Search Results - "Rodrigues, Claudia O"
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Micro- and Macrovascular Complications in Diabetes Mellitus: Preclinical and Clinical Studies
Published in Journal of diabetes research (01-01-2019)“…Collectively, gender differences may be taken into account when providing healthcare management and allocate resources for prevention and treatment of…”
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Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia
Published in Respiratory research (12-07-2017)“…Mesenchymal stem cells (MSCs) attenuate lung injury in experimental models of bronchopulmonary dysplasia (BPD). Stromal derived factor-1 (SDF-1), a chemokine…”
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Protective role of CXCR7 activation in neonatal hyperoxia-induced systemic vascular remodeling and cardiovascular dysfunction in juvenile rats
Published in Scientific reports (09-11-2023)“…Neonatal hyperoxia induces long-term systemic vascular stiffness and cardiovascular remodeling, but the mechanisms are unclear. Chemokine receptor 7 (CXCR7)…”
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S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2013)“…Although nitric oxide (NO) signaling promotes differentiation and maturation of endothelial progenitor cells, its role in the differentiation of mesenchymal…”
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Stem Cell Applications in Regenerative Medicine for Kidney Diseases
Published in Stem cells international (01-01-2021)“…Overall, CKD is mainly caused by diabetic kidney disease (DKD), hypertension, and glomerulonephritis. [...]the search for nonpharmacological strategies for…”
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Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration
Published in American journal of physiology. Heart and circulatory physiology (01-12-2016)“…Cardiac stem cells (CSCs) are being evaluated for their efficacy in the treatment of heart failure. However, numerous factors impair the exogenously delivered…”
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Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival
Published in Proceedings of the National Academy of Sciences - PNAS (02-12-2014)“…The beneficial effects of agonists of growth hormone-releasing hormone receptor (GHRH-R) in heart failure models are associated with an increase in the number…”
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c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype
Published in PloS one (06-09-2013)“…The proto-oncogene c-Myc is vital for vascular development and promotes tumor angiogenesis, but the mechanisms by which it controls blood vessel growth remain…”
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Endothelial Mesenchymal Transition: Comparative Analysis of Different Induction Methods
Published in Biological procedures online (27-04-2016)“…Endothelial-Mesenchymal-Transition (EndMT) plays an essential role in cardiovascular development, and recently became an attractive therapeutic target based on…”
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Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI)
Published in Proceedings of the National Academy of Sciences - PNAS (10-01-2012)“…Both cardiac myocytes and cardiac stem cells (CSCs) express the receptor of growth hormone releasing hormone (GHRH), activation of which improves injury…”
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c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation
Published in Frontiers in cell and developmental biology (28-02-2024)“…Intra-amniotic inflammation (IAI) is associated with increased risk of preterm birth and bronchopulmonary dysplasia (BPD), but the mechanisms by which IAI…”
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Endothelial c-Myc knockout disrupts metabolic homeostasis and triggers the development of obesity
Published in Frontiers in cell and developmental biology (19-07-2024)“…Obesity is a major risk factor associated with multiple pathological conditions including diabetes and cardiovascular disease. Endothelial dysfunction is an…”
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Bone marrow-derived c-kit+ cells attenuate neonatal hyperoxia-induced lung injury
Published in Cell transplantation (01-01-2015)“…Recent studies suggest that bone marrow (BM)-derived stem cells have therapeutic efficacy in neonatal hyperoxia-induced lung injury (HILI). c-kit, a tyrosine…”
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MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300
Published in PloS one (13-11-2013)“…To characterize downstream effectors of p300 acetyltransferase in the myocardium. Acetyltransferase p300 is a central driver of the hypertrophic response to…”
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Identification of Organelles in Bacteria Similar to Acidocalcisomes of Unicellular Eukaryotes
Published in The Journal of biological chemistry (08-08-2003)“…Acidocalcisomes are acidic calcium storage compartments described in several unicellular eukaryotes, including trypanosomatid and apicomplexan parasites,…”
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Jun Kinase Delays Caspase-9 Activation by Interaction with the Apoptosome
Published in The Journal of biological chemistry (13-07-2007)“…Activation of c-Jun N-terminal kinase 1/2 (JNK) can delay oxidant-induced cell death, but the mechanism is unknown. We found that oxidant stress of cardiac…”
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Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells
Published in PloS one (24-08-2011)“…The adult myocardium has been reported to harbor several classes of multipotent progenitor cells (CPCs) with tri-lineage differentiation potential. It is not…”
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A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development
Published in Development (Cambridge) (01-06-2008)“…Myc -deficient mice fail to develop normal vascular networks and Myc -deficient embryonic stem cells fail to provoke a tumor angiogenic response when injected…”
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A Vacuolar-type H+-Pyrophosphatase Governs Maintenance of Functional Acidocalcisomes and Growth of the Insect and Mammalian Forms of Trypanosoma brucei
Published in The Journal of biological chemistry (04-10-2002)“…Vacuolar proton pyrophosphatases (V-H+-PPases) are electrogenic proton pumps found in many organisms of considerable industrial, environmental, and clinical…”
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Endothelial c‐Myc knockout enhances diet‐induced liver inflammation and fibrosis
Published in The FASEB journal (01-01-2022)“…Endothelial cells play an essential role in inflammation through synthesis and secretion of chemoattractant cytokines and expression of adhesion molecules…”
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