Search Results - "Rodríguez de Lope, Angel"

Genetic Alterations Associated With Progression and Recurrence in Meningiomas by Pérez-Magán, Elisa, Campos-Martín, Yolanda, Mur, Pilar, Fiaño, Concepción, Ribalta, Teresa, García, Juan Fernando, Rey, Juan A, Rodríguez de Lope, Angel, Mollejo, Manuela, Meléndez, Bárbara

“…ABSTRACTMeningiomas are the most common primary brain tumors; they arise from the coverings of the brain. Although meningiomas are generally benign, some are…”
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Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling by Ruano, Yolanda, Mollejo, Manuela, Ribalta, Teresa, Fiaño, Concepción, Camacho, Francisca I, Gómez, Elena, de Lope, Angel Rodríguez, Hernández-Moneo, Jose-Luis, Martínez, Pedro, Meléndez, Bárbara

“…Conventional cytogenetic and comparative genomic hybridization (CGH) studies in brain malignancies have shown that glioblastoma multiforme (GBM) is…”
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Identification of survival‐related genes of the phosphatidylinositol 3′‐kinase signaling pathway in glioblastoma multiforme by Ruano, Yolanda, Mollejo, Manuela, Camacho, Francisca I., de Lope, Angel Rodríguez, Fiaño, Concepción, Ribalta, Teresa, Martínez, Pedro, Hernández‐Moneo, Jose‐Luis, Meléndez, Bárbara

“…BACKGROUND Knowledge of the molecular mechanisms involved in the biology of glioblastoma multiforme (GBM) is essential for the identification of candidate…”
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Molecular Study of Long-Term Survivors of Glioblastoma by Gene-Targeted Next-Generation Sequencing by Cantero, Diana, Rodríguez de Lope, Ángel, Moreno de la Presa, Raquel, Sepúlveda, Juan M, Borrás, José M, Castresana, Javier S, D'Haene, Nicky, García, Juan F, Salmon, Isabelle, Mollejo, Manuela, Rey, Juan A, Hernández-Laín, Aurelio, Meléndez, Bárbara

“…Abstract Glioblastoma (GBM) is the most common malignant adult primary brain tumor. Despite its high lethality, a small proportion of patients have a…”
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Craniopharyngiomas: A clinicopathological and molecular study of 52 cases - Experience in the Complejo Hospitalario de Toledo and Hospital Universitario 12 de Octubre (Madrid) by Moreno-Torres, Beatriz, Campos-Martín, Yolanda, Meléndez, Bárbara, Garcia Martin, Rosa Maria, Vicente, Almudena, Rodríguez de Lope, Ángel, Alen, José F, Mollejo, Manuela, Hernández-Laín, Aurelio

“…Craniopharyngiomas (CPs) are histologically benign tumors that are associated with high levels of morbidity. Two clinicopathological variants -…”
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Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors by Mur, Pilar, Mollejo, Manuela, Ruano, Yolanda, de Lope, Ángel Rodríguez, Fiaño, Concepción, García, Juan Fernando, Castresana, Javier S., Hernández-Laín, Aurelio, Rey, Juan A., Meléndez, Bárbara

“…Oligodendroglial tumors (OTs) are primary brain tumors that show variable clinical and biological behavior. The 1p/19q codeletion is frequent in these tumors,…”
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Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas by Pérez-Magán, Elisa, Rodríguez de Lope, Ángel, Ribalta, Teresa, Ruano, Yolanda, Campos-Martín, Yolanda, Pérez-Bautista, Gerardo, García, Juan Fernando, García-Claver, Ainoha, Fiaño, Concepción, Hernández-Moneo, José-Luis, Mollejo, Manuela, Meléndez, Bárbara

“…The majority of meningiomas are probably benign but a number of tumors display considerable histological and/or clinical aggressivity, sometimes with…”
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Tumor Surface Regularity at MR Imaging Predicts Survival and Response to Surgery in Patients with Glioblastoma by Pérez-Beteta, Julián, Molina-García, David, Ortiz-Alhambra, José A, Fernández-Romero, Antonio, Luque, Belén, Arregui, Elena, Calvo, Manuel, Borrás, José M, Meléndez, Bárbara, Rodríguez de Lope, Ángel, Moreno de la Presa, Raquel, Iglesias Bayo, Lidia, Barcia, Juan A, Martino, Juan, Velásquez, Carlos, Asenjo, Beatriz, Benavides, Manuel, Herruzo, Ismael, Revert, Antonio, Arana, Estanislao, Pérez-García, Víctor M

