Search Results - "Rodrigues, Armanda"

Editorial: Neglected tropical diseases: tackling the challenges of a global world by Rodrigues, Armanda, Santos-Gomes, Gabriela

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A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies by Serras, Ana S, Rodrigues, Joana S, Cipriano, Madalena, Rodrigues, Armanda V, Oliveira, Nuno G, Miranda, Joana P

“…The poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical,…”
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Chagas Disease: A Silent Threat for Dogs and Humans by Durães-Oliveira, João, Palma-Marques, Joana, Moreno, Cláudia, Rodrigues, Armanda, Monteiro, Marta, Alexandre-Pires, Graça, da Fonseca, Isabel Pereira, Santos-Gomes, Gabriela

“…Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a flagellate protozoan, , that affects various mammalian species across…”
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Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity by Nunes, Sofia C., Ramos, Cristiano, Lopes-Coelho, Filipa, Sequeira, Catarina O., Silva, Fernanda, Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Guimarães, António, Silveira, Margarida, Abreu, Sofia, Santo, Vítor E., Brito, Catarina, Félix, Ana, Pereira, Sofia A., Serpa, Jacinta

“…Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and…”
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Meglumine Antimoniate and Miltefosine Combined With Allopurinol Sustain Pro-inflammatory Immune Environments During Canine Leishmaniosis Treatment by Santos, Marcos Ferreira, Alexandre-Pires, Graça, Pereira, Maria A., Marques, Cátia S., Gomes, Joana, Correia, Jorge, Duarte, Ana, Gomes, Lídia, Rodrigues, Armanda V., Basso, Alexandra, Reisinho, Ana, Meireles, José, Santos-Mateus, David, Brito, Maria Teresa Villa, Tavares, Luís, Santos-Gomes, Gabriela M., da Fonseca, Isabel Pereira

“…Canine leishmaniosis (CanL) caused by Leishmania infantum is a zoonotic disease of global concern. Antileishmanial drug therapies commonly used to treat sick…”
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Hemisynthetic trifluralin analogues incorporated in liposomes for the treatment of leishmanial infections by Carvalheiro, Manuela, Esteves, M. Alexandra, Santos-Mateus, David, Lopes, Rui M., Rodrigues, M. Armanda, Eleutério, Carla V., Scoulica, Effie, Santos-Gomes, Gabriela, Cruz, M. Eugénia M.

“…[Display omitted] Leishmaniasis, a vector-borne parasitic disease caused by Leishmania protozoa, is one of the most neglected tropical diseases in terms of…”
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Kupffer Cells and Hepatocytes: A Key Relation in the Context of Canine Leishmaniasis by Rodrigues, Armanda, Alexandre-Pires, Graça, Valério-Bolas, Ana, Nunes, Telmo, Pereira da Fonseca, Isabel, Santos-Gomes, Gabriela

“…Human zoonotic visceral leishmaniasis (ZVL) and canine leishmaniasis (CanL) constitute a major public and veterinary health concern and are both caused by the…”
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Exploiting Leishmania -Primed Dendritic Cells as Potential Immunomodulators of Canine Immune Response by Valério-Bolas, Ana, Meunier, Mafalda, Palma-Marques, Joana, Rodrigues, Armanda, Santos, Ana Margarida, Nunes, Telmo, Ferreira, Rui, Armada, Ana, Alves, João Carlos, Antunes, Wilson, Cardoso, Inês, Mesquita-Gabriel, Sofia, Lobo, Lis, Alexandre-Pires, Graça, Marques, Luís, Pereira da Fonseca, Isabel, Santos-Gomes, Gabriela

“…Dendritic cells (DCs) capture pathogens and process antigens, playing a crucial role in activating naïve T cells, bridging the gap between innate and acquired…”
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3D-Hepatocyte Culture Applied to Parasitology: Immune Activation of Canine Hepatic Spheroids Exposed to Leishmania infantum by Rodrigues, Armanda V, Alexandre-Pires, Graça, Valério-Bolas, Ana, Santos-Mateus, David, Rafael-Fernandes, Mariana, Pereira, Maria A, Ligeiro, Dário, Nunes, Telmo, Alves-Azevedo, Raquel, Santos, Marcos, Pereira da Fonseca, Isabel, Santos-Gomes, Gabriela

“…The application of innovative three-dimensional (3D) spheroids cell culture strategy to Parasitology offers the opportunity to closely explore host-parasite…”
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Immunophenotyping of Peripheral Blood, Lymph Node, and Bone Marrow T Lymphocytes During Canine Leishmaniosis and the Impact of Antileishmanial Chemotherapy by Santos, Marcos Ferreira, Alexandre-Pires, Graça, Pereira, Maria A., Gomes, Lídia, Rodrigues, Armanda V., Basso, Alexandra, Reisinho, Ana, Meireles, José, Santos-Gomes, Gabriela M., Pereira da Fonseca, Isabel

