Search Results - "Rodríguez‐Macias, Gabriela"

A prognostic model for survival after salvage treatment with FLAG‐Ida +/− gemtuzumab‐ozogamicine in adult patients with refractory/relapsed acute myeloid leukaemia by Bergua, Juan M., Montesinos, Pau, Martinez‐Cuadrón, David, Fernández‐Abellán, Pascual, Serrano, Josefina, Sayas, María J., Prieto‐Fernandez, Julio, García, Raimundo, García‐Huerta, Ana J., Barrios, Manuel, Benavente, Celina, Pérez‐Encinas, Manuel, Simiele, Adriana, Rodríguez‐Macias, Gabriela, Herrera‐Puente, Pilar, Rodríguez‐Veiga, Rebeca, Martínez‐Sánchez, María P., Amador‐Barciela, María L., Riaza‐Grau, Rosalía, Sanz, Miguel A.

“…Summary The combination of fludarabine, cytarabine, idarubicin, and granulocyte colony‐stimulating factor (FLAG‐Ida) is widely used in relapsed/refractory…”
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Role of drug transport and metabolism in the chemoresistance of acute myeloid leukemia by Marin, Jose J.G, Briz, Oscar, Rodríguez-Macias, Gabriela, Díez-Martín, José L, Macias, Rocio I.R

“…Abstract Acute myeloid leukemia is a clonal but heterogeneous disease differing in molecular pathogenesis, clinical features and response to chemotherapy. This…”
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COVID‐19 coagulopathy: An in‐depth analysis of the coagulation system by Martín‐Rojas, Reyes María, Pérez‐Rus, Gloria, Delgado‐Pinos, Valeria Estefania, Domingo‐González, Amalia, Regalado‐Artamendi, Isabel, Alba‐Urdiales, Natalia, Demelo‐Rodríguez, Pablo, Monsalvo, Silvia, Rodríguez‐Macías, Gabriela, Ballesteros, Monica, Osorio‐Prendes, Santiago, Díez‐Martín, José Luis, Pascual Izquierdo, Cristina

“…Background Abnormal coagulation parameters have been reported in COVID‐19‐infected patients. Although the underlying mechanism of COVID‐19 coagulopathy remains…”
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Oral decitabine/cedazuridine versus intravenous decitabine for acute myeloid leukaemia: A randomised, crossover, registration, pharmacokinetics study by Geissler, Klaus, Koristek, Zdenek, Castillo, Teresa Bernal, Novák, Jan, Rodríguez‐Macías, Gabriela, Metzelder, Stephan K., Illes, Arpad, Mayer, Jiří, Arnan, Montserrat, Keating, Mary‐Margaret, Krauter, Jürgen, Lunghi, Monia, Fracchiolla, Nicola Stefano, Platzbecker, Uwe, Santini, Valeria, Sano, Yuri, Oganesian, Aram, Keer, Harold, Lübbert, Michael

“…Summary This study compared decitabine exposure when administered IV (DEC‐IV) at a dose of 20 mg/m2 for 5‐days with orally administered decitabine with…”
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Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab by Palomino-Cabrera, Rosalía, Tejerina, Francisco, Molero-Salinas, Andrea, Ferris, María, Veintimilla, Cristina, Catalán, Pilar, Rodríguez Macias, Gabriela, Alonso, Roberto, Muñoz, Patricia, García de Viedma, Darío, Pérez-Lago, Laura

“…The emergence of the Omicron variant of SARS-CoV-2 represented a challenge to the treatment of COVID-19 using monoclonal antibodies. Only Sotrovimab maintained…”
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Clinical utility of targeted next‐generation sequencing for the diagnosis of myeloid neoplasms with germline predisposition by Andrés‐Zayas, Cristina, Suárez‐González, Julia, Rodríguez‐Macías, Gabriela, Dorado, Nieves, Osorio, Santiago, Font, Patricia, Carbonell, Diego, Chicano, María, Muñiz, Paula, Bastos, Mariana, Kwon, Mi, Díez‐Martín, José Luis, Buño, Ismael, Martínez‐Laperche, Carolina

