Search Results - "Rodrigues de Assis, Diego Rodney"
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SOCS2 modulates adipose tissue inflammation and expansion in mice
Published in The Journal of nutritional biochemistry (01-02-2020)“…Obesity is usually triggered by a nutrient overload that favors adipocyte hypertrophy and increases the number of pro-inflammatory cells and mediators into…”
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Tityus serrulatus scorpion venom as a potential drug source for Chagas' disease: Trypanocidal and immunomodulatory activity
Published in Clinical immunology (Orlando, Fla.) (01-05-2021)“…Current chemical therapies for Chagas Disease (CD) lack ability to clear Trypanosoma cruzi (Tc) parasites and cause severe side effects, making search for new…”
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4-Chlorophenylthioacetone-derived thiosemicarbazones as potent antitrypanosomal drug candidates: Investigations on the mode of action
Published in Bioorganic chemistry (01-08-2021)“…[Display omitted] •Thiophenol-2-ylidene-thiosemicarbazones tested against Trypanosoma cruzi (Tc).•The compounds possess potent trypanocidal capacity in vitro…”
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Erratum to “Potent anti-Toxoplasma gondii activity of 4-chlorophenylthioacetone-derived thiosemicarbazones: Involvement of CCR2 and CCR5 receptors and 5-lipoxygenase in the mode of action” [Med. Drug Discovery 18 (2023) 100157]
Published in Medicine in drug discovery (01-06-2024)Get full text
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Tityus serrulatus (Scorpion): From the Crude Venom to the Construction of Synthetic Peptides and Their Possible Therapeutic Application Against Toxoplasma gondii Infection
Published in Frontiers in cellular and infection microbiology (20-07-2021)“…Toxoplasmosis, caused by , is a major public concern owing to its neurotropic nature and high morbidity and mortality rates in immunocompromised patients and…”
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Potent anti-Toxoplasma gondii activity of 4-chlorophenylthioacetone-derived thiosemicarbazones: Involvement of CCR2 and CCR5 receptors and 5-lipoxygenase in the mode of action
Published in Medicine in drug discovery (01-06-2023)“…[Display omitted] •Thiosemicarbazones Ca and Cb represent potent anti-Toxoplasma drug candidates.•Ca and Cb attenuate Toxoplasma gondii (Tg) growth in…”
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