Search Results - "Rodrigo Secolin"

A review of ancestrality and admixture in Latin America and the caribbean focusing on native American and African descendant populations by De Oliveira, Thais C, Secolin, Rodrigo, Lopes-Cendes, Iscia

“…Genomics can reveal essential features about the demographic evolution of a population that may not be apparent from historical elements. In recent years,…”
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Genetic variability in COVID-19-related genes in the Brazilian population by Secolin, Rodrigo, de Araujo, Tânia K., Gonsales, Marina C., Rocha, Cristiane S., Naslavsky, Michel, Marco, Luiz De, Bicalho, Maria A. C., Vazquez, Vinicius L., Zatz, Mayana, Silva, Wilson A., Lopes-Cendes, Iscia

“…SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptor and transmembrane serine protease (TMPRSS2) to infect human lung cells. Previous…”
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MicroRNA hsa-miR-134 is a circulating biomarker for mesial temporal lobe epilepsy by Avansini, Simoni H, de Sousa Lima, Beatriz Pereira, Secolin, Rodrigo, Santos, Marilza L, Coan, Ana Carolina, Vieira, André S, Torres, Fábio R, Carvalho, Benilton S, Alvim, Marina K M, Morita, Márcia E, Yasuda, Clarissa L, Pimentel-Silva, Luciana R, Dogini, Danyella B, Rogerio, Fabio, Cendes, Fernando, Lopes-Cendes, Iscia

“…Epilepsy is misdiagnosed in up to 25% of patients, leading to serious and long-lasting consequences. Recently, circulating microRNAs have emerged as potential…”
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The Brazilian Initiative on Precision Medicine (BIPMed): fostering genomic data-sharing of underrepresented populations by Rocha, Cristiane S., Secolin, Rodrigo, Rodrigues, Maíra R., Carvalho, Benilton S., Lopes-Cendes, Iscia

“…The development of precision medicine strategies requires prior knowledge of the genetic background of the target population. However, despite the availability…”
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Dysregulation of NEUROG2 plays a key role in focal cortical dysplasia by Avansini, Simoni H., Torres, Fábio R., Vieira, André S., Dogini, Danyella B., Rogerio, Fabio, Coan, Ana C., Morita, Marcia E., Guerreiro, Marilisa M., Yasuda, Clarissa L., Secolin, Rodrigo, Carvalho, Benilton S., Borges, Murilo G., Almeida, Vanessa S., Araújo, Patrícia A. O. R., Queiroz, Luciano, Cendes, Fernando, Lopes‐Cendes, Iscia

“…Objective Focal cortical dysplasias (FCDs) are an important cause of drug‐resistant epilepsy. In this work, we aimed to investigate whether abnormal gene…”
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A Prediction Algorithm for Drug Response in Patients with Mesial Temporal Lobe Epilepsy Based on Clinical and Genetic Information by Silva-Alves, Mariana S, Secolin, Rodrigo, Carvalho, Benilton S, Yasuda, Clarissa L, Bilevicius, Elizabeth, Alvim, Marina K M, Santos, Renato O, Maurer-Morelli, Claudia V, Cendes, Fernando, Lopes-Cendes, Iscia

“…Mesial temporal lobe epilepsy is the most common form of adult epilepsy in surgical series. Currently, the only characteristic used to predict poor response to…”
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Neurocysticercotic Calcifications and Hippocampal Sclerosis: A Case-Control Study by de Oliveira Taveira, Mateus, Morita, Marcia Elisabete, Yasuda, Clarissa Lin, Coan, Ana Carolina, Secolin, Rodrigo, Luiz Cunha da Costa, Alberto, Cendes, Fernando

