recombinant Live-Attenuated Salmonella Vaccine for Veterinary Use
Published in Vaccines (Basel) (26-11-2024)“…Vaccination is essential for maintaining animal health, with priority placed on safety and cost effectiveness in veterinary use. The development of recombinant…”
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Evaluation of protective efficacy, serological responses, and cytokine modulation induced by polyvalent Leptospira vaccines in hamsters
Published in Comparative immunology, microbiology and infectious diseases (01-05-2024)“…Whole-cell inactivated vaccines (bacterins) are the only licensed vaccines available for leptospirosis prevention and control, especially in domestic and farm…”
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Complete genome sequence and in silico analysis of L. interrogans Canicola strain DU114: A virulent Brazilian isolate phylogenetically related to serovar Linhai
Published in Genomics (San Diego, Calif.) (01-12-2019)“…Canine leptospirosis is often caused by Leptospira interrogans serovar Canicola. Infected dogs may become asymptomatic carriers of the pathogen, which leads to…”
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Whole-genome sequencing of Leptospira interrogans from southern Brazil: genetic features of a highly virulent strain
Published in Memórias do Instituto Oswaldo Cruz (20-11-2021)“…BACKGROUND Leptospirosis is the most widespread zoonotic disease. It is caused by infection with pathogenic Leptospira species, of which over 300 serovars have…”
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