High prevalence of antimicrobial drug-resistant diarrheagenic Escherichia coli in asymptomatic children living in an urban slum

High prevalence of antimicrobial drug-resistant diarrheagenic Escherichia coli in asymptomatic children living in an urban slum

Summary Purpose The aim of this study was to investigate the presence of diarrheagenic Escherichia coli and antibiotic resistance in asymptomatic school-age children living in an area with defective environmental sanitation, comparing with children registered at a private school, both in the city of...

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Bibliographic Details
Published in:The Journal of infection Vol. 59; no. 4; pp. 247 - 251
Main Authors: Souza, Tamara B, Morais, Mauro B, Tahan, Soraia, Melli, Ligia C.F.L, Rodrigues, Mirian S.C, Scaletsky, Isabel C.A
Format: Journal Article
Language:English
Published: Amsterdam Elsevier Ltd 01-10-2009
Elsevier
Subjects:
Anti-Bacterial Agents - therapeutic use
Antibiotic resistance
Asymptomatic children
Biological and medical sciences
Brazil - epidemiology
Child
Child, Preschool
Cities
Diarrhea - epidemiology
Diarrheagenic Escherichia coli
Drug Resistance, Bacterial
Escherichia coli
Escherichia coli - isolation & purification
Escherichia coli Infections - epidemiology
Feces - microbiology
Female
General aspects
Humans
Infectious Disease
Male
Medical sciences
Microbial Sensitivity Tests
Population
Poverty Areas
Prevalence
Virulence Factors - analysis
Brazil
Diarrheagenic Escherichia coli
Asymptomatic children
Antibiotic resistance
Human
Infection
Resistance
Urban environment
Prevalence
Escherichia coli
Bacteria
Asymptomatic
Epidemiology
Child
Antimicrobial agent
Enterobacteriaceae
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Summary:Summary Purpose The aim of this study was to investigate the presence of diarrheagenic Escherichia coli and antibiotic resistance in asymptomatic school-age children living in an area with defective environmental sanitation, comparing with children registered at a private school, both in the city of Osasco, Brazil. Methods Seventy-nine school-age children between 5 and 10 years living in a slum and 35 children who attended a private school of the same city were included in the study. Results DEC was found in 58% of the children living in the slum and in 17% of the control group ( P = 0.001). Resistance to at least one antimicrobial drug was found in 65% of DEC strains; resistant to two or more antimicrobial drugs was found in 46% of strains. Conclusion The high carriage status among the slum children point towards the widespread environment contamination in low socio-economic housing conditions, in conformance with the pediatric population at higher risk for developing DEC diarrhea.
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ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2009.08.007