Search Results - "Rodrigues, Felipe A R"

Cytotoxic profile of natural and some modified bufadienolides from toad Rhinella schneideri parotoid gland secretion by Cunha-Filho, Geraldino A., Resck, Inês S., Cavalcanti, Bruno C., Pessoa, Cláudia Ó., Moraes, Manoel O., Ferreira, José R.O., Rodrigues, Felipe A.R., dos Santos, Maria L.

“…Cutaneous secretions of toad species are an important source of bufadienolides, compounds that exhibit interesting structural features and biopharmacological…”
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Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: Cancer cell growth inhibition, ROS production and hemolytic activity by de Oliveira, Alane Cabral, Hillard, Elizabeth A., Pigeon, Pascal, Rocha, Danilo Damasceno, Rodrigues, Felipe A.R., Montenegro, Raquel C., Costa-Lotufo, Letícia V., Goulart, Marilia O.F., Jaouen, Gérard

“…The antiproliferative effects of twenty-eight tetrasubstituted olefins bearing a ferrocenyl group, including six never-reported compounds, were evaluated…”
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Mefloquine-Oxazolidine Derivatives: A New Class of Anticancer Agents by Rodrigues, Felipe A. R., Bomfim, Igor da S., Cavalcanti, Bruno C., Pessoa, Claudia, Goncalves, Raoni S. B., Wardell, James L., Wardell, Solange M. S. V., de Souza, Marcus V. N.

“…A series of 23 racemic mefloquine–oxazolidine derivatives, 4‐[3‐(aryl)hexahydro[1,3]oxazolo[3,4‐a]pyridin‐1‐yl]‐2,8‐bis(trifluoromethyl)quinolines, derived…”
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Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative Escherichia coli by Carvalho, Eunice B, Maga, Elizabeth A, Quetz, Josiane S, Lima, Ila F N, Magalhães, Hemerson Y F, Rodrigues, Felipe A R, Silva, Antônio V A, Prata, Mara M G, Cavalcante, Paloma A, Havt, Alexandre, Bertolini, Marcelo, Bertolini, Luciana R, Lima, Aldo A M

“…Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by…”
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Structure Elucidation, Antimicrobial and Cytotoxic Activities of a Halimane Isolated from Vellozia kolbekii Alves (Velloziaceae) by Silva, Carmelita G., Santos Júnior, Helvécio M., Barbosa, Jussara P., Costa, Gisela L., Rodrigues, Felipe A. R., Oliveira, Denilson F., Costa-Lotufo, Letícia V., Alves, Ruy J. V., Eleutherio, Elis C. A., Rezende, Claudia M.

“…A new halimane diterpene was isolated from Vellozia kolbekii Alves (Velloziaceae) and identified as (5R,8R,9S,13R)‐halim‐1,10‐ene‐15,16‐diol (1). It showed…”
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Design, synthesis and biological evaluation of (E)-2-(2-arylhydrazinyl)quinoxalines, a promising and potent new class of anticancer agents by Rodrigues, Felipe A.R., Bomfim, Igor da S., Cavalcanti, Bruno C., Pessoa, Claudia do Ó., Wardell, James L., Wardell, Solange M.S.V., Pinheiro, Alessandra C., Kaiser, Carlos Roland, Nogueira, Thais C.M., Low, John N., Gomes, Ligia R., de Souza, Marcus V.N.

