Search Results - "Rodgers, James D"

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms by Quintás-Cardama, Alfonso, Vaddi, Kris, Liu, Phillip, Manshouri, Taghi, Li, Jun, Scherle, Peggy A, Caulder, Eian, Wen, Xiaoming, Li, Yanlong, Waeltz, Paul, Rupar, Mark, Burn, Timothy, Lo, Yvonne, Kelley, Jennifer, Covington, Maryanne, Shepard, Stacey, Rodgers, James D, Haley, Patrick, Kantarjian, Hagop, Fridman, Jordan S, Verstovsek, Srdan

“…Constitutive JAK2 activation in hematopoietic cells by the JAK2V617F mutation recapitulates myeloproliferative neoplasm (MPN) phenotypes in mice, establishing…”
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Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050 by Fridman, Jordan S, Scherle, Peggy A, Collins, Robert, Burn, Timothy C, Li, Yanlong, Li, Jun, Covington, Maryanne B, Thomas, Beth, Collier, Paul, Favata, Margaret F, Wen, Xiaoming, Shi, Jack, McGee, Ryan, Haley, Patrick J, Shepard, Stacey, Rodgers, James D, Yeleswaram, Swamy, Hollis, Greg, Newton, Robert C, Metcalf, Brian, Friedman, Steven M, Vaddi, Kris

“…Inhibiting signal transduction induced by inflammatory cytokines offers a new approach for the treatment of autoimmune diseases such as rheumatoid arthritis…”
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Preclinical Evaluation of Local JAK1 and JAK2 Inhibition in Cutaneous Inflammation by Fridman, Jordan S., Scherle, Peggy A., Collins, Robert, Burn, Timothy, Neilan, Claire L., Hertel, Denise, Contel, Nancy, Haley, Patrick, Thomas, Beth, Shi, Jack, Collier, Paul, Rodgers, James D., Shepard, Stacey, Metcalf, Brian, Hollis, Gregory, Newton, Robert C., Yeleswaram, Swamy, Friedman, Steven M., Vaddi, Kris

“…JAKs are required for signaling initiated by several cytokines (e.g., IL-4, IL-12, IL-23, thymic stromal lymphopoietin (TSLP), and IFNγ) implicated in the…”
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Treatment methods for the remediation of nitroaromatic explosives by Rodgers, James D, Bunce, Nigel J

“…The production and use of nitroaromatic explosives for military operations have resulted in their dissemination into the environment, where their presence in…”
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Electrochemical Oxidation of Chlorinated Phenols by Rodgers, James D, Jedral, Wojciech, Bunce, Nigel J

“…Electrochemical oxidation has been proposed as a remediation method for chlorinated phenols but is hampered by anode fouling. In this work we explore the…”
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Combined Inhibition of Janus Kinase 1/2 for the Treatment of JAK2V617F-Driven Neoplasms: Selective Effects on Mutant Cells and Improvements in Measures of Disease Severity by Liu, Phillip C C, Caulder, Eian, Li, Jun, Waeltz, Paul, Margulis, Alex, Wynn, Richard, Becker-Pasha, Mary, Li, Yanlong, Crowgey, Erin, Hollis, Gregory, Haley, Patrick, Sparks, Richard B, Combs, Andrew P, Rodgers, James D, Burn, Timothy C, Vaddi, Kris, Fridman, Jordan S

“…Purpose: Deregulation of the Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway is a hallmark for the Philadelphia…”
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Differentiating nursing leadership and management competencies by Jennings, Bonnie Mowinski, Scalzi, Cynthia C., Rodgers, James D., Keane, Anne

“…As the foundation of evaluating content for nursing leadership and administration courses, leadership and management competencies were identified from a…”
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Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1 by Corbett, J W, Ko, S S, Rodgers, J D, Jeffrey, S, Bacheler, L T, Klabe, R M, Diamond, S, Lai, C M, Rabel, S R, Saye, J A, Adams, S P, Trainor, G L, Anderson, P S, Erickson-Viitanen, S K

