Search Results - "Rockstroh, Juergen"

Reinfection With the Hepatitis C Virus in Men Who Have Sex With Men After Successful Treatment With Direct-acting Antivirals in Germany: Current Incidence Rates, Compared With Rates During the Interferon Era by Ingiliz, Patrick, Wehmeyer, Malte H, Boesecke, Christoph, Schulze Zur Wiesch, Julian, Schewe, Knud, Lutz, Thomas, Baumgarten, Axel, Simon, Karl-Georg, Hueppe, Dietrich, Rockstroh, Juergen K, Mauss, Stefan, Christensen, Stefan

“…Abstract Background Micro-elimination of the hepatitis C virus (HCV) includes treatment in populations at risk of ongoing HCV transmission, such as men who…”
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Changes in weight and BMI with first-line doravirine-based therapy by Orkin, Chloe, Elion, Richard, Thompson, Melanie, Rockstroh, Juergen K., Alvarez Bognar, Fernando, Xu, Zhi J., Hwang, Carey, Sklar, Peter, Martin, Elizabeth A.

“…OBJECTIVE:To evaluate changes in weight and BMI in adults with HIV-1 at 1 and 2 years after starting an antiretroviral regimen that included doravirine,…”
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Durable Efficacy and Safety of Raltegravir Versus Efavirenz When Combined With Tenofovir/Emtricitabine in Treatment-Naive HIV-1–Infected Patients: Final 5-Year Results From STARTMRK by Rockstroh, Jürgen K, DeJesus, Edwin, Lennox, Jeffrey L, Yazdanpanah, Yazdan, Saag, Michael S, Wan, Hong, Rodgers, Anthony J, Walker, Monica L, Miller, Michael, DiNubile, Mark J, Nguyen, Bach-Yen, Teppler, Hedy, Leavitt, Randi, Sklar, Peter

“…BACKGROUND:STARTMRK, a phase III noninferiority trial of raltegravir-based versus efavirenz-based therapy in treatment-naive patients, remained blinded until…”
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The effect of weight gain and metabolic dysfunction-associated steatotic liver disease on liver fibrosis progression and regression in people with HIV by Guaraldi, Giovanni, Milic, Jovana, Renzetti, Stefano, Motta, Federico, Cinque, Felice, Bischoff, Jenny, Desilani, Andrea, Conti, Jacopo, Medioli, Filippo, Del Monte, Martina, Kablawi, Dana, Elgretli, Wesal, Calza, Stefano, Mussini, Cristina, Rockstroh, Juergen K, Sebastiani, Giada

“…People with HIV (PWH) have high risk of liver fibrosis. We investigated the effect of weight gain and metabolic dysfunction-associated steatotic liver disease…”
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Sofosbuvir plus ribavirin for treatment of hepatitis C virus in patients co-infected with HIV (PHOTON-2): a multicentre, open-label, non-randomised, phase 3 study by Molina, Jean-Michel, Prof, Orkin, Chloe, MD, Iser, David M, MBBS, Zamora, Francisco-Xavier, MD, Nelson, Mark, MBBS, Stephan, Christoph, Prof, Massetto, Benedetta, MD, Gaggar, Anuj, MD, Ni, Liyun, MA, Svarovskaia, Evguenia, PhD, Brainard, Diana, MD, Subramanian, G Mani, MD, McHutchison, John G, MD, Puoti, Massimo, Prof, Rockstroh, Jürgen K, Prof

“…Summary Background Although interferon-free regimens are approved for patients co-infected with HIV and genotype-2 or genotype-3 hepatitis C virus (HCV),…”
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Sofosbuvir and Ledipasvir for 8 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Infection in HCV-Monoinfected and HIV-HCV–Coinfected Individuals: Results From the German Hepatitis C Cohort (GECCO-01) by Ingiliz, Patrick, Christensen, Stefan, Kimhofer, Torben, Hueppe, Dietrich, Lutz, Thomas, Schewe, Knud, Busch, Heiner, Schmutz, Günther, Wehmeyer, Malte H., Boesecke, Christoph, Simon, Karl-Georg, Berger, Florian, Rockstroh, Jürgen K., zur Wiesch, Julian Schulze, Baumgarten, Axel, Mauss, Stefan

“…Background. Shortening the duration of treatment with HCV direct-acting antivirals (DAAs) leads to substantial cost reductions. According to the label,…”
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Torque Teno Virus Load Is Associated With Centers for Disease Control and Prevention Stage and CD4+ Cell Count in People Living With Human Immunodeficiency Virus but Seems Unrelated to AIDS-Defining Events and Human Pegivirus Load by Esser, Pia L, Quintanares, Gibran H Rubio, Langhans, Bettina, Heger, Eva, Böhm, Michael, Jensen, Björn-Erik O L E, Esser, Stefan, Lübke, Nadine, Fätkenheuer, Gerd, Lengauer, Thomas, Klein, Florian, Oette, Mark, Rockstroh, Juergen K, Boesecke, Christoph, Di Cristanziano, Veronica, Kaiser, Rolf, Pirkl, Martin

