Search Results - "Rodrigues de Carvalho, Nelson"
-
1
Exposure of Drosophila melanogaster to Mancozeb Induces Oxidative Damage and Modulates Nrf2 and HSP70/83
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Mancozeb (MZ), a manganese- and zinc-containing ethylene-bis-dithiocarbamate, is a broad-spectrum fungicide. Harmful effects of this fungicide have been…”
Get full text
Journal Article -
2
Mancozeb impairs mitochondrial and bioenergetic activity in Drosophila melanogaster
Published in Heliyon (01-01-2021)“…Mancozeb (MZ) is a broad-spectrum fungicide used worldwide in several crops. Neurological disorders in humans and animals have been associated with exposure to…”
Get full text
Journal Article -
3
Anacardium microcarpum Promotes Neuroprotection Dependently of AKT and ERK Phosphorylation but Does Not Prevent Mitochondrial Damage by 6-OHDA
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Parkinson’s disease is a degenerative and progressive illness characterized by the degeneration of dopaminergic neurons. 6-hydroxydopamine (6-OHDA) is a…”
Get full text
Journal Article -
4
Effect of diselenide administration in thioacetamide-induced acute neurological and hepatic failure in mice
Published in Toxicology research (Cambridge) (01-01-2015)“…Hepatic encephalopathy is a common complication of severe acute hepatic failure and has been associated with high short-term mortality rates. Therefore, the…”
Get full text
Journal Article -
5
Permissible concentration of mancozeb in Brazilian drinking water elicits oxidative stress and bioenergetic impairments in embryonic zebrafish
Published in Environmental pollution (1987) (15-09-2023)“…Mancozeb (MZ) is widely used as a fungicide in Brazil due to its effectiveness in combating fungal infections in plantations. However, its toxicity to…”
Get full text
Journal Article -
6
Protective action of ethanolic extract of Rosmarinus officinalis L. in gastric ulcer prevention induced by ethanol in rats
Published in Food and chemical toxicology (01-05-2013)“…[Display omitted] ► eeRo has antioxidant, vasodilator, anti-inflammatory activity as anti-ulcerogenic mechanisms. ► Ethanol induced macroscopic, microscopic…”
Get full text
Journal Article -
7
N-acetylcysteine inhibits Mancozeb-induced impairments to the normal development of zebrafish embryos
Published in Neurotoxicology and teratology (01-07-2018)“…Mancozeb (MZ), a manganese/zinc-containing ethylene-bis-dithiocarbamate (EBCD) fungicide has been claimed to present low acute toxicity and short environmental…”
Get full text
Journal Article -
8
The insertion of functional groups in organic selenium compounds promote changes in mitochondrial parameters and raise the antibacterial activity
Published in Bioorganic chemistry (01-05-2020)“…[Display omitted] •o-methoxy and p-methyl insertion altered the mitochondrial respiratory function.•Mitochondrial ROS production was reduced by organic…”
Get full text
Journal Article -
9
Mancozeb exposure results in manganese accumulation and Nrf2-related antioxidant responses in the brain of common carp Cyprinus carpio
Published in Environmental science and pollution research international (01-06-2018)“…Manganese (Mn)-containing dithiocarbamates such as Mancozeb (MZ) have been shown to induce oxidative stress-related toxicity in rodents and humans. However,…”
Get full text
Journal Article -
10
Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats
Published in Biomedicine & pharmacotherapy (01-03-2019)“…•Guanosine prevent mitochondrial dysfunction induced by calcium (Ca2+) misbalance.•Maintaining mitochondrial functionality and calcium homeostasis as one of…”
Get full text
Journal Article -
11
An active lifestyle induces positive antioxidant enzyme modulation in peripheral blood mononuclear cells of overweight/obese postmenopausal women
Published in Life sciences (1973) (15-01-2015)“…The aim of this study was to investigate the effects of an active lifestyle on mitochondrial functioning, viability, bioenergetics, and redox status markers in…”
Get full text
Journal Article -
12
Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish
Published in Oxidative medicine and cellular longevity (2019)“…Permethrin (PM) is a synthetic pyrethroid insecticide widely used as domestic repellent. Damage effects to nontarget organisms have been reported, particularly…”
Get full text
Journal Article -
13
Neuroprotective Effect of Diphenyl Diselenide in a Experimental Stroke Model: Maintenance of Redox System in Mitochondria of Brain Regions
Published in Neurotoxicity research (01-11-2014)“…Acute stroke is a major risk for morbidity and mortality in aging population. Mitochondrion has been the focus of a wide stroke-related research. This study…”
Get full text
Journal Article -
14
Acute Brain Damage Induced by Acetaminophen in Mice: Effect of Diphenyl Diselenide on Oxidative Stress and Mitochondrial Dysfunction
Published in Neurotoxicity research (01-04-2012)“…Organoselenium compounds exhibit antioxidant activity, as well as a variety of biological activities, with potential pharmacological and therapeutic…”
Get full text
Journal Article -
15
Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila
Published in Free radical biology & medicine (20-05-2018)“…Many studies have shown the effects of sleep deprivation in several aspects of health and disease. However, little is known about how mitochondrial…”
Get full text
Journal Article -
16
Effects of Rosmarinus officinalis L. (Laminaceae) essential oil on adult and larvae of Drosophila melanogaster
Published in Toxicology research (Cambridge) (01-10-2023)“…Abstract Rosmarinus officinalis (Lamiaceae family), also known as “alecrim,” is a perennial herb, typical of the Mediterranean region and widely distributed in…”
Get full text
Journal Article -
17
Senecio brasiliensis impairs eclosion rate and induces apoptotic cell death in larvae of Drosophila melanogaster
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-08-2017)“…Senecio brasilienis (Spreng) Less., is a species native from Brazil, popularly known as “Maria mole”, and known to induce hepatotoxicity due to its high…”
Get full text
Journal Article -
18
Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injury
Published in Brain research bulletin (01-10-2020)“…•Guanosine (GUO) showed neuroprotective effect after mild traumatic brain injury.•GUO treatment restored motor behaviour, cognition and memory.•GUO increased…”
Get full text
Journal Article -
19
Free radical scavenging in vitro and biological activity of diphenyl diselenide-loaded nanocapsules: DPDS-NCS antioxidant and toxicological effects
Published in International journal of nanomedicine (01-01-2015)“…Selenium compounds, such as diphenyl diselenide (DPDS), have been shown to exhibit biological activity, including antioxidant effects. However, the use of DPDS…”
Get full text
Journal Article -
20
Multiple mechanistic action of Rosmarinus officinalis L. extract against ethanol effects in an acute model of intestinal damage
Published in Biomedicine & pharmacotherapy (01-02-2018)“…[Display omitted] The high levels of oxidative stress and inflammation can be present in the etiology of degenerative intestinal pathologies associated with…”
Get full text
Journal Article