Search Results - "Rodrigo de Almeida"

Sporothrix schenckii and Sporotrichosis by DE LIMA BARROS, Monica Bastos, DE ALMEIDA PAES, Rodrigo, SCHUBACH, Armando Oliveira

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy by Barceló-Coblijn, Gwendolyn, Martin, Maria Laura, de Almeida, Rodrigo F. M, Noguera-Salvà, Maria Antònia, Marcilla-Etxenike, Amaia, Guardiola-Serrano, Francisca, Lüth, Anja, Kleuser, Burhard, Halver, John E, Escribá, Pablo V

“…The mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent antitumor compound, has not yet been fully elucidated. Here, we show that human cancer cells…”
Get full text

Interaction of the antifungal ketoconazole and its diphenylphosphine derivatives with lipid bilayers: Insights into their antifungal action by Bento-Oliveira, Andreia, Starosta, Radosław, de Almeida, Rodrigo F.M.

“…Ketoconazole (Ke) is an important antifungal drug, and two of its diphenylphosphinemethyl derivatives (KeP: Ph2PCH2-Ke and KeOP: Ph2P(O)CH2-Ke) have shown…”
Get full text

Sphingolipid hydroxylation in mammals, yeast and plants – An integrated view by Marquês, Joaquim Trigo, Marinho, H. Susana, de Almeida, Rodrigo F.M.

“…This review is focused on sphingolipid backbone hydroxylation, a small but widespread structural feature with profound impact on membrane biophysical…”
Get full text

C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations by de Matos, Ana Marta, Blázquez-Sánchez, Maria Teresa, Sousa, Carla, Oliveira, Maria Conceição, de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…The concept of Pan-Assay Interference Compounds (PAINS) is regarded as a threat to the recognition of the broad bioactivity of natural products. Based on the…”
Get full text

Anticandidal Cu(I) complexes with neocuproine and 1-(4-methoxyphenyl)piperazine based diphenylaminomethylphosphine: Is Cu-diimine moiety a pharmacophore? by Starosta, Radosław, de Almeida, Rodrigo F.M., Puchalska, Małgorzata, Suchodolski, Jakub, Derkacz, Daria, Krasowska, Anna

“…The studies on metal complexes as potential antifungals are of growing interest because they may be the answer to increasingly effective defense mechanisms…”
Get full text

Sphingolipid‐enriched domains in fungi by Santos, Filipa C., Marquês, Joaquim T., Bento‐Oliveira, Andreia, Almeida, Rodrigo F.M.

“…Plasma membrane carries out multiple physiological functions that require its dynamic and tightly regulated organization into specialized domains of different…”
Get full text

New anticandidal Cu(i) complexes with neocuproine and ketoconazole derived diphenyl(aminomethyl)phosphane: luminescence properties for detection in fungal cells by Starosta, Radosław, de Almeida, Rodrigo F M, Puchalska, Małgorzata, Białońska, Agata, Panek, Jarosław J, Jezierska, Aneta, Szmigiel, Ida, Suchodolski, Jakub, Krasowska, Anna

“…The search for new antifungals is very important because the large genetic variation of pathogenic organisms has resulted in the development of increasingly…”
Get more information

Gel Domains in the Plasma Membrane of Saccharomyces cerevisiae: HIGHLY ORDERED, ERGOSTEROL-FREE, AND SPHINGOLIPID-ENRICHED LIPID RAFTS by Aresta-Branco, Francisco, Cordeiro, André M, Marinho, H. Susana, Cyrne, Luísa, Antunes, Fernando, de Almeida, Rodrigo F.M

“…The plasma membrane of Saccharomyces cerevisiae was studied using the probes trans-parinaric acid and diphenylhexatriene. Diphenylhexatriene anisotropy is a…”
Get full text

Cholesterol-rich Fluid Membranes Solubilize Ceramide Domains: IMPLICATIONS FOR THE STRUCTURE AND DYNAMICS OF MAMMALIAN INTRACELLULAR AND PLASMA MEMBRANES by Castro, Bruno M, Silva, Liana C, Fedorov, Alexander, de Almeida, Rodrigo F.M, Prieto, Manuel

“…A uniquely sensitive method for ceramide domain detection allowed us to study in detail cholesterol-ceramide interactions in lipid bilayers with low…”
Get full text