“…Myeloid neoplasms (MN) with germline predisposition (MNGP) are likely to be more common than currently appreciated. Many of the genes involved in MNGP are also…”
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PLZF-RAR α , NPM1-RAR α , and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review by Sobas, Marta, Talarn-Forcadell, Maria Carme, Martínez-Cuadrón, David, Escoda, Lourdes, García-Pérez, María J, Mariz, Jose, Mela-Osorio, María J, Fernández, Isolda, Alonso-Domínguez, Juan M, Cornago-Navascués, Javier, Rodríguez-Macias, Gabriela, Amutio, María E, Rodríguez-Medina, Carlos, Esteve, Jordi, Sokół, Agnieszka, Murciano-Carrillo, Thais, Calasanz, María J, Barrios, Manuel, Barragán, Eva, Sanz, Miguel A, Montesinos, Pau

“…It has been suggested that 1-2% of acute promyelocytic leukemia (APL) patients present variant rearrangements of retinoic acid receptor alpha (RARα) fusion…”
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Next Generation Cytogenetics in Myeloid Hematological Neoplasms: Detection of CNVs and Translocations by Chicano, María, Carbonell, Diego, Suárez-González, Julia, Lois, Sergio, Ballesteros-Culebras, Mercedes, Andrés-Zayas, Cristina, Muñiz, Paula, Rodríguez-Macias, Gabriela, Bastos-Oreiro, Mariana, Font, Patricia, Ballesteros, Mónica, Kwon, Mi, Anguita, Javier, Díez-Martín, José Luis, Buño, Ismael, Martínez-Laperche, Carolina

“…Conventional cytogenetics are the gold standard for the identification of chromosomal alterations recurrent in myeloid neoplasms. Some next-generation…”
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Mutation of the NPM1 gene contributes to the development of donor cell–derived acute myeloid leukemia after unrelated cord blood transplantation for acute lymphoblastic leukemia by Rodríguez-Macías, Gabriela, MD, Martínez-Laperche, Carolina, PhD, Gayoso, Jorge, MD, Noriega, Víctor, MD, Serrano, David, MD, Balsalobre, Pascual, MN, Muñoz-Martínez, Cristina, RN, Díez-Martín, José L., MD, PhD, Buño, Ismael, PhD

“…Summary Donor cell leukemia (DCL) is a rare but severe complication after allogeneic stem cell transplantation. Its true incidence is unknown because of a lack…”
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Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in adults with haematological malignancies: a phase 3, randomised, clinical trial and post-hoc efficacy analysis by Dagnew, Alemnew F, Ilhan, Osman, Lee, Won-Sik, Woszczyk, Dariusz, Kwak, Jae-Yong, Bowcock, Stella, Sohn, Sang Kyun, Rodriguez Macías, Gabriela, Chiou, Tzeon-Jye, Quiel, Dimas, Aoun, Mickael, Navarro Matilla, Maria Belen, de la Serna, Javier, Milliken, Samuel, Murphy, John, McNeil, Shelly A, Salaun, Bruno, Di Paolo, Emmanuel, Campora, Laura, López-Fauqued, Marta, El Idrissi, Mohamed, Schuind, Anne, Heineman, Thomas C, Van den Steen, Peter, Oostvogels, Lidia, Acar, Kadir, Afanasyev, Boris, Alonso Alonso, Aránzazu, Anttila, Veli-Jukka, Barba Suñol, Pere, Blesing, Norbert, Comeau, Terrance, del Campo, Teresa, Disperati, Patricia, Eek, Richard, Eom, HyeonSeok, Gaidano, Gianluca, Grosicki, Sebastian, Guillaume, Thierry, Homenda, Wojciech, Hwang, William, Ilyin, Nikolay, Johnston, Anna, Kim, Seok Jin, Kuo, Ching-Yuan, Kuvshinov, Aleksey, Lee, Dong-Gun, Lee, Jae Hoon, Lee, Je-Jung, Lepretre, Stephane, Lie, Albert Kwok-Wai, Lucchesi, Alessandro, Masood, Ahmed, Mir, Naheed, Miranda Castillo, Anna Carolina, Mullane, Kathleen, Myasnikov, Alexandr, Oña Navarrete, Raquel, Pauksens, Karlis, Peniket, Andrew, Perez de Oteyza, Jaime, Pohlreich, David, Pullon, Humphrey, Quittet, Philippe, Rodon, Philippe, Rombo, Lars, Samoylova, Olga, Sanmartin Berglund, Johan, Schattner, Ariah, Selleslag, Dominik, Sinisalo, Marjatta, Sultan, Faisal, Theunissen, Koen, Turner, Paul, Wang, Po-Nan, Yáñez San Segundo, Lucrecia, Young, Jo-Anne, Zachee, Pierre, Zaja, Francesco

