Search Results - "Rodnight, Richard"

Morphological plasticity of rodent astroglia by Rodnight, Richard Burnard, Gottfried, Carmem

“…In the past two decades, there has been an explosion of research on the role of neuroglial interactions in the control of brain homeostasis in both…”
Get full text

Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid by Cechin, Sirlene R, Dunkley, Peter R, Rodnight, Richard

“…We studied pathways involved in the proliferation of rat C6 glioma cells induced by lysophosphatidic acid (LPA), a phospholipid with diverse biological…”
Get full text

Extracellular ATP stimulates an inhibitory pathway towards growth factor‐induced cRaf‐1 and MEKK activation in astrocyte cultures by Lenz, Guido, Gonçalves, Daniela, Luo, Zhijun, Avruch, Joseph, Rodnight, Richard, Neary, Joseph T.

“…ATP, acting via P2Y, G protein‐coupled receptors (GPCRs), is a mitogenic signal and also synergistically enhances fibroblast growth factor‐2 (FGF‐2)‐induced…”
Get full text

Astrocyte stellation in saline media lacking bicarbonate: possible relation to intracellular pH and tyrosine phosphorylation by Cechin, Sirlene R, Gottfried, Carmem, Prestes, Cristina C, Andrighetti, Leticia, Wofchuk, Susana T, Rodnight, Richard

“…Primary cultures of astrocytes exhibit a polygonal morphology, but on treatment with agents that increase cAMP they change to stellate cells. We found that…”
Get full text

P2X7 receptors stimulate AKT phosphorylation in astrocytes by Jacques‐Silva, Maria C, Rodnight, Richard, Lenz, Guido, Liao, Zhongji, Kong, Qiongman, Tran, Minh, Kang, Yuan, Gonzalez, Fernando A, Weisman, Gary A, Neary, Joseph T

“…Emerging evidence indicates that nucleotide receptors are widely expressed in the nervous system. Here, we present evidence that P2Y and P2X receptors,…”
Get full text

Extracellular S100B protein modulates ERK in astrocyte cultures by GONCALVES, D. S, LENZ, G, KARL, J, GONCALVES, C. A, RODNIGHT, R

Get full text

P2X 7 receptors stimulate AKT phosphorylation in astrocytes by Jacques‐Silva, Maria C, Rodnight, Richard, Lenz, Guido, Liao, Zhongji, Kong, Qiongman, Tran, Minh, Kang, Yuan, Gonzalez, Fernando A, Weisman, Gary A, Neary, Joseph T

“…Emerging evidence indicates that nucleotide receptors are widely expressed in the nervous system. Here, we present evidence that P2Y and P2X receptors,…”
Get full text

P 2Y purinoceptor subtypes recruit different Mek activators in astrocytes by Lenz, Guido, Gottfried, Carmem, Luo, Zhijun, Avruch, Joseph, Rodnight, Richard, Nie, Wie‐Jia, Kang, Yuan, Neary, Joseph T

“…Extracellular ATP can function as a glial trophic factor as well as a neuronal transmitter. In astrocytes, mitogenic signalling by ATP is mediated by…”
Get full text

P2Y purinoceptor subtypes recruit different Mek activators in astrocytes by Lenz, Guido, Gottfried, Carmem, Luo, Zhijun, Avruch, Joseph, Rodnight, Richard, Nie, Wie‐Jia, Kang, Yuan, Neary, Joseph T

“…Extracellular ATP can function as a glial trophic factor as well as a neuronal transmitter. In astrocytes, mitogenic signalling by ATP is mediated by…”
Get full text

Immunocontent and secretion of S100B in astrocyte cultures from different brain regions in relation to morphology by Pinto, Silvana S., Gottfried, Carmem, Mendez, Andreas, Gonçalves, Daniela, Karl, Juliana, Gonçalves, Carlos A., Wofchuk, Susana, Rodnight, Richard