Sphingomyelin/Phosphatidylcholine/Cholesterol Phase Diagram: Boundaries and Composition of Lipid Rafts by de Almeida, Rodrigo F.M., Fedorov, Aleksandre, Prieto, Manuel

“…The ternary system palmitoylsphingomyelin (PSM)/palmitoyloleoylphosphatidylcholine (POPC)/cholesterol is used to model lipid rafts. The phase behavior of the…”
Get full text

Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity by Demoro, Bruno, Bento-Oliveira, Andreia, Marques, Fernanda, Costa Pessoa, João, Otero, Lucía, Gambino, Dinorah, F M de Almeida, Rodrigo, Tomaz, Ana Isabel

“…The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite…”
Get full text

Evaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives by Alguacil, Andres, Scalambra, Franco, Romerosa, Antonio, Bento-Oliveira, Andreia, Marques, Fernanda, Maximiano, Ines, de Almeida, Rodrigo F. M., Tomaz, Ana Isabel, Valente, Andreia

“…Piano-stool-{CpRu} complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA), N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA), and…”
Get full text

A route to understanding yeast cellular envelope – plasma membrane lipids interplaying in cell wall integrity by Almeida, Rodrigo F. M.

“…Sphingolipids and sterols are major components of the plasma membrane in eukaryotic cells. A recent study provides new insight into the intricate but…”
Get full text

Biophysical Analysis of Lipid Domains in Mammalian and Yeast Membranes by Fluorescence Spectroscopy by Sousa, Carla, Santos, Filipa C, Bento-Oliveira, Andreia, Mestre, Beatriz, Silva, Liana C, de Almeida, Rodrigo F M

“…The use of steady-state and time-resolved fluorescence spectroscopy to study sterol and sphingolipid-enriched lipid domains as diverse as the ones found in…”
Get more information

Differential targeting of membrane lipid domains by caffeic acid and its ester derivatives by Filipe, Hugo A.L., Sousa, Carla, Marquês, Joaquim T., Vila-Viçosa, Diogo, de Granada-Flor, António, Viana, Ana S., Santos, M. Soledade C.S., Machuqueiro, Miguel, de Almeida, Rodrigo F.M.

“…Phenolic acids have been associated to a wide range of important health benefits underlain by a common molecular mechanism of action. Considering that…”
Get full text

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes by Dias, Catarina, Pais, João P., Nunes, Rafael, Blázquez-Sánchez, Maria-Teresa, Marquês, Joaquim T., Almeida, Andreia F., Serra, Patrícia, Xavier, Nuno M., Vila-Viçosa, Diogo, Machuqueiro, Miguel, Viana, Ana S., Martins, Alice, Santos, Maria S., Pelerito, Ana, Dias, Ricardo, Tenreiro, Rogério, Oliveira, Maria C., Contino, Marialessandra, Colabufo, Nicola A., de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…Anthrax is an infectious disease caused by Bacillus anthracis , a bioterrorism agent that develops resistance to clinically used antibiotics. Therefore,…”
Get full text

Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis by Salviano-Silva, Amanda, Lobo-Alves, Sara Cristina, Almeida, Rodrigo Coutinho de, Malheiros, Danielle, Petzl-Erler, Maria Luiza

“…A significant proportion of mammalian genomes corresponds to genes that transcribe long non-coding RNAs (lncRNAs). Throughout the last decade, the number of…”
Get full text

Formation of Ceramide/Sphingomyelin Gel Domains in the Presence of an Unsaturated Phospholipid: A Quantitative Multiprobe Approach by Castro, Bruno M., de Almeida, Rodrigo F.M., Silva, Liana C., Fedorov, Alexander, Prieto, Manuel

“…To better understand how ceramide modulates the biophysical properties of the membrane, the interactions between palmitoyl-ceramide (PCer) and…”
Get full text

New diphenylphosphane derivatives of ketoconazole are promising antifungal agents by de Almeida, Rodrigo F. M., Santos, Filipa C., Marycz, Krzysztof, Alicka, Michalina, Krasowska, Anna, Suchodolski, Jakub, Panek, Jarosław J., Jezierska, Aneta, Starosta, Radosław

“…Four new derivatives of ketoconazole ( Ke ) were synthesized: diphenylphosphane ( KeP ), and phosphane chalcogenides: oxide ( KeOP ), sulphide ( KeSP ) and…”
Get full text