Search Results - "Rodrigues, A. D."

An experimentally supported model of the Bacillus subtilis global transcriptional regulatory network by Arrieta‐Ortiz, Mario L, Hafemeister, Christoph, Bate, Ashley Rose, Chu, Timothy, Greenfield, Alex, Shuster, Bentley, Barry, Samantha N, Gallitto, Matthew, Liu, Brian, Kacmarczyk, Thadeous, Santoriello, Francis, Chen, Jie, Rodrigues, Christopher DA, Sato, Tsutomu, Rudner, David Z, Driks, Adam, Bonneau, Richard, Eichenberger, Patrick

“…Organisms from all domains of life use gene regulation networks to control cell growth, identity, function, and responses to environmental challenges. Although…”
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Endogenous Probes for Drug Transporters: Balancing Vision With Reality by Rodrigues, AD, Taskar, KS, Kusuhara, H, Sugiyama, Y

“…Various endogenous probes have been identified for a number of hepatic and renal drug transporters and available clinical data indicate that they could be…”
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Ultrastructure of macromolecular assemblies contributing to bacterial spore resistance revealed by in situ cryo-electron tomography by Bauda, Elda, Gallet, Benoit, Moravcova, Jana, Effantin, Gregory, Chan, Helena, Novacek, Jiri, Jouneau, Pierre-Henri, Rodrigues, Christopher D. A., Schoehn, Guy, Moriscot, Christine, Morlot, Cecile

“…Bacterial spores owe their incredible resistance capacities to molecular structures that protect the cell content from external aggressions. Among the…”
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A two-step transport pathway allows the mother cell to nurture the developing spore in Bacillus subtilis by Ramírez-Guadiana, Fernando H, Meeske, Alexander J, Rodrigues, Christopher D A, Barajas-Ornelas, Rocío Del Carmen, Kruse, Andrew C, Rudner, David Z

“…One of the hallmarks of bacterial endospore formation is the accumulation of high concentrations of pyridine-2,6-dicarboxylic acid (dipicolinic acid or DPA) in…”
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Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast by Varma, MV, Kimoto, E, Scialis, R, Bi, Y, Lin, J, Eng, H, Kalgutkar, AS, El‐Kattan, AF, Rodrigues, AD, Tremaine, LM

“…Montelukast, a leukotriene receptor antagonist commonly prescribed for treatment of asthma, is primarily metabolized by cytochrome P450 (CYP)2C8, and has been…”
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Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters by Varma, MV, El‐Kattan, AF, Feng, B, Steyn, SJ, Maurer, TS, Scott, DO, Rodrigues, AD, Tremaine, LM

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The Min system and nucleoid occlusion are not required for identifying the division site in Bacillus subtilis but ensure its efficient utilization by Rodrigues, Christopher D A, Harry, Elizabeth J

“…Precise temporal and spatial control of cell division is essential for progeny survival. The current general view is that precise positioning of the division…”
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Co-digestion of Whey with Glycerin in an AnSBBR for Biomethane Production by Lovato, G, Ratusznei, S. M, Rodrigues, J. A. D, Zaiat, M

“…This study aimed to evaluate the co-digestion of cheese whey and glycerin in an anaerobic sequencing batch biofilm reactor (AnSBBR) with recirculation of the…”
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FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria by Landajuela, Ane, Braun, Martha, Rodrigues, Christopher D A, Martínez-Calvo, Alejandro, Doan, Thierry, Horenkamp, Florian, Andronicos, Anna, Shteyn, Vladimir, Williams, Nathan D, Lin, Chenxiang, Wingreen, Ned S, Rudner, David Z, Karatekin, Erdem

“…Little is known about mechanisms of membrane fission in bacteria despite their requirement for cytokinesis. The only known dedicated membrane fission machinery…”
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Organic Anion Transporting Polypeptide-Mediated Transport of, and Inhibition by, Asunaprevir, an Inhibitor of Hepatitis C Virus NS3 Protease by Eley, T, Han, Y-H, Huang, S-P, He, B, Li, W, Bedford, W, Stonier, M, Gardiner, D, Sims, K, Rodrigues, AD, Bertz, RJ

“…Asunaprevir (ASV), an investigational, highly protein‐bound inhibitor of hepatitis C virus NS3 protease, shows considerable hepatic compartmentalization in…”
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A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis by Luhur, Johana, Chan, Helena, Kachappilly, Benson, Mohamed, Ahmed, Morlot, Cécile, Awad, Milena, Lyras, Dena, Taib, Najwa, Gribaldo, Simonetta, Rudner, David Z, Rodrigues, Christopher D A

