Search Results - "Rodgers, Raymond J."

RNAseq analysis of oocyte maturation from the germinal vesicle stage to metaphase II in pig and human by Tang, Feng, Hummitzsch, Katja, Rodgers, Raymond J

“…During maturation oocytes at the germinal vesicle (GV) stage progress to metaphase II (MII). However, during in vitro maturation a proportion often fail to…”
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Transcriptome comparisons identify new cell markers for theca interna and granulosa cells from small and large antral ovarian follicles by Hatzirodos, Nicholas, Hummitzsch, Katja, Irving-Rodgers, Helen F, Rodgers, Raymond J

“…In studies using isolated ovarian granulosa and thecal cells it is important to assess the degree of cross contamination. Marker genes commonly used for…”
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Development of mammalian ovary by Smith, Peter, Wilhelm, Dagmar, Rodgers, Raymond J

“…Pre-natal and early post-natal ovarian development has become a field of increasing importance over recent years. The full effects of perturbations of ovarian…”
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Molecular Mechanisms of Insulin Resistance in Polycystic Ovary Syndrome: Unraveling the Conundrum in Skeletal Muscle? by Stepto, Nigel K, Moreno-Asso, Alba, McIlvenna, Luke C, Walters, Kirsty A, Rodgers, Raymond J

“…Abstract Context Polycystic ovary syndrome (PCOS) is a common endocrine condition affecting 8% to 13% of women across the lifespan. PCOS affects reproductive,…”
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Transcript abundance of stromal and thecal cell related genes during bovine ovarian development by Hatzirodos, Nicholas, Hummitzsch, Katja, Irving-Rodgers, Helen F, Breen, James, Perry, Viv E A, Anderson, Richard A, Rodgers, Raymond J

“…Movement and expansion of mesonephric-derived stroma appears to be very important in the development of the ovary. Here, we examined the expression of 24 genes…”
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Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes by Hatzirodos, Nicholas, Irving-Rodgers, Helen F, Hummitzsch, Katja, Harland, Margaret L, Morris, Stephanie E, Rodgers, Raymond J

“…At later stages of folliculogenesis, the mammalian ovarian follicle contains layers of epithelial granulosa cells surrounding an antral cavity. During follicle…”
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Transcriptome profiling of the theca interna from bovine ovarian follicles during atresia by Hatzirodos, Nicholas, Irving-Rodgers, Helen F, Hummitzsch, Katja, Rodgers, Raymond J

“…The theca interna is a specialized stromal layer that envelops each growing ovarian follicle. It contains capillaries, fibroblasts, immune cells and the…”
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A new model of development of the mammalian ovary and follicles by Hummitzsch, Katja, Irving-Rodgers, Helen F, Hatzirodos, Nicholas, Bonner, Wendy, Sabatier, Laetitia, Reinhardt, Dieter P, Sado, Yoshikazu, Ninomiya, Yoshifumi, Wilhelm, Dagmar, Rodgers, Raymond J

“…Ovarian follicular granulosa cells surround and nurture oocytes, and produce sex steroid hormones. It is believed that during development the ovarian surface…”
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Transcriptome profiling of granulosa cells from bovine ovarian follicles during atresia by Hatzirodos, Nicholas, Hummitzsch, Katja, Irving-Rodgers, Helen F, Harland, Margaret L, Morris, Stephanie E, Rodgers, Raymond J

“…The major function of the ovary is to produce oocytes for fertilisation. Oocytes mature in follicles surrounded by nurturing granulosa cells and all are…”
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Transcriptome profiling of the theca interna in transition from small to large antral ovarian follicles by Hatzirodos, Nicholas, Hummitzsch, Katja, Irving-Rodgers, Helen F, Rodgers, Raymond J

“…The theca interna layer of the ovarian follicle forms during the antral stage of follicle development and lies adjacent to and directly outside the follicular…”
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Genes in loci genetically associated with polycystic ovary syndrome are dynamically expressed in human fetal gonadal, metabolic and brain tissues by Azumah, Rafiatu, Hummitzsch, Katja, Anderson, Richard A, Rodgers, Raymond J