“…The exact role of calcified neurocysticercotic lesions (CNLs) in epilepsy is yet unknown and controversial. Although the relationship between CNLs, epilepsy…”
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Exploring a Region on Chromosome 8p23.1 Displaying Positive Selection Signals in Brazilian Admixed Populations: Additional Insights Into Predisposition to Obesity and Related Disorders by Secolin, Rodrigo, Gonsales, Marina C, Rocha, Cristiane S, Naslavsky, Michel, De Marco, Luiz, Bicalho, Maria A C, Vazquez, Vinicius L, Zatz, Mayana, Silva, Wilson A, Lopes-Cendes, Iscia

“…We recently reported a deviation of local ancestry on the chromosome (ch) 8p23.1, which led to positive selection signals in a Brazilian population sample. The…”
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Gene Variants Associated With Venous Thrombosis: A Replication Study in a Brazilian Multicentre Study by Romano, Anna Virgínia Calazans, Barnabé, Aline, Gadelha, Telma Barbosa, Guerra, João Carlos de Campos, Secolin, Rodrigo, Orsi, Fernanda Loureiro de Andrade, Campanate, Gizele de Castro Sousa, Wolosker, Nelson, Annichino-Bizzacchi, Joyce Maria

“…Single nucleotide polymorphisms (SNP) associated with Venous Thromboembolism (VTE) risk have been identified in European and American populations. Replicate…”
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Increased runs of homozygosity in the autosomal genome of Brazilian individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies investigated by chromosomal microarray analysis by Correia-Costa, Gabriela Roldão, Sgardioli, Ilária Cristina, Santos, Ana Paula Dos, Araujo, Tânia Kawasaki de, Secolin, Rodrigo, Lopes-Cendes, Iscia, Gil-da-Silva-Lopes, Vera Lúcia, Vieira, Társis Paiva

“…Runs of homozygosity (ROH) in the human genome may be clinically relevant. The aim of this study was to report the frequency of increased ROH of the autosomal…”
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Inheritance pattern of molar-incisor hypomineralization by Jeremias, Fabiano, Bussaneli, Diego Girotto, Restrepo, Manuel, Pierri, Ricardo Augusto Gonçalves, Souza, Juliana Feltrin de, Fragelli, Camila Maria Bullio, Secolin, Rodrigo, Maurer-Morelli, Claudia Vianna, Cordeiro, Rita de Cassia Loiola, Scarel-Caminaga, Raquel Mantuaneli, Santos-Pinto, Lourdes

“…The aim of this study was to investigate the segregation patterns of molar incisor hypomineralization (MIH) in families, given the evidence that its etiology…”
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A multicentric association study between 39 genes and nonsyndromic cleft lip and palate in a Brazilian population by Araujo, Tânia Kawasaki de, Secolin, Rodrigo, Félix, Têmis Maria, Souza, Liliane Todeschini de, Fontes, Marshall Ítalo Barros, Monlleó, Isabella Lopes, Souza, Josiane de, Fett-Conte, Agnes Cristina, Ribeiro, Erlane Marques, Xavier, Ana Carolina, Rezende, Adriana Augusto de, Simioni, Milena, Ribeiro-dos-Santos, Ândrea Kely Campos, Santos, Sidney Emanuel Batista dos, Gil-da-Silva-Lopes, Vera Lúcia

“…Abstract Purpose The aim of this study was to use the TaqMan OpenArray system to evaluate associations between 39 genes and the etiology of nonsyndromic cleft…”
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Association Analysis of Candidate Variants in Admixed Brazilian Patients With Genetic Generalized Epilepsies by Kaibara, Felipe S., de Araujo, Tânia K., Araujo, Patricia A. O. R. A., Alvim, Marina K. M., Yasuda, Clarissa L., Cendes, Fernando, Lopes-Cendes, Iscia, Secolin, Rodrigo

“…Genetic generalized epilepsies (GGEs) include well-established epilepsy syndromes with generalized onset seizures: childhood absence epilepsy, juvenile…”
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Demographic history differences between Hispanics and Brazilians imprint haplotype features by da Cruz, Pedro Rodrigues Sousa, Ananina, Galina, Secolin, Rodrigo, Gil-da-Silva-Lopes, Vera Lúcia, Lima, Carmen Silvia Passos, de França, Paulo Henrique Condeixa, Donatti, Amanda, Lourenço, Gustavo Jacob, de Araujo, Tânia Kawasaki, Simioni, Milena, Lopes-Cendes, Iscia, Costa, Fernando Ferreira, de Melo, Mônica Barbosa

