Search Results - "Rodolis, Maria T"
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Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY
Published in Chemical communications (Cambridge, England) (07-11-2014)“…The pacidamycin and muraymycin uridyl peptide antibiotics show some structural resemblance to an Arg-Trp-x-x-Trp sequence motif for protein-protein interaction…”
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Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage ϕX174 lysis protein E, and cationic antibacterial peptides
Published in Bioorganic & medicinal chemistry (15-12-2016)“…[Display omitted] This review covers recent developments in the inhibition of translocase MraY and related phospho-GlcNAc transferases WecA and TagO, and…”
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3
Sugars Require Rigid Multivalent Displays for Activation of Mouse Sperm Acrosomal Exocytosis
Published in Biochemistry (Easton) (06-06-2017)“…As a prerequisite to mammalian fertilization, the sperm acrosomal vesicle fuses with the plasma membrane and the acrosome contents are exocytosed. Induction…”
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Glycopolymer induction of mouse sperm acrosomal exocytosis shows highly cooperative self-antagonism
Published in Biochemical and biophysical research communications (03-06-2016)“…Identifying inducers of sperm acrosomal exocytosis (AE) to understand sperm functionality is important for both mechanistic and clinical studies in mammalian…”
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Identification of a Novel Inhibition Site in Translocase MraY Based upon the Site of Interaction with Lysis Protein E from Bacteriophage ϕX174
Published in Chembiochem : a European journal of chemical biology (16-06-2014)“…Translocase MraY is the site of action of lysis protein E from bacteriophage ϕX174. Previous genetic studies have shown that mutation F288L in transmembrane…”
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Journal Article -
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Identification of a Novel Inhibition Site in Translocase MraY Based upon the Site of Interaction with Lysis Protein E from Bacteriophage X174
Published in Chembiochem : a European journal of chemical biology (16-06-2014)“…Translocase MraY is the site of action of lysis protein E from bacteriophage X174. Previous genetic studies have shown that mutation F288L in transmembrane…”
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Journal Article -
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Interaction of translocase mray with the antibacterial e protein from bacteriophage φx174
Published 01-01-2013“…The widespread use of antibiotics has played a significant role in the emergence of resistant bacteria. It is of great interest and need to develop novel,…”
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Dissertation