Search Results - "Rodrigues Abadio, Ana Karina"
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Selection of potential anti-adhesion drugs by in silico approaches targeted to ALS3 from Candida albicans
Published in Biotechnology letters (01-12-2019)“…Objective To select potential ligands of ALS3 for drug development with anti-adhesion and/or anti-biofilm activities. Methodology ALS3 model was considered…”
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Identification of New Antifungal Compounds Targeting Thioredoxin Reductase of Paracoccidioides Genus
Published in PloS one (16-11-2015)“…The prevalence of invasive fungal infections worldwide has increased in the last decades. The development of specific drugs targeting pathogenic fungi without…”
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Structural and functional characterization of the recombinant thioredoxin reductase from Candida albicans as a potential target for vaccine and drug design
Published in Applied microbiology and biotechnology (01-05-2016)“…The thioredoxin system plays a critical role in maintaining the cytoplasm redox state, participating in functions that are important to the cellular viability…”
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Antifungal drugs: New insights in research & development
Published in Pharmacology & therapeutics (Oxford) (01-03-2019)“…The need for better antifungal therapy is commonly accepted in view of the high mortality rates associated with systemic infections, the low number of…”
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One Century of Study: What We Learned about Paracoccidioides and How This Pathogen Contributed to Advances in Antifungal Therapy
Published in Journal of fungi (Basel) (02-02-2021)“…Paracoccidioidomycosis (PCM) is a notable fungal infection restricted to Latin America. Since the first description of the disease by Lutz up to the present…”
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Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site
Published in Biochemistry and biophysics reports (01-03-2020)“…An elevated prevalence of cryptococcal infection is a tendency in low-income countries and constitutes a global public health problem due to factors such as…”
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Mycovirus in Pseudocercospora griseola, the causal agent of angular leaf spot in common bean
Published in Canadian journal of microbiology (01-05-2010)“…Pseudocercospora griseola (Sacc.) Crous & Braun is a widespread fungal phytopathogen that is responsible for angular leaf spot in the common bean (Phaseolus…”
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Characterization of the Molecular Target KRE2 of Paraccocidioides lutzii Aiming at Development of New Antifungal Therapies
Published in Biophysical journal (02-02-2018)Get full text
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