“…The adjuvanted recombinant zoster vaccine (Shingrix) can prevent herpes zoster in older adults and autologous haemopoietic stem cell transplant recipients. We…”
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A Case-Control Study of Real-Life Experience with Ceftolozane-Tazobactam in Patients with Hematologic Malignancy and Pseudomonas aeruginosa Infection by Fernández-Cruz, Ana, Alba, Natalia, Semiglia-Chong, María Auxiliadora, Padilla, Belén, Rodríguez-Macías, Gabriela, Kwon, Mi, Cercenado, Emilia, Chamorro-de-Vega, Esther, Machado, Marina, Pérez-Lago, Laura, García de Viedma, Darío, Díez Martín, José Luis, Muñoz, Patricia

“…We present our experience in patients with hematologic malignancy and infection treated with ceftolozane-tazobactam. We performed a single-center case-control…”
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Next-Generation Sequencing Improves Diagnosis, Prognosis and Clinical Management of Myeloid Neoplasms by Carbonell, Diego, Suárez-González, Julia, Chicano, María, Andrés-Zayas, Cristina, Triviño, Juan Carlos, Rodríguez-Macías, Gabriela, Bastos-Oreiro, Mariana, Font, Patricia, Ballesteros, Mónica, Muñiz, Paula, Balsalobre, Pascual, Kwon, Mi, Anguita, Javier, Díez-Martín, José Luis, Buño, Ismael, Martínez-Laperche, Carolina

“…Molecular diagnosis of myeloid neoplasms (MN) is based on the detection of multiple genetic alterations using various techniques. Next-generation sequencing…”
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Whole-exome sequencing reveals acquisition of mutations leading to the onset of donor cell leukemia after hematopoietic transplantation: a model of leukemogenesis by Suárez-González, Julia, Martínez-Laperche, Carolina, Martínez, Nerea, Rodríguez-Macías, Gabriela, Kwon, Mi, Balsalobre, Pascual, Carbonell, Diego, Chicano, María, Serrano, David, Triviño, Juan Carlos, Piris, Miguel Ángel, Gayoso, Jorge, Díez-Martín, José Luis, Buño, Ismael

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Practical Considerations for Treatment of Relapsed/Refractory FLT3-ITD Acute Myeloid Leukaemia with Quizartinib: Illustrative Case Reports by Martínez-Cuadrón, David, Rodríguez-Macías, Gabriela, Rodríguez-Veiga, Rebeca, Boluda, Blanca, Montesinos, Pau

“…Quizartinib is a tyrosine kinase inhibitor selectively targeting the FMS-like tyrosine kinase 3 (FLT3) receptor that has been developed for the treatment of…”
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Implementation of a hospital-at-home (HAH) unit for hematological patients during the COVID-19 pandemic: safety and feasibility by Gómez-Centurión, Ignacio, Oarbeascoa, Gillen, García, María Carmen, López Fresneña, María Carmen, Martínez Carreño, María Josefa, Escudero Vilaplana, Vicente, González-Haba, Eva, Bailén, Rebeca, Dorado, Nieves, Juárez, Luis Miguel, Rodríguez Macías, Gabriela, Font López, Patricia, Encinas, Cristina, Bastos-Oreiro, Mariana, Anguita, Javier, Sanjurjo, María, Díez-Martin, José Luis, Kwon, Mi

“…Background “Hospital-at-home” (HAH) programs have been shown to optimize resource utilization, shorten hospitalization and prevent nosocomial infection…”
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A retrospective cohort of invasive fusariosis in the era of antimould prophylaxis by Fernández-Cruz, Ana, Semiglia, María Auxiliadora, Guinea, Jesús, Martínez-Jiménez, María del Carmen, Escribano, Pilar, Kwon, Mi, Rodríguez-Macías, Gabriela, Chamorro-de-Vega, Esther, Rodríguez-González, Carmen, Navarro, Raquel, Galar, Alicia, Sánchez-Carrillo, Carlos, Díez-Martín, José Luis, Muñoz, Patricia

