Infectious endocarditis caused by Bartonella henselae associated with infected pets: two case reports

Blood culture-negative infective endocarditis is a potentially severe disease that can be associated with infectious agents such as Bartonella spp., Coxiella burnetti, Tropheryma whipplei, and some fungi. Reported here are two cases of blood culture-negative infective endocarditis in patients with s...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of medical case reports Vol. 17; no. 1; p. 143
Main Authors:	Gonçalves-Oliveira, Jonathan, Damasco, Paulo Vieira, Assis, Matheus Ribeiro da S, Freitas, Dominique E, Pessoa Junior, Adonai Alvino, de Sousa, Luiza S, Rodrigues, Nicollas G, Damasco, Paula H, Ribeiro, Pedro F, Barbosa, Giovanna F, Moreira, Namir S, Guedes, Jeferson F, Coutinho, Henrique M da Rocha, Madi, Kalil, de Lemos, Elba R Sampaio
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 19-04-2023 BioMed Central BMC
Subjects:	Anemia Animals Antibiotics Antibodies Bartonella Bartonella henselae Bartonella Infections - complications Bartonella Infections - diagnosis Bartonella Infections - microbiology Blood Case Report Case reports Cats Disease Dogs Drug use Endocarditis Endocarditis - complications Endocarditis, Bacterial - microbiology Epidemiology Hematuria Hospitals Humans Infections Infective endocarditis Laboratories Medical examination Medical research Microorganisms One Health Pets Veterinarians Zoonoses Brazil Rio de Janeiro Brazil Bartonella Pets Case report Endocarditis One Health
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Blood culture-negative infective endocarditis is a potentially severe disease that can be associated with infectious agents such as Bartonella spp., Coxiella burnetti, Tropheryma whipplei, and some fungi. Reported here are two cases of blood culture-negative infective endocarditis in patients with severe aortic and mitral regurgitation in Brazil; the first case is a 47-year-old white man and the second is a 62-year-old white woman. Bartonella henselae deoxyribonucleic acid was detectable in the blood samples and cardiac valve with vegetation paraffin-fixed tissue samples. Additionally, an investigation was carried out on patients' pets, within the context of One Health, and serum samples collected from cats and dogs were reactive by indirect immunofluorescence assay. Even though the frequency of bartonellosis in Brazil is unknown, physicians should be aware of the possibility of blood culture-negative infective endocarditis caused by Bartonella, particularly in patients with weight loss, kidney changes, and epidemiological history for domestic animals.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1752-1947 1752-1947
DOI:	10.1186/s13256-023-03839-8