“…Abstract Background Torque teno virus (TTV) is part of the human virome. TTV load was related to the immune status in patients after organ transplantation. We…”
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Once daily dolutegravir (S/GSK1349572) in combination therapy in antiretroviral-naive adults with HIV: planned interim 48 week results from SPRING-1, a dose-ranging, randomised, phase 2b trial by van Lunzen, Jan, Prof, Maggiolo, Franco, MD, Arribas, José R, Prof, Rakhmanova, Aza, MD, Yeni, Patrick, Prof, Young, Benjamin, MD, Rockstroh, Jürgen K, Prof, Almond, Steve, MMath, Song, Ivy, PhD, Brothers, Cindy, MSPH, Min, Sherene, MD

“…Summary Background Dolutegravir (S/GSK1349572) is a new HIV-1 integrase inhibitor that has antiviral activity with once daily, unboosted dosing. SPRING-1 is an…”
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HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1 by Altfeld, Marcus, Kalife, Elizabeth T, Qi, Ying, Streeck, Hendrik, Lichterfeld, Mathias, Johnston, Mary N, Burgett, Nicole, Swartz, Martha E, Yang, Amy, Alter, Galit, Yu, Xu G, Meier, Angela, Rockstroh, Juergen K, Allen, Todd M, Jessen, Heiko, Rosenberg, Eric S, Carrington, Mary, Walker, Bruce D

“…Very little is known about the immunodominance patterns of HIV-1-specific T cell responses during primary HIV-1 infection and the reasons for human lymphocyte…”
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HIV-related stigma within communities of gay men: a literature review by Smit, Peter J., Brady, Michael, Carter, Michael, Fernandes, Ricardo, Lamore, Lance, Meulbroek, Michael, Ohayon, Michel, Platteau, Tom, Rehberg, Peter, Rockstroh, Jürgen K., Thompson, Marc

“…While stigma associated with HIV infection is well recognised, there is limited information on the impact of HIV-related stigma between men who have sex with…”
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A Randomized, Double-Blind Comparison of Coformulated Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF vs Ritonavir-Boosted Atazanavir Plus Coformulated Emtricitabine and Tenofovir DF for Initial Treatment of HIV-1 Infection: Analysis of Week 96 Results by ROCKSTROH, Jürgen K, DEJESUS, Edwin, FORDYCE, Marshall W, SZWARCBERG, Javier, HENRY, Keith, MOLINA, Jean-Michel, GATHE, Joseph, RAMANATHAN, Srinivasan, XUELIAN WEI, PLUMMER, Andrew, ABRAM, Michael, CHENG, Andrew K

“…This ongoing, randomized, double-blind, active-controlled phase 3 international trial demonstrated the noninferior efficacy of…”
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Effect of antiviral therapy for HCV on lipid levels by Mauss, Stefan, Berger, Florian, Wehmeyer, Malte H, Ingiliz, Patrick, Hueppe, Dietrich, Lutz, Thomas, Simon, Karl G, Schewe, Knud, Rockstroh, Juergen K, Baumgarten, Axel, Christensen, Stefan

“…HCV has complex interactions with human lipid metabolism leading to down regulation of cholesterol levels. Interferon (IFN) therapy has been shown to decrease…”
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Trouble with bleeding: risk factors for acute hepatitis C among HIV-positive gay men from Germany--a case-control study by Schmidt, Axel J, Rockstroh, Jürgen K, Vogel, Martin, An der Heiden, Matthias, Baillot, Armin, Krznaric, Ivanka, Radun, Doris

“…To identify risk factors for hepatitis C among HIV-positive men who have sex with men (MSM), focusing on potential sexual, nosocomial, and other non-sexual…”
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High Sustained Virologic Response Rates of Glecaprevir/Pibrentasvir in Patients With Dosing Interruption or Suboptimal Adherence by Zamor, Philippe J., Brown, Ashley, Dylla, Douglas E., Dillon, John F., Luetkemeyer, Anne F., Feld, Jordan J., Mutimer, David, Ghalib, Reem, Crown, Eric, Lovell, Sandra S., Hu, Yiran, Moreno, Christophe, Nelson, David R., Colombo, Massimo, Papatheodoridis, Georgios, Rockstroh, Juergen K., Skoien, Richard, Lawitz, Eric, Jacobson, Ira M.