“…Abstract Mould-active prophylaxis is affecting the epidemiology of invasive mycoses in the form of a shift toward less common entities such as fusariosis. We…”
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Genetic biomarkers identify a subgroup of high-risk patients within low-risk NPM1-mutated acute myeloid leukemia by Carbonell, Diego, Suárez-González, Julia, Chicano, María, Andrés-Zayas, Cristina, Díez-Díez, Miriam, Rodríguez-Macías, Gabriela, Muñiz, Paula, Kwon, Mi, Anguita, Javier, Díez-Martín, José Luis, Buño, Ismael, Martínez-Laperche, Carolina

“…Although acute myeloid leukemia (AML) with NPM1 mut /FLT3-ITD neg is a low-risk entity, its relapse rate remains high. Out of 333 AML patients, 27 were NPM1…”
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Role of Intracellular Drug Disposition in the Response of Acute Myeloid Leukemia to Cytarabine and Idarubicin Induction Chemotherapy by Rodríguez-Macías, Gabriela, Briz, Oscar, Cives-Losada, Candela, Chillón, María C, Martínez-Laperche, Carolina, Martínez-Arranz, Ibon, Buño, Ismael, González-Díaz, Marcos, Díez-Martín, José L, Marin, Jose J G, Macias, Rocio I R

“…Despite its often low efficacy and high toxicity, the standard treatment for acute myeloid leukemia (AML) is induction chemotherapy with cytarabine and…”
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Novel Candidate loci and Pathogenic Germline Variants Involved in Familial Hematological Malignancies Revealed by Whole-Exome Sequencing by Andrés-Zayas, Cristina, Suárez-González, Julia, Chicano-Lavilla, María, Bastos Oreiro, Mariana, Rodríguez-Macías, Gabriela, Font López, Patricia, Osorio Prendes, Santiago, Oarbeascoa Royuela, Gillen, García Ramírez, Patricia, Nieves Salgado, Rocío, Gómez-Centurión, Ignacio, Carbonell Muñoz, Diego, Muñiz, Paula, Kwon, Mi, Díez-Martín, José Luis, Buño, Ismael, Martínez-Laperche, Carolina

“…The familial occurrence of hematological malignancies has been underappreciated. Recent studies suggest that up to 15% of adults with myeloid neoplasms carry…”
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Clinical outcomes after CPX‐351 in patients with high‐risk acute myeloid leukemia: A comparison with a matched cohort from the Spanish PETHEMA registry by Bernal, Teresa, Moreno, Ainhoa Fernández, de LaIglesia, Almudena, Benavente, Celina, García‐Noblejas, Ana, Belmonte, Daniel García, Riaza, Rosalía, Salamero, Olga, Foncillas, Maria Angeles, Roldán, Alicia, Concepción, Víctor Noriega, González, Laura Llorente, Bergua Burgués, Juan Miguel, Lorente de Uña, Soraya, Rodríguez‐Macías, Gabriela, de la Fuente Burguera, Adolfo, García Pérez, Maria José, López‐Lorenzo, Jose Luis, Martínez, Pilar, Aláez, Concepción, Callejas, Marta, Martínez‐Chamorro, Carmen, Roca, José Rifón, Barciela, Lourdes Amador, Mena Durán, Armando V., Gómez Correcha, Karoll, Lavilla Rubira, Esperanza, Amigo, María Luz, Vall‐llovera, Ferran, Garrido, Ana, García‐Fortes, María, de Miguel Llorente, Dunia, Leonardo, Anastasia Aules, Cervero, Carlos, Jordá, Rosa Coll, Pérez‐Encinas, Manuel M., Zarzuela, Marta Polo, Figuera, Angela, Rad, Guillermo, Martínez‐Cuadrón, David, Montesinos, Pau

“…Background CPX‐351 is approved for the treatment of therapy related acute myeloid leukemia (t‐AML) and AML with myelodysplastic related changes (MRC‐AML). The…”
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