Factors influencing possible delay in the diagnosis of Alzheimer's disease: Findings from a tertiary Public University Hospital

Alzheimer's disease (AD) is characterized by impairment in memory and autonomy, causing excessive pressure on family and an overburdened health care system. Early diagnosis, with the appropriate treatment, is important to reduce the pattern of disease progression. The study sought to identify t...

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Published in:Dementia & neuropsychologia Vol. 5; no. 4; pp. 328 - 331
Main Authors: de Miranda, Luís Felipe José Ravic, Matoso, Rafael de Oliveira, Rodrigues, Márlon Vieira, de Lima, Thiago Oliveira Lemos, Nascimento, Adriano Fiorini, Carvalho, Fernando Castro, Moreira, Débora Regina de Melo, Fernandes, Jeferson Cruz, de Paula, Jonas Jardim, Magno, Luiz Alexandre V, Caramelli, Paulo, de Moraes, Edgar Nunes
Format: Journal Article
Language:English
Published: Brazil Associação de Neurologia Cognitiva e do Comportamento 01-12-2011
Associação Neurologia Cognitiva e do Comportamento
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Summary:Alzheimer's disease (AD) is characterized by impairment in memory and autonomy, causing excessive pressure on family and an overburdened health care system. Early diagnosis, with the appropriate treatment, is important to reduce the pattern of disease progression. The study sought to identify the most probable causes of delay in diagnosis. A cross-sectional study involving AD patients followed at an Outpatient Geriatric Clinic from a tertiary public university hospital was conducted between June 2009 and February 2011. Ninety-four patients were evaluated (66% women), aged 77.76±6.8 years and with median educational level of 3 years (95% CI 2.7-3.80). Regarding severity of dementia, 51.8% of patients were classified as having mild dementia (CDR 1), 40% moderate dementia (CDR 2) and 8.2% severe dementia (CDR 3). Mean educational level of caregivers was 8.3±3.9 years. Among those who believed there was a delay, 36% stated that the "family thought that the changes were normal for the age of the patient" reporting average delay of 1.8 years (95% CI: 1.3-2.5) while 45.3% stated that the "doctor did not reach a diagnosis" reporting a median delay of 1.5 years (95% CI: 1.4-2.3). Based on these results, it can be concluded the time between onset of symptoms and diagnosis was excessive. This study may be useful to help increase awareness of issues not sufficiently discussed in the literature, such as diagnostic delay and influence of caregivers' educational level on treatment.
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ISSN:1980-5764
1980-5764
DOI:10.1590/S1980-57642011DN05040011