“…Dogs are a major reservoir of Leishmania infantum , etiological agent of canine leishmaniosis (CanL) a zoonotic visceral disease of worldwide concern…”
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Extending hepatocyte functionality for drug-testing applications using high-viscosity alginate-encapsulated three-dimensional cultures in bioreactors by Miranda, Joana P, Rodrigues, Armanda, Tostões, Rui M, Leite, Sofia, Zimmerman, Heiko, Carrondo, Manuel J T, Alves, Paula M

“…The maintenance of differentiated hepatocyte phenotype in vitro depends on several factors-in particular, on extracellular matrix interactions, for example,…”
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A building automation case study setup and challenges by Cambeiro, João, Gomes, Cláudio, Amaral, Vasco, Rodrigues, Armanda, Cunha, Jácome

“…Smart buildings will play a fundamental role in ensuring comfort while reducing the energy required. However, due to the lack of knowledge about the operation…”
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Insights on Host-Parasite Immunomodulation Mediated by Extracellular Vesicles of Cutaneous Leishmania shawi and Leishmania guyanensis by Weber, Juliana Inês, Rodrigues, Armanda Viana, Valério-Bolas, Ana, Nunes, Telmo, Carvalheiro, Manuela, Antunes, Wilson, Alexandre-Pires, Graça, da Fonseca, Isabel Pereira, Santos-Gomes, Gabriela

“…Leishmaniasis is a parasitic disease caused by different species of and transmitted through the bite of sand flies vector. Macrophages (MΦ), the target cells…”
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Zoonotic visceral leishmaniasis : new insights on innate immune response by blood macrophages and liver kupffer cells to leishmania infantum parasites by Rodrigues, Armanda Viana, Valerio-Bolas, Ana, Pires de Melo, Graça, Aires Pereira, Maria, Landeiro Raposo Pina Nunes, Telmo Renato, Ligeiro, Dario, Soares Pereira da Fonseca de Sampaio, Isabel Maria, Santos-Gomes, Gabriela

“…Research Areas: Life Sciences & Biomedicine L. infantum is the aetiological agent of zoonotic visceral leishmaniasis (ZVL), a disease that affects humans and…”
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Dam-Break Flood Emergency Management System by Rodrigues, A S, Santos, M A, Santos, A D, Rocha, F

“…Natural or induced floods are of increasing concern to watermanagers and civil protection services for three main reasons.Firstly, a continuous and…”
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Glycidamide and cis-2-butene-1,4-dial (BDA) as potential carcinogens and promoters of liver cancer - An in vitro study by Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Nunes, Carolina, Charneira, Catarina, Nunes, João, Serpa, Jacinta, Antunes, Alexandra M.M.

“…Acrylamide and furan are environmental and food contaminants that are metabolized by cytochrome P450 2E1 (CYP2E1), giving rise to glycidamide and…”
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Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy by Mendes, Cindy, Lopes-Coelho, Filipa, Ramos, Cristiano, Martins, Filipa, Santos, Inês, Rodrigues, Armanda, Silva, Fernanda, André, Saudade, Serpa, Jacinta

“…The biochemical demands associated with tumor proliferation prompt neoplastic cells to augment the import of nutrients to sustain their survival and fuel cell…”
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Canine neutrophils activate effector mechanisms in response to Leishmania infantum by Pereira, Maria, Valério-Bolas, Ana, Santos-Mateus, David, Alexandre-Pires, Graça, Santos, Marcos, Rodrigues, Armanda, Rocha, Hugo, Santos, Ana, Martins, Catarina, Tomas, Ana, Passero, Filipe, da Fonseca, Isabel Pereira, Santos-Gomes, Gabriela

“…•L. infantum binds to PMN via flagellum tip, promoting an efficient phagocytosis.•PMN microbicidal functions are properly activated, reducing initial parasite…”
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Intracellular and extracellular effector activity of mouse neutrophils in response to cutaneous and visceral Leishmania parasites by Valério-Bolas, Ana, Pereira, Maria, Alexandre-Pires, Graça, Santos-Mateus, David, Rodrigues, Armanda, Rafael-Fernandes, Mariana, Gabriel, Aurea, Passero, Felipe, Santos-Gomes, Gabriela

“…[Display omitted] •Neutrophils uptake Leishmania promastigotes and tolerate amastigote differentiation.•During early infection, parasites do not seem to signal…”
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Insights on Host–Parasite Immunomodulation Mediated by Extracellular Vesicles of Cutaneous ILeishmania shawi/I and ILeishmania guyanensis/I by Weber, Juliana Inês, Rodrigues, Armanda Viana, Valério-Bolas, Ana, Nunes, Telmo, Carvalheiro, Manuela, Antunes, Wilson, Alexandre-Pires, Graça, da Fonseca, Isabel Pereira, Santos-Gomes, Gabriela

“…Leishmaniasis is a parasitic disease caused by different species of Leishmania and transmitted through the bite of sand flies vector. Macrophages (MΦ), the…”
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