Search Results - "Rodrigues, Andria V."

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    Insight into the Mechanism of Phenylacetate Decarboxylase (PhdB), a Toluene‐Producing Glycyl Radical Enzyme by Rodrigues, Andria V., Tantillo, Dean J., Mukhopadhyay, Aindrila, Keasling, Jay D., Beller, Harry R.

    “…We recently reported the discovery of phenylacetate decarboxylase (PhdB), representing one of only ten glycyl‐radical‐enzyme reaction types known, and a…”
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    Journal Article
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    Drosophila melanogaster frataxin: protein crystal and predicted solution structure with identification of the iron‐binding regions by Rodrigues, Andria V., Batelu, Sharon, Hinton, Tiara V., Rotondo, John, Thompson, Lindsey, Brunzelle, Joseph S., Stemmler, Timothy L.

    “…Friedreich's ataxia (FRDA) is a hereditary cardiodegenerative and neurodegenerative disease that affects 1 in 50 000 Americans. FRDA arises from either a…”
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    Journal Article
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    Discovery of enzymes for toluene synthesis from anoxic microbial communities by Beller, Harry R., Rodrigues, Andria V., Zargar, Kamrun, Wu, Yu-Wei, Saini, Avneesh K., Saville, Renee M., Pereira, Jose H., Adams, Paul D., Tringe, Susannah G., Petzold, Christopher J., Keasling, Jay D.

    Published in Nature chemical biology (01-05-2018)
    “…Microbial toluene biosynthesis was reported in anoxic lake sediments more than three decades ago, but the enzyme catalyzing this biochemically challenging…”
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    Journal Article
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    Synthesis of Co(II)-NO(-) Complexes and Their Reactivity as a Source of Nitroxyl by Walter, Melody R, Dzul, Stephen P, Rodrigues, Andria V, Stemmler, Timothy L, Telser, Joshua, Conradie, Jeanet, Ghosh, Abhik, Harrop, Todd C

    Published in Journal of the American Chemical Society (28-09-2016)
    “…Metal-nitroxyl (M-HNO/M-NO(-)) coordination units are found in denitrification enzymes of the global nitrogen cycle, and free HNO exhibits pharmacological…”
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    Journal Article
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    Unique roles of iron and zinc binding to the yeast Fe-S cluster scaffold assembly protein "Isu1" by Lewis, Brianne E, Mason, Zachary, Rodrigues, Andria V, Nuth, Manunya, Dizin, Eric, Cowan, J. A, Stemmler, Timothy L

    Published in Metallomics (01-11-2019)
    “…Mitochondrial Fe-S cluster biosynthesis is accomplished within yeast utilizing the biophysical attributes of the "Isu1" scaffold assembly protein. As a member…”
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    Journal Article
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    Discovery of novel geranylgeranyl reductases and characterization of their substrate promiscuity by Meadows, Corey W, Mingardon, Florence, Garabedian, Brett M, Baidoo, Edward E K, Benites, Veronica T, Rodrigues, Andria V, Abourjeily, Raya, Chanal, Angelique, Lee, Taek Soon

    Published in Biotechnology for biofuels (28-12-2018)
    “…Geranylgeranyl reductase (GGR) is a flavin-containing redox enzyme that hydrogenates a variety of unactivated polyprenyl substrates, which are further…”
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    Journal Article
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    Iron chaperones for mitochondrial Fe–S cluster biosynthesis and ferritin iron storage by Subramanian, Poorna, Rodrigues, Andria V, Ghimire-Rijal, Sudipa, Stemmler, Timothy L

    Published in Current opinion in chemical biology (01-04-2011)
    “…Protein controlled iron homeostasis is essential for maintaining appropriate levels and availability of metal within cells. Recently, two iron chaperones have…”
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    Journal Article
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    Iron loading site on the Fe–S cluster assembly scaffold protein is distinct from the active site by Rodrigues, Andria V., Kandegedara, Ashoka, Rotondo, John A., Dancis, Andrew, Stemmler, Timothy L.

    Published in Biometals (01-06-2015)
    “…Iron–sulfur (Fe–S) cluster containing proteins are utilized in almost every biochemical pathway. The unique redox and coordination chemistry associated with…”
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    Journal Article
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    Backbone resonance assignments and secondary structure of the apo-Drosophila melanogaster frataxin homolog (Dfh) by Rawat, Swati, Kondapalli, Kalyan C., Rodrigues, Andria V., Stemmler, Timothy L.

    Published in Biomolecular NMR assignments (15-10-2019)
    “…Friedreich’s ataxia, the most prevalent hereditary ataxia, is caused by a patient’s inability to produce a viable form of the protein frataxin. Frataxin plays…”
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    Journal Article
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    Proton-Induced Reactivity of NO– from a {CoNO}8 Complex by Rhine, Melody A, Rodrigues, Andria V, Urbauer, Ramona J. Bieber, Urbauer, Jeffrey L, Stemmler, Timothy L, Harrop, Todd C

    Published in Journal of the American Chemical Society (10-09-2014)
    “…Research on the one-electron reduced analogue of NO, namely nitroxyl (HNO/NO–), has revealed distinguishing properties regarding its utility as a therapeutic…”
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    Journal Article
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    Characterization of initial iron binding location and the structure/iron binding site on S. cerevisiae isu and on D. melanogaster frataxin by Rodrigues, Andria V

    Published 01-01-2014
    “…Iron-induced free radical damage has been implicated in the pathology of diseases of iron overload such as Friedreich's Ataxia, a genetic disorder…”
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    Dissertation
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    Synthesis of CoII–NO– Complexes and Their Reactivity as a Source of Nitroxyl by Walter, Melody R, Dzul, Stephen P, Rodrigues, Andria V, Stemmler, Timothy L, Telser, Joshua, Conradie, Jeanet, Ghosh, Abhik, Harrop, Todd C

    Published in Journal of the American Chemical Society (28-09-2016)
    “…Metal-nitroxyl (M–HNO/M–NO–) coordination units are found in denitrification enzymes of the global nitrogen cycle, and free HNO exhibits pharmacological…”
    Get full text
    Journal Article