Search Results - "Rodrigues, Loreta M"

Tumor R2 is a prognostic indicator of acute radiotherapeutic response in rodent tumors by Rodrigues, Loreta M., Howe, Franklyn A., Griffiths, John R., Robinson, Simon P.

“…Purpose To test the prognostic potential of tumor R2* with respect to radiotherapeutic outcome. Blood oxygenation level dependent (BOLD) MRI images are…”
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Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy by Rodrigues, Loreta M, Chung, Yuen-Li, Al Saffar, Nada M S, Sharp, Swee Y, Jackson, Laura E, Banerji, Udai, Stubbs, Marion, Leach, Martin O, Griffiths, John R, Workman, Paul

“…The importance of ERBB2/NEU/HER2 in the response of breast tumours to the heat shock protein 90 (HSP90) inhibitor 17-allylamino-17-demethoxygeldanamycin…”
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The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox by Rodrigues, Loreta M, Uribe-Lewis, Santiago, Madhu, Basetti, Honess, Davina J, Stubbs, Marion, Griffiths, John R

“…Ketone bodies have both metabolic and epigenetic roles in cancer. In several studies, they showed an anti-cancer effect via inhibition of histone deacetylases;…”
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In vivo hyperpolarized 129Xe NMR spectroscopy in tumors by Wolber, Jan, McIntyre, Dominick J.O., Rodrigues, Loreta M., Carnochan, Paul, Griffiths, John R., Leach, Martin O., Bifone, Angelo

“…The first in vivo hyperpolarized 129Xe NMR study in experimental tumors is presented. Hyperpolarized 129Xe was dissolved in solutions, and was injected…”
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Enhanced Uptake of Ifosfamide into GH3 Prolactinomas with Hypercapnic Hyperoxic Gases Monitored In Vivo by 31P MRS by Rodrigues, Loreta M., Robinson, Simon P., McSheehy, Paul M.J., Stubbs, Marion, Griffiths, John R.

“…Previously, 31P magnetic resonance spectroscopy (MRS) has been used to detect ifosfamide (IF) in vivo and to show that breathing carbogen (5% CO2/95% O2)…”
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Response of Hepatoma 9618a and Normal Liver to Host Carbogen and Carbon Monoxide Breathing by Robinson, Simon P., Rodrigues, Loreta M., Griffiths, John R., Stubbs, Marion

“…The effects of hyperoxia (induced by host carbogen 95% oxygen/5% carbon dioxide breathing. and hypoxia (induced by host carbon monoxide CO at 660 ppm…”
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In vivo 31P magnetic resonance spectroscopy using a needle microcoil by Howe, Franklyn A., Syms, Richard R.A., Ahmad, Munir M., Rodrigues, Loreta M., Griffiths, John R., Young, Ian R.

“…Batch fabrication methods have been used to produce low‐cost microcoils for magnetic resonance spectroscopy (MRS) that could be discarded after applications…”
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Effects of different levels of hypercapnic hyperoxia on tumour R2 and arterial blood gases by ROBINSON, Simon P, RODRIGUES, Loreta M, HOWE, Franklyn A, STUBBS, Marion, GRIFFITHS, John R

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Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS by Rodrigues, Loreta M, Robinson, Simon P, McSheehy, Paul M J, Stubbs, Marion, Griffiths, John R

“…Previously, (31)P magnetic resonance spectroscopy (MRS) has been used to detect ifosfamide (IF) in vivo and to show that breathing carbogen (5% CO(2)/95% O(2))…”
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Issues in GRE & SE magnetic resonance imaging to probe tumor oxygenation by Howe, Franklyn A, Robinson, Simon P, Rodrigues, Loreta M, Stubbs, Marion, Griffiths, John R

“…Tumor oxygenation determines the efficacy of radiotherapy, but there is no non-invasive way to image this parameter. Since gradient recalled echo (GRE) images…”
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Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment by Griffiths, J R, McIntyre, D J, Howe, F A, McSheehy, P M, Ojugo ASE, Rodrigues, L M, Wadsworth, P, Price, N M, Lofts, F, Nicholson, G, Smid, K, Noordhuis, P, Peters, G J, Stubbs, M

“…Non-invasive magnetic resonance spectroscopy (MRS) can be used in the clinic to monitor the pharmacokinetics of the chemotherapeutic drug 5-fluorouracil (5-FU)…”
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Tumor R 2 is a prognostic indicator of acute radiotherapeutic response in rodent tumors by Rodrigues, Loreta M., Howe, Franklyn A., Griffiths, John R., Robinson, Simon P.

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In vivo 31 P magnetic resonance spectroscopy using a needle microcoil by Howe, Franklyn A., Syms, Richard R.A., Ahmad, Munir M., Rodrigues, Loreta M., Griffiths, John R., Young, Ian R.

“…Batch fabrication methods have been used to produce low‐cost microcoils for magnetic resonance spectroscopy (MRS) that could be discarded after applications…”
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In vivo determination of tumor oxygenation during growth and in response to carbogen breathing using 15C5-loaded alginate capsules as fluorine-19 magnetic resonance imaging oxygen sensors by Nöth, Ulrike, Rodrigues, Loreta M, Robinson, Simon P, Jork, Anette, Zimmermann, Ulrich, Newell, Barry, Griffiths, John R

“…The objective was to present a method for the repeated noninvasive measurement of tumor oxygenation (Po(2)) over the whole period of tumor growth. A mixture of…”
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Rapid stimulation by vasopressin, oxytocin and angiotensin II of glycogen degradation in hepatocyte suspensions by Hems, D A, Rodrigues, L M, Whitton, P D

“…1. The hormonal control of glycogen breakdown was studied in hepatocytes isolated from livers of fed rats. 2. Glucose release was stimulated by…”
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The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents that improve tumor oxygenation by Stubbs, Marion, Robinson, Simon P, Hui, Chuk, Price, Natasha M, Rodrigues, Loreta M, Howe, Franklyn A, Griffiths, John R

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Effects of different levels of hypercapnic hyperoxia on tumour R 2 ∗ and arterial blood gases by Robinson, Simon P., Rodrigues, Loreta M., Howe, Franklyn A., Stubbs, Marion, Griffiths, John R.

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Tumour response to hypercapnia and hyperoxia monitored by FLOOD magnetic resonance imaging by Robinson, Simon P., Collingridge, David R., Howe, Franklyn A., Rodrigues, Loreta M., Chaplin, David J., Griffiths, John R.

“…Flow and oxygenation dependent (FLOOD) MR images of GH3 prolactinomas display large intensity increases in response to carbogen (5% CO2/95% O2) breathing. To…”
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Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow by Robinson, Simon P., Howe, Franklyn A., Rodrigues, Loreta M., Stubbs, Marion, Griffiths, John R.

“…The application of functional magnetic resonance (MR) imaging techniques to the measurement of oxygenation and blood flow in tumors is described. Gradient…”
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Assessment of induced rat mammary tumour response to chemotherapy using the apparent diffusion coefficient of tissue water as determined by diffusion-weighted H-NMR spectroscopy in vivo by LEMAIRE, L, HOWE, F, RODRIGUES, L, GRIFFITHS, J

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