Search Results - "Rodrigo, Vanessa"

Asymmetric Synthesis of New β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives by Fustero, Santos, Sánchez-Roselló, María, Rodrigo, Vanessa, del Pozo, Carlos, Sanz-Cervera, Juan F, Simón, Antonio

“…The synthesis of new β,β-difluorinated cyclic quaternary α-amino acid derivatives 1 in which a ring-closing metathesis reaction (RCM) constitutes the key step…”
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New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation by Fustero, Santos, Rodrigo, Vanessa, Sánchez-Roselló, María, del Pozo, Carlos, Timoneda, Joaquín, Frizler, Maxim, Sisay, Mihiret T., Bajorath, Jürgen, Calle, Luis P., Cañada, F. Javier, Jiménez-Barbero, Jesús, Gütschow, Michael

“…Fluor‐in or out? Based on β,β‐difluorinated cycloaliphatic amino acids, a library of new dipeptide nitriles was evaluated as human cathepsin inhibitors. The…”
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Solution-, Solid-Phase, and Fluorous Synthesis of β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives: A Comparative Study by Fustero, Santos, Sánchez-Roselló, María, Rodrigo, Vanessa, Sanz-Cervera, Juan F., Piera, Julio, Simón-Fuentes, Antonio, del Pozo, Carlos

“…The diastereoselective synthesis of cyclic β,β‐difluorinated α‐amino acid derivatives bearing a quaternary stereocenter is described. The process relies on the…”
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New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S 2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation by Fustero, Santos, Rodrigo, Vanessa, Sánchez‐Roselló, María, del Pozo, Carlos, Timoneda, Joaquín, Frizler, Maxim, Sisay, Mihiret T., Bajorath, Jürgen, Calle, Luis P., Cañada, F. Javier, Jiménez‐Barbero, Jesús, Gütschow, Michael

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Selective Formal Transesterification of Fluorinated 2-(Trimethylsilyl)ethyl α-Imino Esters Mediated by TBAF by Fustero, Santos, Sánchez-Roselló, María, Rodrigo, Vanessa, García, Amador, Catalán, Silvia, del Pozo, Carlos

“…The scope of the transesterification reaction between β-fluorinated α-imino esters and various electrophiles in the presence of TBAF as fluorine source is…”
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Solution and fluorous phase synthesis of β,β-difluorinated 1-amino-1-cyclopentane carboxylic acid derivatives by Fustero, Santos, Rodrigo, Vanessa, Sánchez-Roselló, María, Mojarrad, Fatemeh, Vicedo, Ana, Moscardó, Teresa, del Pozo, Carlos

“…An efficient protocol for the preparation of β,β-difluorinated 1-amino-1-cyclopentane carboxylic acid derivatives was developed. ▪ An efficient protocol for…”
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Asymmetric Synthesis of New β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives by Fustero, Santos, Sánchez-Roselló, Maria, Rodrigo, Vanessa, del Pozo, Carlos, Sanz-Cervera, Juan F, Simón, Antonio, Ramírez de Arellano, Carmen

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