Search Results - "Rodrigo Moreira da Silva"

Preclinical Monitoring of Drug Association in Experimental Chemotherapy of Chagas' Disease by a New HPLC-UV Method by Moreira da Silva, Rodrigo, Oliveira, Líliam Teixeira, Silva Barcellos, Neila Márcia, de Souza, Jacqueline, de Lana, Marta

“…A combination of drugs in experimental chemotherapy of Chagas' disease may increase the effectiveness of treatment. To evaluate the possible mechanisms that…”
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The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils by Toller-Kawahisa, Juliana Escher, Hiroki, Carlos Hiroji, Silva, Camila Meirelles de Souza, Nascimento, Daniele Carvalho, Públio, Gabriel Azevedo, Martins, Timna Varela, Damasceno, Luis Eduardo Alves, Veras, Flávio Protásio, Viacava, Paula Ramos, Sukesada, Fábio Yuji, Day, Emily Anne, Zotta, Alessia, Ryan, Tristram Alexander Jasper, Moreira da Silva, Rodrigo, Cunha, Thiago Mattar, Lopes, Norberto Peporine, Cunha, Fernando de Queiroz, O’Neill, Luke Anthony John, Alves-Filho, José Carlos

“…Neutrophils rely predominantly on glycolytic metabolism for their biological functions, including reactive oxygen species (ROS) production. Although pyruvate…”
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Determination of topiramate by capillary electrophoresis with capacitively‐coupled contactless conductivity detection: A powerful tool for therapeutic monitoring in epileptic patients by Ishikawa, Aline Akemi, da Silva, Rodrigo Moreira, Santos, Mauro Sérgio Ferreira, da Costa, Eric Tavares, Sakamoto, Americo Ceiki, Carrilho, Emanuel, de Gaitani, Cristiane Masetto, Garcia, Carlos D.

“…Topiramate (TPM) is the main antiepileptic drug used for the control of partial and generalized seizures in both adults and children. In association with…”
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Prediction of seriniquinone-drug interactions by in vitro inhibition of human cytochrome P450 enzymes by Moreira da Silva, Rodrigo, Carrão, Daniel Blascke, Habenschus, Maísa Daniela, Jimenez, Paula Christine, Lopes, Norberto Peporine, Fenical, William, Costa-Lotufo, Letícia Vera, de Oliveira, Anderson Rodrigo Moraes

“…Seriniquinone is a secondary metabolite isolated from a rare marine bacterium of the genus Serinicoccus. This natural quinone is highlighted for its selective…”
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IN VITRO METABOLISM OF COPALIC AND KAURENOIC ACIDS IN RAT AND HUMAN LIVER MICROSOMES by Mauro, Mariana, Silva, Rodrigo, Campos, Michel, Bauermeister, Anelize, Lopes, Norberto, Moraes, Natalia

“…Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to…”
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In vitro-in vivo correlation of the chiral pesticide prothioconazole after interaction with human CYP450 enzymes by Perovani, Icaro Salgado, Santos Barbetta, Maike Felipe, Moreira da Silva, Rodrigo, Lopes, Norberto Peporine, Moraes de Oliveira, Anderson Rodrigo

“…Growing human demand for food has culminated in increased use of pesticides worldwide. Prothioconazole (PTC), a profungicide, is bioactivated by metabolic PTC…”
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Chemometric optimization of salting-out assisted liquid–liquid extraction (SALLE) combined with LC-MS/MS for the analysis of carvedilol enantiomers in human plasma: Application to clinical pharmacokinetics by Pavan, Marcella, Yamamoto, Priscila, Moreira da Silva, Rodrigo, Salgado Junior, Wilson, dos Santos, José, Kemp, Rafael, Sankarankutty, Ajith, de Moraes, Natália, de Gaitani, Cristiane