“…Primary astrocyte cultures prepared from neonatal hippocampus, cerebral cortex and cerebellum were morphologically distinct. Cells from hippocampus and cortex…”
Get full text

Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines by MORRONE, Fernanda B, JACQUES-SILVA, Maria C, HORN, Ana P, BERNARDI, Andressa, SCHWARTSMANN, Gilberto, RODNIGHT, Richard, LENZ, Guido

“…Extracellular purines (adenosine triphosphate (ATP), adenosine 5'-diphosphate (ADP) and adenosine) and pyrimidines (uridine 5'-triphosphate (UTP) and UDP) are…”
Get full text

P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes by Lenz, G, Gottfried, C, Luo, Z, Avruch, J, Rodnight, R, Nie, W J, Kang, Y, Neary, J T

“…Extracellular ATP can function as a glial trophic factor as well as a neuronal transmitter. In astrocytes, mitogenic signalling by ATP is mediated by…”
Get full text

ERK, PKC and PI3K/Akt pathways mediate extracellular ATP and adenosine-induced proliferation of U138-MG human glioma cell line by Jacques-Silva, Maria C, Bernardi, Andressa, Rodnight, Richard, Lenz, Guido

“…Extracellular nucleotides and nucleosides induce proliferation in a set of human glioma cell lines. In this study we investigate the signal transduction…”
Get more information

An Unconventional Journey to Neuroscience by Rodnight, Richard

“…After a grammar school education in the interwar years, in 1938, I obtained employment as a medical laboratory technician. My career as a technician lasted…”
Get full text

Regulation of protein phosphorylation in astrocyte cultures by external calcium ions: specific effects on the phosphorylation of glial fibrillary acidic protein (GFAP), vimentin and heat shock protein 27 (HSP27) by Gottfried, Carmem, Valentim, Lauren, Salbego, Christianne, Karl, Juliana, Wofchuk, Susana T, Rodnight, Richard

“…The effect of external Ca 2+ ([Ca 2+] e) on the incorporation of [ 32 P ] into total protein, cytoskeletal proteins and the heat shock protein HSP27, was…”
Get full text

Lithium treatment causes gliosis and modifies the morphology of hippocampal astrocytes in rats by Rocha, Elizabete, Achaval, Maltide, Santos, Paula, Rodnight, Richard

“…THE biological basis of the clinical efficacy of lithium in the treatment of mental illness has been extensively studied in neurones, but little is known about…”
Get full text

Chronic administration of lithium chloride increases immunodetectable glial fibrillary acidic protein in the rat hippocampus by Rocha, E, Rodnight, R

“…We studied the effect of treating rats with lithium salts on the content and in vitro phosphorylation rate of the astrocyte cell marker, glial fibrillary…”
Get more information

The dephosphorylation of glial fibrillary acidic protein (GFAP) in the immature rat hippocampus is catalyzed mainly by a type 1 protein phosphatase by Vinadé, Lucia, Rodnight, Richard

“…We used protein phosphatase inhibitors to study the phosphatase activity involved in the dephosphorylation of the astrocyte marker glial fibrillary acidic…”
Get full text

The mGluR stimulating GFAP phosphorylation in immature hippocampal slices has some properties of a group II receptor by Kommers, Trícia, Rodnight, Richard, Oppelt, Daniela, Oliveira, Diogo, Wofchuk, Susana

“…IN a previous study we showed that phosphorylation of the astrocytic marker glial fibrillary acidic protein (GFAP) in hippocampal slices from immature rats…”
Get full text

GFAP phosphorylation studied in digitonin-permeabilized astrocytes: standardization of conditions by Karl, Juliana, Gottfried, Carmem, Tramontina, Francine, Dunkley, Peter, Rodnight, Richard, Gonçalves, Carlos Alberto

“…Cycles of assembly/disassembly of the intermediate filaments of astrocytes are modulated by the phosphorylation of glial fibrillary acidic protein (GFAP). The…”
Get full text