“…Purpose To evaluate the prognostic and predictive value of surface-derived imaging biomarkers obtained from contrast material-enhanced volumetric T1-weighted…”
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Worse Outcome in Primary Glioblastoma Multiforme With Concurrent Epidermal Growth Factor Receptor and p53 Alteration by RUANO, Yolanda, RIBALTA, Teresa, RODRIGUEZ DE LOPE, Angel, CAMPOS-MARTIN, Yolanda, FIANO, Concepcion, PEREZ-MAGAN, Elisa, HERNANDEZ-MONEO, José-Luis, MOLLEJO, Manuela, MELENDEZ, Barbara

“…Primary glioblastoma multiforme (GBM), in contrast with secondary GBM, has been associated with the presence of EGFR amplification and absence of p53 mutation…”
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The Cortical Motor System in the Domestic Pig: Origin and Termination of the Corticospinal Tract and Cortico-Brainstem Projections by del Cerro, Patricia, Rodríguez-De-Lope, Ángel, Collazos-Castro, Jorge E.

“…The anatomy of the cortical motor system and its relationship to motor repertoire in artiodactyls is for the most part unknown. We studied the origin and…”
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Morphological MRI-based features provide pretreatment survival prediction in glioblastoma by Pérez-Beteta, Julián, Molina-García, David, Martínez-González, Alicia, Henares-Molina, Araceli, Amo-Salas, Mariano, Luque, Belén, Arregui, Elena, Calvo, Manuel, Borrás, José M., Martino, Juan, Velásquez, Carlos, Meléndez-Asensio, Bárbara, de Lope, Ángel Rodríguez, Moreno, Raquel, Barcia, Juan A., Asenjo, Beatriz, Benavides, Manuel, Herruzo, Ismael, Lara, Pedro C., Cabrera, Raquel, Albillo, David, Navarro, Miguel, Pérez-Romasanta, Luis A., Revert, Antonio, Arana, Estanislao, Pérez-García, Víctor M.

“…Objectives We wished to determine whether tumor morphology descriptors obtained from pretreatment magnetic resonance images and clinical variables could…”
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Molecular Classification Defines 4 Prognostically Distinct Glioma Groups Irrespective of Diagnosis and Grade by Mur, Pilar, Mollejo, Manuela, Hernández-Iglesias, Teresa, de Lope, Ángel Rodríguez, Castresana, Javier S., García, Juan F., Fiaño, Concepción, Ribalta, Teresa, Rey, Juan A., Meléndez, Barbara

“…According to World Health Organization criteria, diffuse gliomas are divided into several histological subtypes, including astrocytomas, oligodendrogliomas,…”
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Silk-Elastin-like Polymers for Acute Intraparenchymal Treatment of the Traumatically Injured Spinal Cord: A First Systematic Experimental Approach by González, Pau, González-Fernández, Carlos, Maqueda, Alfredo, Pérez, Virginia, Escalera-Anzola, Sara, Rodríguez de Lope, Ángel, Arias, Francisco Javier, Girotti, Alessandra, Rodríguez, Francisco Javier

“…Despite the promising potential of hydrogel-based therapeutic approaches for spinal cord injury (SCI), the need for new biomaterials to design effective…”
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Neurosurgical emergency management during the lockdown period in health care regions in Spain with different COVID-19 impact: lessons learned to improve outcomes on the future waves by Gandía-González, Maria L., Viñuela-Prieto, Jose M., Barrios, Laura, Alarcón, Carlos, Arikan, Fuat, Arráez, Cinta, Domínguez, Carlos J., Alén, Jose F., Gutiérrez-González, Raquel, Horcajadas, Angel, Muñoz Hernández, Fernando, Narváez, Alejandra, Paredes, Igor, Pérez-Alfayate, Rebeca, Rodríguez de Lope, Angel, Ruiz-Juretschke, Fernando, Salge Arrieta, Freddy J., Tejada, Sonia, Tamarit, Martin, Topczewski, Thomaz, Lafuente, Jesus