“…•First optimized SALLE for analysis of carvedilol in plasma by LC-MS/MS.•Enantioselective method suitable for clinical pharmacokinetic applications.•Fast,…”
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Characterization of the fragmentation mechanisms in electrospray ionization tandem mass spectrometry of chloroquinoline derivatives with larvicidal activity against Aedes aegypti by Silva, Rodrigo Moreira, Barbieri, Jéssica Guastalli, Murie, Valter Eduardo, Silvério, Maíra Rosato Silveira, Soldi, Rafael Augusto, Albernaz, Lorena Carneiro, Espindola, Laila Salmen, Vieira, Paulo Cézar, Clososki, Giuliano Cesar, Vessecchi, Ricardo, Lopes, Norberto Peporine

“…Rationale 4,7‐Dichloroquinoline (DCQ) represents a group of synthetic molecules inspired by natural products with important roles in biological and biomedical…”
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Enantioselective inhibition of human CYP2C19 by the chiral pesticide ethofumesate: Prediction of pesticide-drug interactions in humans by Perovani, Icaro Salgado, Mariano Bucci, Jade Lorena, Carrão, Daniel Blascke, Santos Barbetta, Maike Felipe, Moreira da Silva, Rodrigo, Lopes, Norberto Peporine, Moraes de Oliveira, Anderson Rodrigo

“…Ethofumesate is a chiral herbicide that may display enantioselective behavior in humans. For this reason, the enantioselective potential of ethofumesate and…”
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Effect of Roux‐En‐Y Gastric Bypass in the Pharmacokinetics of (R)‐Carvedilol and (S)‐Carvedilol by Yamamoto, Priscila Akemi, Cristofoletti, Rodrigo, Vozmediano, Valvanera, Gaitani, Cristiane Masetto, da Silva, Rodrigo Moreira, Kemp, Rafael, Sankarankutty, Ajith Kumar, Salgado Junior, Wilson, Santos, Jose Sebastião dos, Moraes, Natalia Valadares

“…Roux‐en‐Y gastric bypass is one of the most common surgical treatments for obesity due to the effective long‐term weight loss and remission of associated…”
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Pharmacokinetics and Tissue Distribution of Benznidazole after Oral Administration in Mice by Perin, Luísa, Moreira da Silva, Rodrigo, Fonseca, Kátia da Silva, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, Reis, Levi Eduardo Soares, Molina, Israel, Correa-Oliveira, Rodrigo, Vieira, Paula Melo de Abreu, Carneiro, Cláudia Martins

“…Specific chemotherapy using benznidazole (BNZ) for Chagas disease during the chronic stage is controversial due to its limited efficacy and toxic effects…”
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Regionalização e desenvolvimento humano: uma proposta de tipologia de Regiões de Saúde no Brasil by Duarte, Cristina Maria Rabelais, Pedroso, Marcel de Moraes, Bellido, Jaime Gregório, Moreira, Rodrigo da Silva, Viacava, Francisco

“…O objetivo do trabalho foi apresentar uma proposta de diferenciação das Regiões de Saúde no Brasil, baseada no desenvolvimento humano, contribuindo para a…”
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In vitro enantioselective inhibition of the main human CYP450 enzymes involved in drug metabolism by the chiral pesticide tebuconazole by Habenschus, Maísa Daniela, Carrão, Daniel Blascke, de Albuquerque, Nayara Cristina Perez, Perovani, Icaro Salgado, Moreira da Silva, Rodrigo, Nardini, Viviani, Lopes, Norberto Peporine, Dias, Luís Gustavo, Moraes de Oliveira, Anderson Rodrigo

“…•Rac-Tebuconazole and its isolated enantiomers inhibited CYP3A4/5, 2C9, 2C19 and 2D6.•Inhibition was enantioselective for CYP2C9, CYP2C19 and…”
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Risk assessment of the chiral pesticide fenamiphos in a human model: Cytochrome P450 phenotyping and inhibition studies by de Albuquerque, Nayara Cristina Perez, Carrão, Daniel Blascke, Habenschus, Maísa Daniela, Fonseca, Franciele Saraiva, Moreira da Silva, Rodrigo, Lopes, Norberto Peporine, Rocha, Bruno Alves, Barbosa Júnior, Fernando, de Oliveira, Anderson Rodrigo Moraes

