A Latin American survey on demographic aspects of hospitalized, decompensated cirrhotic patients and the resources for their management

Liver cirrhosis is a major cause of mortality worldwide. Adequate diagnosis and treatment of decompensating events requires of both medical skills and updated technical resources. The objectives of this study were to search the demographic profile of hospitalized cirrhotic patients in a group of Lat...

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Published in:Annals of hepatology Vol. 19; no. 4; pp. 396 - 403
Main Authors: Vorobioff, Julio D., Contreras, Fernando, Tanno, Federico, Hernández, Lucía, Bessone, Fernando, Colombato, Luis, Adi, José, Fassio, Eduardo, Felgueres, Mirta, Fernández, Guillermo, Gaite, Luis, Gibelli, Diana, Darrichon, Hernán Gómez, Lafage, Matías, Lombardo, Daniel, López, Susana, Mateo, Alejandro, Mendizábal, Manuel, Pecoraro, Julieta, Ruf, Andrés, Ruiz, Pablo, Severini, Javier, Stieben, Teodoro, Sixto, Marcela, Zárate, Fabián, Barraza, Sergio de la Barra, Sierra, Irene Donoso, Pacheco, Violeta Rivas, Roblero, Juan P., Rojas, Juan O., González, Patricio Ruiz, Rodríguez, Diego San Martín, Sierralta, Armando, Manchego, Alvaro Urzúa, Valdes, Eliana, Yaquich, Pamela, Wolff, Rodrigo, Valdivia, Flor Beltran, Gallegos, Roxana C., Galloso, Rocío, Marcelo, Julio S., Montes, Pedro, Tenorio, Laura, Veramendi, Isabel, Alava, Elizabeth, Armijos, Ximena, Benalcazar, Gonzalo, Carrera, Enrique, Pazmiño, Galo F., Díaz, Eduardo Marriott, Garassini, Miguel, Marrero, Rosalía P., Infante, Mirta, Suárez, Dayron Páez, Gutiérrez, José C., Reyes, Carmen M. Villadoniga, Serrano, Yoel M., Hernández, Rivardo Hernández, Martínez, Orelvis Martínez, González, Teresita Pérez, Andara, María T., Hernández, Marco Sánchez, Gerona, Solange, García, Iván, Tijera, Fátima de la, López, Edmundo Pessoa, Torres, Kenia, Garzón, Martín
Format: Journal Article
Language:English
Published: Mexico Elsevier España, S.L.U 01-07-2020
Elsevier
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Summary:Liver cirrhosis is a major cause of mortality worldwide. Adequate diagnosis and treatment of decompensating events requires of both medical skills and updated technical resources. The objectives of this study were to search the demographic profile of hospitalized cirrhotic patients in a group of Latin American hospitals and the availability of expertise/facilities for the diagnosis and therapy of decompensation episodes. A cross sectional, multicenter survey of hospitalized cirrhotic patients. 377 patients, (62% males; 58±11 years) (BMI>25, 57%; diabetes 32%) were hospitalized at 65 centers (63 urbans; 57 academically affiliated) in 13 countries on the survey date. Main admission causes were ascites, gastrointestinal bleeding, hepatic encephalopathy and spontaneous bacterial peritonitis/other infections. Most prevalent etiologies were alcohol-related (AR) (40%); non-alcoholic-steatohepatitis (NASH) (23%), hepatitis C virus infection (HCV) (7%) and autoimmune hepatitis (AIH) (6%). The most frequent concurrent etiologies were AR+NASH. Expertise and resources in every analyzed issue were highly available among participating centers, mostly accomplishing valid guidelines. However, availability of these facilities was significantly higher at institutions located in areas with population>500,000 (n=45) and in those having a higher complexity level (Gastrointestinal, Liver and Internal Medicine Departments at the same hospital (n=22). The epidemiological etiologic profile in hospitalized, decompensated cirrhotic patients in Latin America is similar to main contemporary emergent agents worldwide. Medical and technical resources are highly available, mostly at great population urban areas and high complexity medical centers. Main diagnostic and therapeutic approaches accomplish current guidelines recommendations.
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ISSN:1665-2681
2659-5982
DOI:10.1016/j.aohep.2020.03.007