Search Results - "Rodrigue, Jacques"

Aromatic thioglycoside inhibitors against the virulence factor LecA from Pseudomonas aeruginosa by Rodrigue, Jacques, Ganne, Géraldine, Blanchard, Bertrand, Saucier, Catherine, Giguère, Denis, Shiao, Tze Chieh, Varrot, Annabelle, Imberty, Anne, Roy, René

“…Three small families of hydrolytically stable thioaryl glycosides were prepared as inhibitors of the LecA (PA-IL) virulence factor corresponding to the…”
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Combining Glycomimetic and Multivalent Strategies toward Designing Potent Bacterial Lectin Inhibitors by Chabre, Yoann M., Giguère, Denis, Blanchard, Bertrand, Rodrigue, Jacques, Rocheleau, Sylvain, Neault, Mathieu, Rauthu, Subhash, Papadopoulos, Alex, Arnold, Alexandre A., Imberty, Anne, Roy, René

“…As part of ongoing activities toward the design of potent and selective ligands against galactoside‐binding proteins from animal, bacterial, and plant lectins,…”
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Synthesis and evaluation of lysine derived sulfamides as histone deacetylase inhibitors by Manku, Sukhdev, Allan, Martin, Nguyen, Natalie, Ajamian, Alain, Rodrigue, Jacques, Therrien, Eric, Wang, James, Guo, Tim, Rahil, Jubrail, Petschner, Andrea J., Nicolescu, Alina, Lefebvre, Sylvain, Li, Zuomei, Fournel, Marielle, Besterman, Jeffrey M., Déziel, Robert, Wahhab, Amal

“…SAR investigation around compound 2a lead to 12h with equal HDAC1 and HDAC 6 inhibitory activity and enhanced metabolic stability and PK profile. We have…”
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