Search Results - "Rodrigues, João M.O.S."
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The breakdown of the word symmetry in the human genome
Published in Journal of theoretical biology (21-10-2013)“…Previous studies have suggested that Chargaff's second rule may hold for relatively long words (above 10nucleotides), but this has not been conclusively shown…”
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DNA word analysis based on the distribution of the distances between symmetric words
Published in Scientific reports (07-04-2017)“…We address the problem of discovering pairs of symmetric genomic words (i.e., words and the corresponding reversed complements) occurring at distances that are…”
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The exceptional genomic word symmetry along DNA sequences
Published in BMC bioinformatics (03-02-2016)“…The second Chargaff's parity rule and its extensions are recognized as universal phenomena in DNA sequences. However, parity of the frequencies of reverse…”
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Analysis of single-strand exceptional word symmetry in the human genome: new measures
Published in Biostatistics (Oxford, England) (01-04-2015)“…Some previous studies suggest the extension of Chargaff's second rule (the phenomenon of symmetry in a single DNA strand) to long DNA words. However, in random…”
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On finding minimal absent words
Published in BMC bioinformatics (08-05-2009)“…The problem of finding the shortest absent words in DNA data has been recently addressed, and algorithms for its solution have been described. It has been…”
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XS: a FASTQ read simulator
Published in BMC research notes (2014)“…The emerging next-generation sequencing (NGS) is bringing, besides the natural huge amounts of data, an avalanche of new specialized tools (for analysis,…”
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Distribution of Distances Between Symmetric Words in the Human Genome: Analysis of Regular Peaks
Published in Interdisciplinary sciences : computational life sciences (01-09-2019)“…Finding DNA sites with high potential for the formation of hairpin/cruciform structures is an important task. Previous works studied the distances between…”
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Minimal absent words in prokaryotic and eukaryotic genomes
Published in PloS one (31-01-2011)“…Minimal absent words have been computed in genomes of organisms from all domains of life. Here, we explore different sets of minimal absent words in the…”
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Exceptional Symmetry by Genomic Word: A Statistical Analysis
Published in Interdisciplinary sciences : computational life sciences (01-03-2017)“…Single-strand DNA symmetry is pointed as a universal law observed in the genomes from all living organisms. It is a somewhat broadly defined concept, which has…”
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Exceptional single strand DNA word symmetry: analysis of evolutionary potentialities
Published in Journal of integrative bioinformatics (01-12-2014)“…Some previous studies point to the extension of Chargaff’s second rule (the phenomenon of symmetry) to words of large length. However, in random sequences…”
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Inter-dinucleotide distances in the human genome: an analysis of the whole-genome and protein-coding distributions
Published in Journal of integrative bioinformatics (01-12-2011)“…We study the inter-dinucleotide distance distributions in the human genome, both in the whole-genome and protein-coding regions. The inter-dinucleotide…”
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