Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial

Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial

Aim The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6–13 years using inferior alveolar nerve block. Methods A triple blinded randomized controlled trial was conducted in 180 participants (9...

Full description

Saved in:
Bibliographic Details
Published in:Clinical oral investigations Vol. 23; no. 9; pp. 3543 - 3550
Main Authors: Ramadurai, Neeraja, Gurunathan, Deepa, Samuel, A. Victor, Subramanian, Emg, Rodrigues, Steven J L
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-09-2019
Springer Nature B.V
Subjects:
Adolescent
Alveoli
Anesthesia
Anesthesia, Dental
Anesthetics, Local - therapeutic use
Carticaine - therapeutic use
Child
Children
Clinical trials
Dentistry
Female
Humans
Lidocaine
Male
Medicine
Nerve Block
Original Article
Pain
Randomized controlled trial
Articaine
Children
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6–13 years using inferior alveolar nerve block. Methods A triple blinded randomized controlled trial was conducted in 180 participants (90 patients- 2% articaine, 90 patients-2% lignocaine). Effectiveness of the anesthetic agent was determined at 3 points determined by subjective evaluation of pain using pain scales (FPS-R). Paired sample t-test and chi square test were performed for statistical significance. Result Anesthetic success for 2% articaine were 64.4%, 42.2% and 81.8% respectively. The anesthetic success of 2% lignocaine was 66.7%, 48.9% and 85.7% at point one, point two and point three respectively ( p  > 0.05). Conclusion This study concludes that 2% articaine in 1:2,00,000 did not demonstrate superior clinical effectiveness in comparison to 2% lignocaine. Clinical significance Lignocaine has always been considered the gold standard. With its unique chemical structure and increased potency, Articaine has been gaining popularity. Its efficacy in 2% concentration had not been compared to 2% lignocaine. 2% articaine did not show clinical superiority but its comparable effectiveness with lignocaine can encourage further research in using articaine in reduced concentrations to improve effectiveness.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
ISSN:1432-6981
1436-3771
DOI:10.1007/s00784-018-2775-5