“…Background COVID-19 has overloaded health care systems, testing the capacity and response in every European region. Concerns were raised regarding the impact…”
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Novel Genomic Alterations and Mechanisms Associated With Tumor Progression in Oligodendroglioma and Mixed Oligoastrocytoma by Blesa, David, Mollejo, Manuela, Ruano, Yolanda, de Lope, Angel Rodríguez, Fiaño, Concepción, Ribalta, Teresa, García, Juan Fernando, Campos-Martín, Yolanda, Hernández-Moneo, Jose-Luis, Cigudosa, Juan Cruz, Meléndez, Bárbara

“…Combined 1p/19q deletions are very prevalent in oligodendrogliomas (OGs) and, to a lesser extent, in oligoastrocytomas (OAs). These losses are associated with…”
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Ectopic craniopharyngioma and Gardner's syndrome: Case report and literature review by Álvarez Salgado, Juan Antonio, González-Llanos Fernández de Mesa, Francisco, Villaseñor Ledezma, Jorge Javier, Cañizares Méndez, Maria de Los Angeles, Paredes Sansinenea, Igor, Rodríguez de Lope-Llorca, Angel, Mollejo Villanueva, Manuela

“…Craniopharyngioma accounts for around 3% of all primary tumours of the central nervous system. It is usually located in the suprasellar region, although it may…”
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Microarray-based comparative genomic hybridization (array-CGH) as a useful tool for identifying genes involved in Glioblastoma (GB) by Ruano, Yolanda, Mollejo, Manuela, de Lope, Angel Rodríguez, Hernández-Moneo, José Luis, Martínez, Pedro, Meléndez, Bárbara

“…Alterations in the genome that lead to changes in DNA sequence copy number are a characteristic of Glioblastomas (GBs). Microarray-based comparative genomic…”
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Impact on prognosis of the regional distribution of MGMT methylation with respect to the CpG island methylator phenotype and age in glioma patients by Mur, Pilar, Rodríguez de Lope, Ángel, Díaz-Crespo, Francisco Javier, Hernández-Iglesias, Teresa, Ribalta, Teresa, Fiaño, Concepción, García, Juan Fernando, Rey, Juan Antonio, Mollejo, Manuela, Meléndez, Bárbara

“…Clinical and molecular prognostic factors in gliomas include age, IDH mutation, the glioma CpG island methylator phenotype (G-CIMP+) and promoter methylation…”
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Correction to: Morphological MRI-based features provide pretreatment survival prediction in glioblastoma by Pérez-Beteta, Julián, Molina-García, David, Martínez-González, Alicia, Henares-Molina, Araceli, Amo-Salas, Mariano, Luque, Belén, Arregui, Elena, Calvo, Manuel, Borrás, José M., Martino, Juan, Velásquez, Carlos, Meléndez-Asensio, Bárbara, de Lope, Ángel Rodríguez, Moreno, Raquel, Barcia, Juan A., Asenjo, Beatriz, Benavides, Manuel, Herruzo, Ismael, Lara, Pedro C., Cabrera, Raquel, Albillo, David, Navarro, Miguel, Pérez-Romasanta, Luis A., Revert, Antonio, Arana, Estanislao, Pérez-García, Víctor M.

“…The original version of this article, published on 15 October 2018, unfortunately contained a mistake. The following correction has therefore been made in the…”
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TP53, ATRX alterations, and low tumor mutation load feature IDH-wildtype giant cell glioblastoma despite exceptional ultra-mutated tumors by Cantero, Diana, Mollejo, Manuela, Sepúlveda, Juan M, D’Haene, Nicky, Gutiérrez-Guamán, Myriam J, Rodríguez de Lope, Ángel, Fiaño, Concepción, Castresana, Javier S, Lebrun, Laetitia, Rey, Juan A, Salmon, Isabelle, Meléndez, Bárbara, Hernández-Laín, Aurelio

“…Abstract Background Giant cell glioblastoma (gcGBM) is a rare morphological variant of IDH-wildtype (IDHwt) GBM that occurs in young adults and have a slightly…”
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