“…Fenamiphos (FS) is a chiral organophosphate pesticide that is used to control nematodes in several crops. Enantioselective differences may be observed in FS…”
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Topical gel containing phenolic-rich extract from Ipomoea pes-capre leaf (Convolvulaceae) has anti-inflammatory, wound healing, and antiophidic properties by Xavier-Santos, Jacinthia Beatriz, Passos, Júlia Gabriela Ramos, Gomes, Jacyra Antunes Santos, Cruz, Joelly Vilaine Cavalcante, Alves, Jovelina Samara Ferreira, Garcia, Vinícius Barreto, da Silva, Rodrigo Moreira, Lopes, Norberto Peporine, Araujo-Junior, Raimundo Fernandes, Zucolotto, Silvana Maria, Silva-Junior, Arnóbio Antônio, Félix-Silva, Juliana, Fernandes-Pedrosa, Matheus Freitas

“…The growing use of phytotherapy in clinical practice arouses interest in studies using medicinal plants as active ingredients for new medicines. Ipomoea…”
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Evaluation of the Intestinal Absorption Mechanism of Casearin X in Caco‑2 Cells with Modified Carboxylesterase Activity by Moreira da Silva, Rodrigo, Verjee, Sheela, de Gaitani, Cristiane Masetto, Moraes de Oliveira, Anderson Rodrigo, Pires Bueno, Paula Carolina, Cavalheiro, Alberto José, Peporine Lopes, Norberto, Butterweck, Veronika

“…The clerodane diterpene casearin X (1), isolated from the leaves of Casearia sylvestris, is a potential new drug candidate due to its potent in vitro cytotoxic…”
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A possible solution to model nonlinearity in elimination and distributional clearances with α2‐adrenergic receptor agonists: Example of the intravenous detomidine and methadone combination in sedated horses by Gozalo‐Marcilla, Miguel, Moreira da Silva, Rodrigo, Pacca Loureiro Luna, Stelio, Rodrigues de Oliveira, Alice, Werneck Fonseca, Mariana, Peporine Lopes, Norberto, Taylor, Polly M., Pelligand, Ludovic

“…The alpha(α)2‐agonist detomidine is used for equine sedation with opioids such as methadone. We retrieved the data from two randomized, crossover studies where…”
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In Vivo Antidepressant Effect of Passiflora edulis f. flavicarpa into Cationic Nanoparticles: Improving Bioactivity and Safety by Alves, Jovelina Samara Ferreira, Silva, Alaine Maria Dos Santos, da Silva, Rodrigo Moreira, Tiago, Pamella Rebeca Fernandes, de Carvalho, Thais Gomes, de Araújo Júnior, Raimundo Fernandes, de Azevedo, Eduardo Pereira, Lopes, Norberto Peporine, Ferreira, Leandro De Santis, Gavioli, Elaine Cristina, da Silva-Júnior, Arnóbio Antônio, Zucolotto, Silvana Maria

“…A variety of neuroactive flavonoids can be found in the species of the genus; however, their difficulty in crossing the blood-brain barrier limits their in…”
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Estimates of mammography coverage according to health surveys in Brazil by Viacava, Francisco, Souza-Junior, Paulo Roberto Borges de, Moreira, Rodrigo da Silva

“…Population surveys constitute an essential tool to monitor mammography coverage and factors associated with its performance. Estimates tend to be overestimated…”
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Uma analise da utilizacao de servicos de saude por sistema de financiamento: Brasil 1998-2008 by Porto, Silvia Marta, Dominguez Ugá, Maria Alicia, da Silva Moreira, Rodrigo

“…Este artigo analisa, a partir de microdados de 1998, 2003 e 2008 da PNAD/IBGE, a utilização de serviços de saúde sob a perspectiva de seu financiamento Entre…”
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