“…How organisms develop into specific shapes is a central question in biology. The maintenance of bacterial shape is connected to the assembly and remodelling of…”
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Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis by Ramírez-Guadiana, Fernando H, Rodrigues, Christopher D A, Marquis, Kathleen A, Campo, Nathalie, Barajas-Ornelas, Rocío Del Carmen, Brock, Kelly, Marks, Debora S, Kruse, Andrew C, Rudner, David Z

“…During the morphological process of sporulation in Bacillus subtilis two adjacent daughter cells (called the mother cell and forespore) follow different…”
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Anaerobic Biological Treatment of Vinasse for Environmental Compliance and Methane Production by Albanez, R, Chiaranda, B. C, Ferreira, R. G, França, A. L. P, Honório, C. D, Rodrigues, J. A. D, Ratusznei, S. M, Zaiat, M

“…The energy crisis resulted in increasing awareness that alternative sources of energy should be considered. During this time, Brazil implemented ethanol…”
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Hydroxyl Radical Overproduction in the Envelope: an Achilles' Heel in Peptidoglycan Synthesis by Giacomucci, Sean, Alvarez, Laura, Rodrigues, Christopher D A, Cava, Felipe, Paradis-Bleau, Catherine

“…While many mechanisms governing bacterial envelope homeostasis have been identified, others remain poorly understood. To decipher these processes, we…”
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Reimagining the Framework Supporting the Static Analysis of Transporter Drug Interaction Risk; Integrated Use of Biomarkers to Generate Pan‐Transporter Inhibition Signatures by Rodrigues, A.D.

“…Solute carrier (SLC) transporters present as the loci of important drug–drug interactions (DDIs). Therefore, sponsors generate in vitro half‐maximal inhibitory…”
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Effect of Feed Strategy on Methane Production and Performance of an AnSBBR Treating Effluent from Biodiesel Production by Lovato, Giovanna, Bezerra, Roberto A., Rodrigues, José A. D., Ratusznei, Suzana M., Zaiat, Marcelo

“…The aim of this work was to investigate the effect of different feeding times (2, 4 and 6 h) and applied volumetric organic loads (4.5, 6.0 and 7.5 gCOD L −1…”
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Nonpharmacological labor pain management methods and risk of cesarean birth: A retrospective cohort study by Rodrigues, Vanessa A. D. S., Abreu, Yahn R., Santos, Camila A. G., Gatti, Alan F., Murer, Gabriella M., Gontijo, Bárbara D. R., Alves, Juliana S., Cunha, Thayna M., Azevedo, Vivian Mara G. O., Mendonça, Tânia M. S., Paro, Helena B. M. S.

“…Background Nonpharmacological labor pain management methods (NPLPMM) are noninvasive, low‐cost practices that may play a role in reducing the rates of…”
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Biohydrogen Production in an AnSBBR Treating Glycerin-Based Wastewater: Effects of Organic Loading, Influent Concentration, and Cycle Time by Bravo, I. S. Moncayo, Lovato, G, Rodrigues, J. A. D, Ratusznei, S. M, Zaiat, M

“…This study evaluated the influence of the applied volumetric organic load on biohydrogen production in an anaerobic sequencing batch biofilm reactor (AnSBBR)…”
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Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro by Zhang, Yueping, Han, Yong-Hae, Putluru, Siva Prasad, Matta, Murali Krishna, Kole, Prashant, Mandlekar, Sandhya, Furlong, Michael T, Liu, Tongtong, Iyer, Ramaswamy A, Marathe, Punit, Yang, Zheng, Lai, Yurong, Rodrigues, A David

“…Although the metabolism and disposition of diclofenac (DF) has been studied extensively, information regarding the plasma levels of its acyl-β-d-glucuronide…”
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Effects of Organic Loading, Influent Concentration, and Feed Time on Biohydrogen Production in a Mechanically Stirred AnSBBR Treating Sucrose-Based Wastewater by Manssouri, M, Rodrigues, J. A. D, Ratusznei, S. M, Zaiat, M

“…An anaerobic sequencing batch biofilm reactor (AnSBBR—total volume 7.5 L; liquid volume 3.6 L; treated volume per cycle 1.5 L) treated sucrose-based wastewater…”
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