Search Results - "Rodrigues Pinto Ferreira, Ludmila"
-
1
MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes
Published in PLoS neglected tropical diseases (18-06-2015)“…Chagas disease is caused by the parasite Trypanosoma cruzi, and it begins with a short acute phase characterized by high parasitemia followed by a life-long…”
Get full text
Journal Article -
2
Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?
Published in Critical care (London, England) (15-03-2018)“…Exosomes isolated from plasma of patients with sepsis may induce vascular apoptosis and myocardial dysfunction by mechanisms related to inflammation and…”
Get full text
Journal Article -
3
Integrative analysis of microRNA and mRNA expression profiles of monocyte‐derived dendritic cells differentiation during experimental cerebral malaria
Published in Journal of leukocyte biology (01-10-2020)“…Heterogeneity and high plasticity are common features of cells from the mononuclear phagocyte system: monocytes (MOs), macrophages, and dendritic cells (DCs)…”
Get full text
Journal Article -
4
Myocardial Infarction–Associated Transcript, a Long Noncoding RNA, Is Overexpressed During Dilated Cardiomyopathy Due to Chronic Chagas Disease
Published in The Journal of infectious diseases (01-07-2016)“…Long noncoding RNAs (lncRNAs) modulate gene expression at the epigenetic, transcriptional, and posttranscriptional levels. Dysregulation of the lncRNA known as…”
Get full text
Journal Article -
5
Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection
Published in Scientific reports (21-12-2017)“…Chagas disease, caused by the parasite Trypanosoma cruzi , is endemic in Latin America. Its acute phase is associated with high parasitism, myocarditis and…”
Get full text
Journal Article -
6
MiRNA-30d and miR-770-5p as potential clinical risk predictors of Vasoplegic Syndrome in Patients undergoing on-pump coronary artery bypass grafting
Published in Scientific reports (06-02-2023)“…The aims of this study were to perform pre-surgery miRNA profiling of patients who develop Vasoplegic syndrome (VS) after coronary artery bypass grafting…”
Get full text
Journal Article -
7
Rare Pathogenic Variants in Mitochondrial and Inflammation-Associated Genes May Lead to Inflammatory Cardiomyopathy in Chagas Disease
Published in Journal of clinical immunology (01-07-2021)“…Cardiomyopathies are an important cause of heart failure and sudden cardiac death. Little is known about the role of rare genetic variants in inflammatory…”
Get full text
Journal Article -
8
Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs
Published in Frontiers in cellular and infection microbiology (17-03-2022)“…Chronic Chagas disease (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis compared to other cardiomyopathies. We show the expression and…”
Get full text
Journal Article -
9
Soluble PD‐1 and PD‐L1 as potential biomarkers for classical Hodgkin lymphoma
Published in Hematological oncology (01-10-2018)Get full text
Journal Article -
10
Plasma cytokine profile in tropical endomyocardial fibrosis: predominance of TNF-a, IL-4 and IL-10
Published in PloS one (10-10-2014)“…The participation of immune/inflammatory mechanisms in the pathogenesis of tropical endomyocardial fibrosis (EMF) has been suggested by the finding of early…”
Get full text
Journal Article -
11
Induction of IL-12 Production in Human Peripheral Monocytes by Trypanosoma cruzi Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-γ and CD40-CD40L Interactions
Published in Mediators of inflammation (01-01-2014)“…Chagas disease, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), is characterized by immunopathology driven by IFN-γ secreting Th1-like T cells…”
Get full text
Journal Article -
12
Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy
Published in World journal of cardiology (26-08-2014)“…Chagas disease cardiomyopathy(CCC), the main consequence of Trypanosoma cruzi(T.cruzi) infection, is an inflammatory cardiomyopathy that develops in up to 30%…”
Get full text
Journal Article -
13
MicroRNAs miR - 1 , miR - 133a , miR - 133b , miR - 208a and miR - 208b are dysregulated in Chronic Chagas disease Cardiomyopathy
Published in International journal of cardiology (20-08-2014)“…Abstract Background/methods Chagas disease is caused by an intracellular parasite, Trypanosoma cruzi , and it is a leading cause of heart failure in Latin…”
Get full text
Journal Article -
14
Whole-Genome Cardiac DNA Methylation Fingerprint and Gene Expression Analysis Provide New Insights in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
Published in Clinical infectious diseases (01-10-2017)“…Background. Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects 10 million people worldwide. Approximately 12…”
Get full text
Journal Article -
15
Cardiac MicroRNA Expression Profile After Experimental Brain Death Is Associated With Myocardial Dysfunction and Can Be Modulated by Hypertonic Saline
Published in Transplantation (01-02-2022)“…Brain death (BD) is associated with systemic inflammatory compromise, which might affect the quality of the transplanted organs. This study investigated the…”
Get full text
Journal Article -
16
Circulating mir-208a fails as a biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients
Published in Journal of applied toxicology (01-09-2015)Get full text
Journal Article -
17
miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
Published in PLoS neglected tropical diseases (01-12-2020)“…Chronic Chagas disease cardiomyopathy (CCC), an especially aggressive inflammatory dilated cardiomyopathy caused by lifelong infection with the protozoan…”
Get full text
Journal Article -
18
Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction
Published in The Journal of infectious diseases (01-02-2017)“…Abstract Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects 7 million people in Latin American areas of endemicity. About 30% of…”
Get full text
Journal Article -
19
Brazil nut intake increases circulating miR-454-3p and miR-584-5p in obese women
Published in Nutrition research (New York, N.Y.) (01-07-2019)“…The Brazil nut is an excellent source of selenium (Se), an essential micronutrient for human health. In this study, we hypothesized that Brazil nut intake…”
Get full text
Journal Article -
20
Progression of Type 1 Diabetes: Circulating MicroRNA Expression Profiles Changes from Preclinical to Overt Disease
Published in Journal of immunology research (19-07-2022)“…Aims/Hypothesis. The role of microRNAs (miRNAs) in type 1 diabetes (T1D) pathogenesis and progression has been described but remains elusive. Objectives. To…”
Get full text
Journal Article