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Efficient Synthesis of 5-(Bromomethyl)- and 5-(Aminomethyl)-1-THP-Indazole by Sun, Jung-Hui, Teleha, Christopher A, Yan, Jia-Sheng, Rodgers, James D, Nugiel, David A

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Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors by Patel, Mona, McHugh, Robert J, Cordova, Beverly C, Klabe, Ronald M, Erickson-Viitanen, Susan, Trainor, George L, Rodgers, James D

“…A series of 3,3-disubstituted quinoxalinones was prepared and evaluated as HIV-1 reverse transcriptase inhibitors. The N-allyl ( 6b and 6f),…”
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Maternal Household Services and Children by Baum, Charles L., Rodgers, James D.

“…Forensic economists in wrongful death cases are often asked to calculate the present value of household services a decedent otherwise would have provided. In…”
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Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors by Corbett, Jeffrey W, Ko, Soo S, Rodgers, James D, Gearhart, Lisa A, Magnus, Nicholas A, Bacheler, Lee T, Diamond, Sharon, Jeffrey, Susan, Klabe, Ronald M, Cordova, Beverly C, Garber, Sena, Logue, Kelly, Trainor, George L, Anderson, Paul S, Erickson-Viitanen, Susan K

“…A series of 4-alkenyl and 4-alkynyl-3,4-dihydro-4-(trifluoromethyl)-2-(1H)-quinazolinones were found to be potent non-nucleoside reverse transcriptase…”
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An Updated History of the National Association of Forensic Economics: 2002–2014 by Rodgers, James D., Weinstein, Marc A.

“…The National Association of Forensic Economics (NAFE) has approximately 650 members across the United States and in other countries. While the association has…”
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Electrochemical Treatment of 2,4,6-Trinitrotoluene and Related Compounds by Rodgers, James D, Bunce, Nigel J

“…This work involves electrolysis of nitrotoluene congeners, which are persistent pollutants that enter the environment as a consequence of their manufacture and…”
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Synthesis and evaluation of novel quinolinones as HIV-1 reverse transcriptase inhibitors by PATEL, Mona, MCHUGH, Robert J, CORDOVA, Beverly C, KLABE, Ronald M, BACHELER, Lee T, ERICKSON-VIITANEN, Susan, RODGERS, James D

“…A series of 4,4-disubstituted quinolinones was prepared and evaluated as HIV-1 reverse transcriptase inhibitors. The C-3 substituted compound 9h displayed…”
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Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) Derivatives. 3 by Breslin, Henry J, Kukla, Michael J, Ludovici, Donald W, Mohrbacher, Richard, Ho, Winston, Miranda, Milton, Rodgers, James D, Hitchens, T. Kevin, Leo, Gregory

“…4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2 (1H)-ones (TIBO), 1, have been shown to significantly inhibit HIV-1 replication in vitro by…”
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Handling Taxes in Employment Law Cases by Rodgers, James D.

“…Abstract No abstract available…”
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Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TlBO) Derivatives. 4 by Ho, Winston, Kukla, Michael J, Breslin, Henry J, Ludovici, Donald W, Grous, Philip P, Diamond, Craig J, Miranda, Milton, Rodgers, James D, Ho, Chih Y

“…In previous papers, we have described the discovery of a new series of compounds, 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1 H)- ones,…”
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Valuing Losses of Pension Benefits by Rodgers, James D.

“…Abstract No abstract available…”
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4,1-Benzoxazepinone analogues of efavirenz (Sustiva™) as HIV-1 reverse transcriptase inhibitors by Cocuzza, Anthony J., Chidester, Dennis R., Cordova, Beverly C., Klabe, Ronald M., Jeffrey, Susan, Diamond, Sharon, Weigelt, Carolyn A., Ko, Soo S., Bacheler, Lee T., Erickson-Viitanen, Susan K., Rodgers, James D.

“…A series of 4,1-benzoxazepinone analogues of efavirenz (Sustiva™) as potent NNRTIs has been discovered. The cis-3-alkylbenzoxazepinones are more potent then…”
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