“…Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, affecting around 10% of women of reproductive age, with infertility, depression or anxiety,…”
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Isolation, culture, and characterisation of bovine ovarian fetal fibroblasts and gonadal ridge epithelial-like cells and comparison to their adult counterparts by Liu, Menghe, Hummitzsch, Katja, Bastian, Nicole A, Hartanti, Monica D, Wan, Qianhui, Irving-Rodgers, Helen F, Anderson, Richard A, Rodgers, Raymond J

“…During ovarian development, gonadal ridge epithelial-like (GREL) cells arise from the epithelial cells of the ventral surface of the mesonephros. They…”
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Morphometric analyses and gene expression related to germ cells, gonadal ridge epithelial-like cells and granulosa cells during development of the bovine fetal ovary by Hummitzsch, Katja, Hatzirodos, Nicholas, Irving-Rodgers, Helen F, Hartanti, Monica D, Perry, Viv E A, Anderson, Richard A, Rodgers, Raymond J

“…Cells on the surface of the mesonephros give rise to replicating Gonadal Ridge Epithelial-Like (GREL) cells, the first somatic cells of the gonadal ridge…”
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Could perturbed fetal development of the ovary contribute to the development of polycystic ovary syndrome in later life? by Hartanti, Monica D, Rosario, Roseanne, Hummitzsch, Katja, Bastian, Nicole A, Hatzirodos, Nicholas, Bonner, Wendy M, Bayne, Rosemary A, Irving-Rodgers, Helen F, Anderson, Richard A, Rodgers, Raymond J

“…Polycystic ovary syndrome (PCOS) affects around 10% of young women, with adverse consequences on fertility and cardiometabolic outcomes. PCOS appears to result…”
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Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production by Glister, Claire, Satchell, Leanne, Bathgate, Ross A D, Wade, John D, Dai, Yanzhenzi, Ivell, Richard, Anand-Ivell, Ravinder, Rodgers, Raymond J, Knight, Philip G

“…Bone morphogenetic proteins (BMPs) are firmly implicated as intra-ovarian regulators of follicle development and steroidogenesis. Here we report a microarray…”
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Transcriptomal profiling of bovine ovarian granulosa and theca interna cells in primary culture in comparison with their in vivo counterparts by Hatzirodos, Nicholas, Glister, Claire, Hummitzsch, Katja, Irving-Rodgers, Helen F, Knight, Philip G, Rodgers, Raymond J

“…In vitro culture of ovarian granulosa cells and theca cells has been very important for our understanding of their function and regulation. One of the most…”
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Bone Morphogenetic Protein-4 (BMP4): A Paracrine Regulator of Human Adrenal C19 Steroid Synthesis by Rege, Juilee, Nishimoto, Hiromi Koso, Nishimoto, Koshiro, Rodgers, Raymond J, Auchus, Richard J, Rainey, William E

“…Bone morphogenetic proteins (BMPs) comprise one of the largest subgroups in the TGF-β ligand superfamily. We have identified a functional BMP system equipped…”
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Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development by Azumah, Rafiatu, Hummitzsch, Katja, Hartanti, Monica D, St John, Justin C, Anderson, Richard A, Rodgers, Raymond J

“…Polycystic Ovary Syndrome (PCOS) is a multifactorial syndrome with reproductive, endocrine, and metabolic symptoms, affecting about 10% women of reproductive…”
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Transforming Growth Factor Beta 1 Alters Glucose Uptake but Not Insulin Signalling in Human Primary Myotubes From Women With and Without Polycystic Ovary Syndrome by McIlvenna, Luke C, Patten, Rhiannon K, McAinch, Andrew J, Rodgers, Raymond J, Stepto, Nigel K, Moreno-Asso, Alba

“…Women with polycystic ovary syndrome (PCOS), commonly have profound skeletal muscle insulin resistance which can worsen other clinical features. The…”
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Expression levels of the selenium-uptake receptor LRP8, the antioxidant selenoprotein GPX1 and steroidogenic enzymes correlate in granulosa cells by Hummitzsch, Katja, Kelly, Jasmine E, Hatzirodos, Nicholas, Bonner, Wendy M, Tang, Feng, Harris, Hugh H, Rodgers, Raymond Joseph

“…Reactive oxygen species (ROS) are a by-product of the activity of cytochrome P450 steroidogenic enzymes. Antioxidant enzymes protect against ROS damage. To…”
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