“…A series of forty-seven quinoxaline derivatives, 2-(XYZC6H2CHN–NH)-quinoxalines, 1, have been synthesized and evaluated for their activity against four cancer…”
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Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis by Neto, João B A, da Silva, Cecília R, Neta, Maria A S, Campos, Rosana S, Siebra, Janaína T, Silva, Rose A C, Gaspar, Danielle M, Magalhães, Hemerson I F, de Moraes, Manoel O, Lobo, Marina D P, Grangeiro, Thalles B, Carvalho, Tatiane S C, Diogo, Emilay B T, da Silva Júnior, Eufrânio N, Rodrigues, Felipe A R, Cavalcanti, Bruno C, Júnior, Hélio V N

“…In recent decades, the incidence of candidemia in tertiary hospitals worldwide has substantially increased. These infections are a major cause of morbidity and…”
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N-acylhydrazones containing thiophene nucleus: a new anticancer class by Cardoso, Laura N. F., Nogueira, Thais C. M., Rodrigues, Felipe A. R., Oliveira, Augusto Cesar Aragão, Luciano, Maria Claudia dos Santos, Pessoa, Claudia, de Souza, Marcus V. N.

“…In this study, we present a series of N -acylhydrazones containing thiophene nuclei as a new anticancer class. Fifty-seven compounds in this series were…”
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A new and potent class of quinoline derivatives against cancer by Bispo, Marcelle de L. F., de Alcantara, Camila C., de Moraes, Manoel O., do Ó Pessoa, Cláudia, Rodrigues, Felipe A. R., Kaiser, Carlos R., Wardell, Solange M. S. V., Wardell, James L., de Souza, Marcus V. N.

“…A new class of 4-quinolinylhydrazone derivatives has been synthesized and evaluated for their cytotoxic potential against three cancer cell lines using the MTT…”
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Biological evaluation of isoniazid derivatives as an anticancer class by Rodrigues, Felipe A R, Oliveira, Augusto C A, Cavalcanti, Bruno C, Pessoa, Claudia, Pinheiro, Alessandra C, de Souza, Marcus V N

“…A series of thirty-two isoniazid derivatives have been evaluated for their activity against four human cancer cell lines with potent cytotoxicity (IC50 ranging…”
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Molecular Mechanism of Action of 2-Ferrocenyl-1,1-diphenylbut-1-ene on HL-60 Leukemia Cells by de Oliveira, Alane Cabral, da Silva, Emanuella Gomes, Rocha, Danilo Damasceno, Hillard, Elizabeth A., Pigeon, Pascal, Jaouen, Gérard, Rodrigues, Felipe A. R., de Abreu, Fabiane C., da Rocha Ferreira, Fabrícia, Goulart, Marilia O. F., Costa-Lotufo, Letícia V.

“…The aim of this work was to investigate the mechanism of action of 2‐ferrocenyl‐1,1‐diphenylbut‐1‐ene (1) on HL‐60 human leukemia cells. While inactive against…”
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Cytotoxic Activity of Fungal Strains Isolated from the Ascidian Eudistoma vannamei by Montenegro, Tasso G. C., Rodrigues, Felipe A. R., Jimenez, Paula C., Angelim, Alysson L., Melo, Vânia M. M., Rodrigues Filho, Edson, de Oliveira, Maria da Conceição F., Costa-Lotufo, Letícia V.

“…The cytotoxic activity at 50 μg/ml of extracts obtained from eleven fungal strains associated to Eudistoma vannamei, an endemic ascidian from Northeast Brazil,…”
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Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H2O2-induced DNA damage in cultured human leukocytes by Cavalcanti, Bruno C., Ferreira, José R.O., Cabral, Igor O., Magalhães, Hemerson I.F., de Oliveira, Cecília C., Rodrigues, Felipe A.R., Rocha, Danilo D., Barros, Francisco W.A., da Silva, Cecília R., Júnior, Hélio V.N., Canuto, Kirley M., Silveira, Edilberto R., Pessoa, Cláudia, Moraes, Manoel O.

