Search Results - "Roderick, J."

Telomeres: protecting chromosomes against genome instability by Karlseder, Jan, O'Sullivan, Roderick J

“…Key Points Telomeric proteins control telomere length and telomere integrity. The six bona fide telomeric binding proteins form shelterin, a complex that…”
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Consumer Brand Engagement in Social Media: Conceptualization, Scale Development and Validation by Hollebeek, Linda D., Glynn, Mark S., Brodie, Roderick J.

“…In the last three decades, an influential research stream has emerged which highlights the dynamics of focal consumer/brand relationships. Specifically, more…”
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Papillary thyroid microcarcinoma: Is active surveillance always enough? by Sutherland, Rosie, Tsang, Venessa, Clifton‐Bligh, Roderick J., Gild, Matti L.

“…The incidence of papillary thyroid carcinoma (PTC) has increased over recent decades. This apparent epidemic has been attributed to the overdiagnosis of small…”
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Missing Data Analysis by Little, Roderick J

“…Methods for handling missing data in clinical psychology studies are reviewed. Missing data are defined, and a taxonomy of main approaches to analysis is…”
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Genome rearrangements associated with aberrant telomere maintenance by Bhargava, Ragini, Fischer, Matthias, O’Sullivan, Roderick J

“…There is unequivocal evidence that telomeres are crucial for cellular homeostasis and that telomere dysfunction can elicit genome instability and potentially…”
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Matrix metalloproteinases in kidney homeostasis and diseases by Tan, Roderick J, Liu, Youhua

“…Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have been increasingly linked to both normal physiology and abnormal…”
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Transdisciplinarity: Science for the public good by Lawrence, Roderick J.

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Actor engagement as a microfoundation for value co-creation by Storbacka, Kaj, Brodie, Roderick J., Böhmann, Tilo, Maglio, Paul P., Nenonen, Suvi

“…The starting point for this research is that value co-creation is difficult to observe empirically, whereas actor engagement is observable and thus more likely…”
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Actor Engagement in Networks: Defining the Conceptual Domain by Brodie, Roderick J., Fehrer, Julia A., Jaakkola, Elina, Conduit, Jodie

“…Considerable managerial and academic interest has made engagement a key priority in marketing and service research, spurring a rapidly increasing body of…”
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Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres by Karlseder, Jan, Kubicek, Stefan, Schreiber, Stuart L, O'Sullivan, Roderick J

“…Telomere shortening, senescence and aging are connected, but how the signal at shortening telomeres is transmitted to the cell more globally is unclear. H3 and…”
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Risk stratification of indeterminate thyroid nodules using ultrasound and machine learning algorithms by Gild, Matti Lauren, Chan, Mico, Gajera, Jay, Lurie, Brett, Gandomkar, Ziba, Clifton‐Bligh, Roderick J.

“…Background Indeterminate thyroid nodules (Bethesda III) are challenging to characterize without diagnostic surgery. Auxiliary strategies including molecular…”
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One small mouse step for man by Tan, Roderick J

“…The effect of spaceflight on kidney function requires additional study. The nuclear factor erythroid 2-related factor 2 knockout mouse became the first…”
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Myofibroblast in Kidney Fibrosis: Origin, Activation, and Regulation by Yuan, Qian, Tan, Roderick J, Liu, Youhua

“…Renal fibrosis is characterized by excessive deposition of extracellular matrix (ECM), leading to destruction of normal kidney architecture and loss of renal…”
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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1 by O'Sullivan, Roderick J, Arnoult, Nausica, Lackner, Daniel H, Oganesian, Liana, Haggblom, Candy, Corpet, Armelle, Almouzni, Genevieve, Karlseder, Jan

“…Some cancer cells lacking telomerase activity extend their telomeres via an alternative, recombination-based mechanism, termed ALT. A new study shows that…”
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Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword by Zhou, Dong, Tan, Roderick J, Fu, Haiyan, Liu, Youhua

“…The Wnt/β-catenin signaling cascade is an evolutionarily conserved, highly complex pathway that is known to be involved in kidney injury and repair after a…”
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Alternative Lengthening of Telomeres: Building Bridges To Connect Chromosome Ends by Hoang, Song My, O'Sullivan, Roderick J

“…Alternative lengthening of telomeres (ALT) is a mechanism of telomere maintenance that is observed in many of the most recalcitrant cancer subtypes. Telomeres…”
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Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production by Ghosh, Arundhati, Shao, Lulu, Sampath, Padmavathi, Zhao, Baoyu, Patel, Nidhi V., Zhu, Jianzhong, Behl, Bharat, Parise, Robert A., Beumer, Jan H., O’Sullivan, Roderick J., DeLuca, Neal A., Thorne, Stephen H., Rathinam, Vijay A.K., Li, Pingwei, Sarkar, Saumendra N.

“…Interferon-inducible human oligoadenylate synthetase-like (OASL) and its mouse ortholog, Oasl2, enhance RNA-sensor RIG-I-mediated type I interferon (IFN)…”
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Antifungal-resistant Trichophyton indotineae: transmission is occurring outside previously identified endemic areas - are we prepared? by Abdolrasouli, Alireza, Hay, Roderick J

“…This is a response to ‘Rapid emergence of recalcitrant dermatophytosis caused by a cluster of multidrug-resistant Trichophyton indotineae in China’ by Xie et…”
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Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling by Longarini, Edoardo José, Dauben, Helen, Locatelli, Carolina, Wondisford, Anne R., Smith, Rebecca, Muench, Charlotte, Kolvenbach, Andreas, Lynskey, Michelle Lee, Pope, Alexis, Bonfiglio, Juan José, Jurado, Eva Pinto, Fajka-Boja, Roberta, Colby, Thomas, Schuller, Marion, Ahel, Ivan, Timinszky, Gyula, O’Sullivan, Roderick J., Huet, Sébastien, Matic, Ivan

“…PARP1, an established anti-cancer target that regulates many cellular pathways, including DNA repair signaling, has been intensely studied for decades as a…”
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Sustained Activation of Wnt/β-Catenin Signaling Drives AKI to CKD Progression by Xiao, Liangxiang, Zhou, Dong, Tan, Roderick J, Fu, Haiyan, Zhou, Lili, Hou, Fan Fan, Liu, Youhua

“…AKI is increasingly recognized as a major risk factor for progression to CKD. However, the factors governing AKI to CKD progression are poorly understood. In…”
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