Search Results - "Rodrigo Pacheco"
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Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases
Published in Journal of neuroimmunology (15-09-2014)“…Abstract Neuroinflammation constitutes a fundamental process involved in the progression of several neurodegenerative disorders, such as Parkinson's disease,…”
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Cross-talk between T-cells and gut-microbiota in neurodegenerative disorders
Published in Neural regeneration research (01-12-2019)“…According to the important role that gut-microbiota plays in maintaining homeostasis, alterations in the composition of gut-microbiota (dysbiosis) have…”
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T-cell based immunotherapies for Parkinson’s disease
Published in Exploration of neuroprotective therapy (03-10-2021)“…Current evidence indicates that neurodegeneration of dopaminergic neurons of the substantia nigra associated to Parkinson’s disease is a consequence of a…”
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Magnetic nanoparticles for drug delivery
Published in Nano today (01-06-2007)“…Controlled release of drugs from nanostructured functional materials, especially nanoparticles (NPs), is attracting increasing attention because of the…”
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T-Cell-Driven Inflammation as a Mediator of the Gut-Brain Axis Involved in Parkinson's Disease
Published in Frontiers in immunology (15-02-2019)“…Parkinson's disease (PD) is a neurodegenerative disorder affecting mainly the dopaminergic neurons of the nigrostriatal pathway, a neuronal circuit involved in…”
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The Cross-Talk Between the Dopaminergic and the Immune System Involved in Schizophrenia
Published in Frontiers in pharmacology (31-03-2020)“…Dopamine is one of the neurotransmitters whose transmission is altered in a number of neural pathways in the brain of schizophrenic patients. Current evidence…”
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The relevance of Brownian relaxation as power absorption mechanism in Magnetic Hyperthermia
Published in Scientific reports (08-03-2019)“…The Linear Response Theory (LRT) is a widely accepted framework to analyze the power absorption of magnetic nanoparticles for magnetic fluid hyperthermia. Its…”
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Meningeal T-cells in the cross-talk between memory consolidation and sleep
Published in Neural regeneration research (01-12-2023)Get full text
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Magnetite Biomineralization in Magnetospirillum gryphiswaldense: Time-Resolved Magnetic and Structural Studies
Published in ACS nano (23-04-2013)“…Magnetotactic bacteria biosynthesize magnetite nanoparticles of high structural and chemical purity that allow them to orientate in the geomagnetic field. In…”
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The hormonal physiology of immune components in breast milk and their impact on the infant immune response
Published in Molecular and cellular endocrinology (15-07-2023)“…During pregnancy, the maternal body undergoes a considerable transformation regarding the anatomy, metabolism, and immune profile that, after delivery, allows…”
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Targeting short-chain fatty acids receptors signalling for neurological disorders treatment
Published in Exploration of neuroprotective therapy (19-03-2024)“…Short-chain fatty acids (SCFAs) play a key role regulating immune and metabolic homeostasis. Consequently, dysregulation in SCFA levels is involved in the…”
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Nanostructured Mixed Matrix Membranes from Supramolecular Assembly of Block Copolymer Nanoparticles and Iron Oxide Nanoparticles
Published in Macromolecules (25-10-2016)“…Mixed matrix membranes having combined properties of both polymeric and inorganic materials have become the principal focus on separation technology. This work…”
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Influence of Magnetic Nanoparticles on PISA Preparation of Poly(Methacrylic Acid)‐b‐Poly(Methylmethacrylate) Nano‐Objects
Published in Macromolecular rapid communications. (01-01-2019)“…This article presents the synthesis of poly(methacrylic acid)‐b‐poly(methyl methacrylate) diblock copolymer via polymerization‐induced self‐assembly in the…”
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High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation
Published in The Journal of biological chemistry (20-07-2018)“…The role of albumin reabsorption in proximal tubule (PT) cells has emerged as an important factor in the genesis of albuminuria observed in the early stages of…”
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Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation
Published in Journal of neuroinflammation (06-12-2019)“…Neuroinflammation constitutes a pathogenic process leading to neurodegeneration in several disorders, including Alzheimer's disease, Parkinson's disease (PD)…”
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Assessing Methods for Blood Cell Cytotoxic Responses to Inorganic Nanoparticles and Nanoparticle Aggregates
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2008)“…Inorganic nanoparticles (NPs) show great potential for medicinal therapy. However, biocompatibility studies are essential to determine if they are safe. Here,…”
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Nanoparticle penetration and transport in living pumpkin plants: in situ subcellular identification
Published in BMC plant biology (23-04-2009)“…In recent years, the application of nanotechnology in several fields of bioscience and biomedicine has been studied. The use of nanoparticles for the targeted…”
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Calcium salts of fatty acids with varying fatty acid profiles in diets of feedlot-finished Bos indicus bulls: impacts on intake, digestibility, performance, and carcass and meat characteristics
Published in Journal of animal science (01-12-2020)“…Abstract We hypothesized that the inclusion of calcium salts of fatty acid (CSFA) into the diets and the fatty acid (FA) profile of the supplements would…”
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Protein-Templated Biomimetic Silica Nanoparticles
Published in Langmuir (31-03-2015)“…Biomimetic silica particles can be synthesized as a nanosized material within minutes in a process mimicked from living organisms such as diatoms and sponges…”
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Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells
Published in Frontiers in cellular neuroscience (10-07-2018)“…A number of studies have shown pharmacologic evidence indicating that stimulation of type I dopamine receptor (DR), favors T-helper-17 (Th17)-mediated immunity…”
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