“…► Essential oil (EO) of Alpinia zerumbet did not induce genetic toxicity in human leukocytes. ► EO did not exert any mutagenic effects on peripheral blood…”
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Involvement of intrinsic mitochondrial pathway in neosergeolide-induced apoptosis of human HL-60 leukemia cells: the role of mitochondrial permeability transition pore and DNA damage by Cavalcanti, Bruno C, da Costa, Patrícia M, Carvalho, Adriana A, Rodrigues, Felipe A R, Amorim, Rodrigo C N, Silva, Ellen C C, Pohlit, Adrian M, Costa-Lotufo, Letícia V, Moraes, Manoel O, Pessoa, Cláudia

“…Quassinoids are biologically active secondary metabolites found exclusively in the Simaroubaceae family of plants. These compounds generally present important…”
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Studies on the Secondary Metabolites of a Pseudoalteromonas sp. Isolated from Sediments Collected at the Northeastern Coast of Brazil by Arthaud, Isabelle D. B., Rodrigues, Felipe A. R., Jimenez, Paula C., Montenegro, Raquel C., Angelim, Alysson L., Maciel, Vânia M. M., Silveira, Edilberto R., Freitas, Hozana P. S., Sousa, Thiciana S., Pessoa, Otília D. L., Lotufo, Tito M. C., Costa-Lotufo, Letícia V.

“…Continuing search for anticancer compounds from the marine environment, we have studied microorganisms that inhabit intertidal sediments of the northeastern…”
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Potent antileukemic action of naphthoquinoidal compounds: evidence for an intrinsic death mechanism based on oxidative stress and inhibition of DNA repair by Cavalcanti, Bruno C., Cabral, Igor O., Rodrigues, Felipe A. R., Barros, Francisco W. A., Rocha, Danilo D., Magalhães, Hemerson I. F., Moura, Dinara J., Saffi, Jenifer, Henriques, João A. P., Carvalho, Tatiane S. C., Moraes, Manoel O., Pessoa, Cláudia, Melo, Isadora M. M. de, Silva Júnior, Eufrânio N. da

“…The current study describes that nor-β-lapachone and its arylamino derivatives, iodinated and methylated naphthoquinones and nor-β-lapachone-based…”
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Evaluation of (2S,3R)-2-(amino)-[4-(N-benzylarenesulfonamido)-3-hydroxy-1-phenylbutane derivatives: a promising class of anticancer agents by Facchinetti, Victor, Moreth, Marcele, Gomes, Claudia R. B., do Ó Pessoa, Cláudia, Rodrigues, Felipe A. R., Cavalcanti, Bruno C., Oliveira, Augusto C. A., Carneiro, Teiliane R., Gama, Ivson Lelis, de Souza, Marcus V. N.

“…Twenty-two hydroxyethylamine derivatives ((2 S ,3 R )-2-(Amino)-[4-( N -benzylarenesulfonamido)-3-hydroxy-1-phenylbutane derivatives) containing aromatic…”
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In vitro studies on Bothrops venoms cytotoxic effect on tumor cells by Jorge, Roberta J B, Martins, Alice M C, Morais, Isabel C O, Ximenes, Rafael M, Rodrigues, Felipe A R, Soares, Bruno M, Evangelista, Janaina S A M, Toyama, Marcos H, Martins, Aline M A, Moraes Filho, Manoel O, Monteiro, Helena S A

“…Animal venoms are complex mixtures of proteins and non proteins components with several biological activities. Snake venoms represent an essentially unexplored…”
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Blainvillea rhomboidea: constituintes químicos e atividade citotóxica by Gomes, Regina Ferreira, Santos, Hélcio Silva dos, Albuquerque, Maria Rose Jane R., Pessoa, Otília Deusdênia L., Lotufo, Leticia V. Costa, Pessoa, Claudia do Ó, Moraes, Manoel Odorico de, Rodrigues, Felipe A. R.

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Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity by Regina Ferreira Gomes, Hélcio Silva dos Santos, Maria Rose Jane R. Albuquerque, Otília Deusdênia L. Pessoa, Leticia V. Costa Lotufo, Claudia do Ó Pessoa, Manoel Odorico de Moraes, Felipe A. R. Rodrigues

“…The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and…”
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