“…Pangenotypic, all-oral direct-acting antivirals, such as glecaprevir/pibrentasvir (G/P), are recommended for treatment of hepatitis C virus (HCV) infection…”
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Benefit of Early versus Deferred Antiretroviral Therapy on Progression of Liver Fibrosis among People with HIV in the START Randomized Trial by Dharan, Nila J., Neuhaus, Jacqueline, Rockstroh, Juergen K., Peters, Lars, Gordin, Fred, Arenas‐Pinto, Alejandro, Emerson, Carol, Marks, Kristen, Hidalgo, Jose, Sarmento‐Castro, Rui, Stephan, Christoph, Kumarasamy, Nagalingeswaran, Emery, Sean, Matthews, Gail V.

“…The role of antiretroviral therapy (ART) in reducing or contributing to liver fibrosis in persons with human immunodeficiency virus (HIV) is unclear. We…”
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Trends in Incidences and Risk Factors for Hepatocellular Carcinoma and Other Liver Events in HIV and Hepatitis C Virus-coinfected Individuals From 2001 to 2014: A Multicohort Study by Gjærde, Lars I., Shepherd, Leah, Jablonowska, Elzbieta, Lazzarin, Adriano, Rougemont, Mathieu, Darling, Katharine, Battegay, Manuel, Braun, Dominique, Martel-Laferriere, Valerie, Lundgren, Jens D., Rockstroh, Jürgen K., Gill, John, Rauch, Andri, Mocroft, Amanda, Klein, Marina B., Peters, Lars

“…Background. While liver-related deaths in human immunodeficiency virus (HIV) and hepatitis C virus (HCV)-coinfected individuals have declined over the last…”
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Antiretroviral drugs and liver injury by SORIANO, Vincent, PUOTI, Massimo, GARCIA-GASCO, Pilar, ROCKSTROH, Juergen K, BENHAMOU, Yves, BARREIRO, Pablo, MCGOVERN, Barbara

“…Antiretroviral drug-related liver injury (ARLI) is a common cause of morbidity, mortality and treatment discontinuation in HIV-infected patients. Prevention…”
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Boceprevir or Telaprevir Based Triple Therapy against Chronic Hepatitis C in HIV Coinfection: Real-Life Safety and Efficacy by Neukam, Karin, Munteanu, Daniela I, Rivero-Juárez, Antonio, Lutz, Thomas, Fehr, Jan, Mandorfer, Mattias, Bhagani, Sanjay, López-Cortés, Luis F, Haberl, Annette, Stoeckle, Marcel, Márquez, Manuel, Scholten, Stefan, de Los Santos-Gil, Ignacio, Mauss, Stefan, Rivero, Antonio, Collado, Antonio, Delgado, Marcial, Rockstroh, Juergen K, Pineda, Juan A

“…Clinical trials of therapy against chronic hepatitis C virus (HCV) infection including boceprevir (BOC) or telaprevir (TVR) plus pegylated interferon and…”
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Raltegravir once daily or twice daily in previously untreated patients with HIV-1: a randomised, active-controlled, phase 3 non-inferiority trial by Eron, Joseph J, Prof, Rockstroh, Jürgen K, MD, Reynes, Jacques, Prof, Andrade-Villanueva, Jaime, MD, Ramalho-Madruga, Jose Valdez, MD, Bekker, Linda-Gail, MD, Young, Benjamin, MD, Katlama, Christine, MD, Gatell-Artigas, Jose Maria, MD, Arribas, Jose R, MD, Nelson, Mark, MD, Campbell, Havilland, BS, Zhao, Jing, PhD, Rodgers, Anthony J, MS, Rizk, Matthew L, PhD, Wenning, Larissa, PhD, Miller, Michael D, PhD, Hazuda, Daria, PhD, DiNubile, Mark J, MD, Leavitt, Randi, MD, Isaacs, Robin, MD, Robertson, Michael N, MD, Sklar, Peter, MD, Nguyen, Bach-Yen, Dr

“…Summary Background Twice-daily raltegravir with once-daily tenofovir-emtricitabine is an effective initial antiretroviral regimen for patients with HIV-1. On…”
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Real‐world effectiveness of sofosbuvir‐based treatment regimens for chronic hepatitis C genotype 3 infection: Results from the multicenter German hepatitis C cohort (GECCO‐03) by Wehmeyer, Malte H., Ingiliz, Patrick, Christensen, Stefan, Hueppe, Dietrich, Lutz, Thomas, Simon, Karl Georg, Schewe, Knud, Boesecke, Christoph, Baumgarten, Axel, Busch, Heiner, Rockstroh, Juergen, Schmutz, Guenther, Kimhofer, Torben, Berger, Florian, Mauss, Stefan, Schulze zur Wiesch, Julian

“…There are limited data regarding the real world effectiveness of direct acting antivirals (DAA) for the therapy of chronic genotype 3 hepatitis C virus (HCV)…”
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