Search Results - "Rodrigo, Glenn"

Regulation of vascular function and blood pressure by circadian variation in redox signalling by Rodrigo, Glenn C., Herbert, Karl E.

“…There is accumulating evidence that makes the link between the circadian variation in blood pressure and circadian variations in vascular contraction. The…”
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Effects of late, repetitive remote ischaemic conditioning on myocardial strain in patients with acute myocardial infarction by Arnold, J. Ranjit, P.Vanezis, Andrew, Rodrigo, Glenn C., Lai, Florence Y., Kanagala, Prathap, Nazir, Sheraz, Khan, Jamal N., Ng, Leong, Chitkara, Kamal, Coghlan, J. Gerry, Hetherington, Simon, Samani, Nilesh J., McCann, Gerald P.

“…Late, repetitive or chronic remote ischaemic conditioning (CRIC) is a potential cardioprotective strategy against adverse remodelling following ST-segment…”
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The time-of-day variation in vascular smooth muscle contractility depends on a nitric oxide signalling pathway by Denniff, M, Turrell, Helen E, Vanezis, Andrew, Rodrigo, Glenn C

“…Abstract The dip in blood pressure during the resting-period is paradoxically associated with an increase in total peripheral resistance and occurs at a time…”
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Inotropic Response of Cardiac Ventricular Myocytes to β-Adrenergic Stimulation With Isoproterenol Exhibits Diurnal Variation: Involvement of Nitric Oxide by Collins, Helen E, Rodrigo, Glenn C

“…RATIONALE:Although >10% of cardiac gene expression displays diurnal variations, little is known of their impact on excitation–contraction coupling…”
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Diurnal variation in excitation-contraction coupling is lost in the adult spontaneously hypertensive rat heart by Collins, Helen E, Turrell, Helen E, Samani, Nilesh J, Rodrigo, Glenn C

“…BACKGROUND:Excitation-contraction coupling of the normotensive rat heart exhibits a time-of-day variation in its response to isoproterenol (ISO), with a…”
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Remote ischemic preconditioning of cardiomyocytes inhibits the mitochondrial permeability transition pore independently of reduced calcium‐loading or sarcKATP channel activation by Turrell, Helen E., Thaitirarot, Chokanan, Crumbie, Hayley, Rodrigo, Glenn

“…Ischemic preconditioning (IPC) inhibits Ca2+‐loading during ischemia which contributes to cardioprotection by inhibiting mechanical injury due to…”
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Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes by Rodrigo, Glenn C, Samani, Nilesh J

“…Current cellular models of ischemic preconditioning (IPC) rely on inducing preconditioning in vitro and may not accurately represent complex pathways triggered…”
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Phenylephrine preconditioning involves modulation of cardiac sarcolemmal KATP current by PKC delta, AMPK and p38 MAPK by Turrell, Helen E, Rodrigo, Glenn C, Norman, Robert I, Dickens, Martin, Standen, Nicholas B

“…Abstract Preconditioning of hearts with the α1 -adrenoceptor agonist phenylephrine decreases infarct size and increases the functional recovery of the heart…”
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Remote ischemic preconditioning of cardiomyocytes inhibits the mitochondrial permeability transition pore independently of reduced calcium-loading or sarc K ATP channel activation by Turrell, Helen E., Thaitirarot, Chokanan, Crumbie, Hayley, Rodrigo, Glenn

“…Ischemic preconditioning (IPC) inhibits Ca2+‐loading during ischemia which contributes to cardioprotection by inhibiting mechanical injury due to…”
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Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanism by RODRIGO, Glenn C, DAVIES, Noel W, STANDEN, Nicholas B

“…We have used isolated myocytes to investigate the effects of diazoxide on sarcolemmal KATP channel (sarcoKATP) activity and action potential failure during…”
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The electrical and mechanical response of adult guinea pig and rat ventricular myocytes to ω3 polyunsaturated fatty acids by Macleod, Jennifer C, Macknight, Anthony D.C, Rodrigo, Glenn C

“…Single adult guinea-pig and rat ventricular cardiac myocytes were used to study the effects of two members of the ω3 class of polyunsaturated fatty acids,…”
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Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection by Patel, Vanlata H, Karteris, Emmanouil, Chen, Jing, Kyrou, Ioannis, Mattu, Harman S, Dimitriadis, Georgios K, Rodrigo, Glenn, Antoniades, Charalambos, Antonopoulos, Alexios, Tan, Bee K, Hillhouse, Edward W, Ng, Andre, Randeva, Harpal S

“…Orexins/hypocretins exert cardiovascular effects which are centrally mediated. In the present study, we tested whether orexins and their receptors may also act…”
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Interdependence of intracellular taurine and sodium in guinea pig heart by Suleiman, M S, Rodrigo, G C, Chapman, R A

“…The aim was to investigate the effects of raising intracellular taurine on the intracellular sodium activity (aNa1) in isolated guinea pig ventricular…”
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Role of mitochondrial re-energization and Ca influx in reperfusion injury of metabolically inhibited cardiac myocytes by RODRIGO, G, STANDEN, N

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Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes by RODRIGO, Glenn C, STANDEN, Nicholas B

“…We used isolated myocytes to investigate the role of mitochondrial re-energization and Ca2+ influx during reperfusion on hypercontracture, loss of Ca2+…”
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Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPK by Turrell, Helen E, Rodrigo, Glenn C, Norman, Robert I, Dickens, Martin, Standen, Nicholas B

“…Preconditioning of hearts with the α(1)-adrenoceptor agonist phenylephrine decreases infarct size and increases the functional recovery of the heart following…”
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The negative inotropic effect of raised extracellular potassium and caesium ions on isolated frog atrial trabeculae by Chapman, R A, Rodrigo, G C

“…The exposure of frog atrial trabeculae to Ringer solution containing an elevated K+ concentration, produces a depolarization of the membrane and a reduction of…”
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The dependence of the relaxation of tension of frog atrial-trabeculae on the sodium-calcium exchange: a voltage-clamp study by Chapman, R A, Rodrigo, G C

“…The dependence of the relaxation of tension of isolated frog atrial trabeculae, upon membrane potential, [Na]0 and [Ca]0, has been studied under voltage-clamp…”
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The dependence of the strength of sodium-depletion contractures of isolated frog atrial trabeculae on the membrane potential by Chapman, R A, Rodrigo, G C

“…When the Na bathing isolated frog atrial trabeculae voltage clamped at -80 mV is reduced, a strong contracture develops. Upon return to normal extracellular Na…”
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The Na(+)-dependence of Na(+)-activated K(+)-channels (IK(Na)) in guinea pig ventricular myocytes, is different in excised inside/out patches and cell attached patches by Rodrigo, G C

“…Single Na(+)-activated K(+)-channels were recorded from intact guinea-pig ventricular myocytes perfused with Ca-free, Mg-free Tyrode, to increase [Na+]i. The…”
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