“…Admixture is known to greatly impact the genetic landscape of a population and, while genetic variation underlying human phenotypes has been shown to differ…”
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Multidimensional Approach Assessing the Role of Interleukin 1 Beta in Mesial Temporal Lobe Epilepsy by Santos, Renato O., Secolin, Rodrigo, Barbalho, Patrícia G., Silva-Alves, Mariana S., Alvim, Marina K. M., Yasuda, Clarissa L., Rogerio, Fábio, Velasco, Tonicarlo R., Sakamoto, Americo C., Teixeira, Antonio L., Cendes, Fernando, Maurer-Morelli, Claudia V., Lopes-Cendes, Iscia

“…We aimed to investigate the role of interleukin-1 beta (IL-1β) in the mechanisms underlying mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE+HS)…”
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Inducible Nitric Oxide Synthase Polymorphisms and Nitric Oxide Levels in Individuals with Chronic Periodontitis by Scarel-Caminaga, Raquel M, Cera, Flávia F, Pigossi, Suzane C, Finoti, Livia S, Kim, Yeon J, Viana, Aline C, Secolin, Rodrigo, Montenegro, Marcelo F, Tanus-Santos, José E, Orrico, Silvana R P, Cirelli, Joni A

“…This study aimed to investigate whether the -1026(A>C)(rs2779249) and +2087(A>G)(2297518) polymorphisms in the gene were associated with chronic periodontitis…”
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p.Q192R SNP of PON1 seems not to be Associated with Carotid Atherosclerosis Risk Factors in an Asymptomatic and Normolipidemic Brazilian Population Sample by Scherrer, Daniel Zanetti, Zago, Vanessa Helena de Souza, Vieira, Isabela Calanca, Parra, Eliane Soler, Panzoldo, Natália Baratella, Alexandre, Fernanda, Secolin, Rodrigo, Baracat, Jamal, Quintão, Eder Carlos Rocha, Faria, Eliana Cotta de

“…Evidences suggest that paraoxonase 1 (PON1) confers important antioxidant and anti-inflammatory properties when associated with high-density lipoprotein (HDL)…”
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Assessing treatment response to prophylactic lithium use in patients with bipolar disorder by Silva, Luiz Fernando de Almeida Lima e, Loureiro, Júlia Cunha, Franco, Stephany Caroline Raposo, Santos, Marilza de Lima, Secolin, Rodrigo, Lopes-Cendes, Iscia, Dantas, Clarissa de Rosalmeida, Banzato, Claudio E. M.

“…ABSTRACT Objetive To identify potential clinical and epidemiological predictors of long-term response to lithium treatment. Methods A total of 40 adult…”
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Lack of association between the prothrombin rs1799963 polymorphism and juvenile myoclonic epilepsy by Born, João Paulo Lopes, Santos, Bruna Priscila dos, Secolin, Rodrigo, Gameleira, Fernando Tenório, Andrade, Tiago Gomes de, Machado, Luciana Cláudia Herculano, Gitaí, Lívia Leite Góes, Gitaí, Daniel Leite Góes

“…Juvenile myoclonic epilepsy (JME) accounts for 26% of generalized idiopathic epileptic syndromes. The highest levels of thrombin activity are closely involved…”
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Analysis of energetically biased transcripts of viruses and transposable elements by Secolin, Rodrigo, Pascoal, Vinícius D'Ávila Bitencourt, Lopes-Cendes, Iscia, Pereira, Tiago Campos

“…RNA interference (RNAi) is a natural endogenous process by which double-stranded RNA molecules trigger potent and specific gene silencing in eukaryotic cells…”
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