Search Results - "Rockett, John C."

Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs by Platts, Adrian E., Dix, David J., Chemes, Hector E., Thompson, Kary E., Goodrich, Robert, Rockett, John C., Rawe, Vanesa Y., Quintana, Silvina, Diamond, Michael P., Strader, Lillian F., Krawetz, Stephen A.

“…We are coming to appreciate that at fertilization human spermatozoa deliver the paternal genome alongside a suite of structures, proteins and RNAs. Although…”
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Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides by Tully, Douglas B., Bao, Wenjun, Goetz, Amber K., Blystone, Chad R., Ren, Hongzu, Schmid, Judith E., Strader, Lillian F., Wood, Carmen R., Best, Deborah S., Narotsky, Michael G., Wolf, Douglas C., Rockett, John C., Dix, David J.

“…Four triazole fungicides were studied using toxicogenomic techniques to identify potential mechanisms of action. Adult male Sprague-Dawley rats were dosed for…”
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Overview of an Interlaboratory Collaboration on Evaluating the Effects of Model Hepatotoxicants on Hepatic Gene Expression by Ulrich, Roger G., Rockett, John C., Gibson, G. Gordon, Pettit, Syril D.

“…DNA microarrays and related tools offer promise for identification of pathways involved in toxic responses to xenobiotics. To be useful for risk assessment,…”
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Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides by Goetz, Amber K., Bao, Wenjun, Ren, Hongzu, Schmid, Judith E., Tully, Douglas B., Wood, Carmen, Rockett, John C., Narotsky, Michael G., Sun, Guobin, Lambert, Guy R., Thai, Sheau-Fung, Wolf, Douglas C., Nesnow, Stephen, Dix, David J.

“…Four triazole fungicides used in agricultural or pharmaceutical applications were examined for hepatotoxic effects in mouse liver. Besides organ weight,…”
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Clofibrate-Induced Gene Expression Changes in Rat Liver: A Cross-Laboratory Analysis Using Membrane cDNA Arrays by Baker, Valerie A., Harries, Helen M., Waring, Jeff F., Duggan, Colette M., Ni, Hong A., Jolly, Robert A., Yoon, Lawrence W., De Souza, Angus T., Schmid, Judith E., Brown, Roger H., Ulrich, Roger G., Rockett, John C.

“…Microarrays have the potential to significantly impact our ability to identify toxic hazards by the identification of mechanistically relevant markers of…”
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Disruption of Testosterone Homeostasis as a Mode of Action for the Reproductive Toxicity of Triazole Fungicides in the Male Rat by Goetz, Amber K., Ren, Hongzu, Schmid, Judith E., Blystone, Chad R., Thillainadarajah, Inthirany, Best, Deborah S., Nichols, Harriette P., Strader, Lillian F., Wolf, Douglas C., Narotsky, Michael G., Rockett, John C., Dix, David J.

“…Triazole fungicides associated with a range of reported male reproductive effects in experimental animals were selected to assess potential toxic modes of…”
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Confirming microarray data—is it really necessary? by Rockett, John C, Hellmann, Gary M

“…The generation of corroborative data has become a commonly used approach for ensuring the veracity of microarray data. Indeed, the need to conduct…”
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Effects of Hyperthermia on Spermatogenesis, Apoptosis, Gene Expression, and Fertility in Adult Male Mice by ROCKETT, John C, MAPP, Faye L, GARGES, J. Brian, LUFT, J. Christopher, MORI, Chisato, DIX, David J

“…Testicular heat shock was used to characterize cellular and molecular mechanisms involved in male fertility. This model is relevant because heat shock proteins…”
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Biomarkers for Assessing Reproductive Development and Health: Part 1: Pubertal Development by Rockett, John C., Lynch, Courtney D., Buck, Germaine M.

“…The proposed National Children's Study has helped raise awareness of the issues related to children's health and the importance of monitoring the growth and…”
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Effects of Storage, RNA Extraction, Genechip Type, and Donor Sex on Gene Expression Profiling of Human Whole Blood by Kim, Sung Jae, Dix, David J, Thompson, Kary E, Murrell, Rachel N, Schmid, Judith E, Gallagher, Jane E, Rockett, John C

“…Gene expression profiling of whole blood may be useful for monitoring toxicological exposure and for diagnosis and monitoring of various diseases. Several…”
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Inhibition of Rat and Human Steroidogenesis by Triazole Antifungals by Goetz, Amber K., Rockett, John C., Ren, Hongzu, Thillainadarajah, Inthirany, Dix, David J.

“…Environmental chemicals that alter steroid production could interfere with male reproductive development and function. Three agricultural antifungal triazoles…”
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Biomarkers of ovulation, endometrial receptivity, fertilisation, implantation and early pregnancy progression by Campbell, Kenneth L., Rockett, John C.

“…Summary Increasing interest in early preconception and periconception exposures and human developmental outcomes has led to studies that monitor subjects from…”
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The Value of Home-Based Collection of Biospecimens in Reproductive Epidemiology by Rockett, John C., Buck, Germaine M., Lynch, Courtney D., Perreault, Sally D.

“…Detection, quantification, and prognosis of environmental exposures in humans has been vastly enhanced by the ability of epidemiologists to collect…”
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Prospective Pregnancy Study Designs for Assessing Reproductive and Developmental Toxicants by Buck, Germaine M., Lynch, Courtney D., Stanford, Joseph B., Sweeney, Anne M., Schieve, Laura A., Rockett, John C., Selevan, Sherry G., Schrader, Steven M.

“…The determinants of successful human reproduction and development may act as early as periconceptionally, underscoring the need to capture exposures during…”
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Effect of conazole fungicides on reproductive development in the female rat by Rockett, John C., Narotsky, Michael G., Thompson, Kary E., Thillainadarajah, Inthirany, Blystone, Chad R., Goetz, Amber K., Ren, Hongzu, Best, Deborah S., Murrell, Rachel N., Nichols, Harriette P., Schmid, Judith E., Wolf, Douglas C., Dix, David J.

“…Three triazole fungicides were evaluated for effects on female rat reproductive development. Rats were exposed via feed to propiconazole (P) (100, 500, or 2500…”
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Surrogate tissue analysis: monitoring toxicant exposure and health status of inaccessible tissues through the analysis of accessible tissues and cells by Rockett, John C, Burczynski, Michael E, Fornace, Albert J, Herrmann, Paul C, Krawetz, Stephen A, Dix, David J

“…Genomics and proteomics have made it possible to define molecular physiology in exquisite detail, when tissues are accessible for sampling. However, many…”
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Effects of Hyperthermia on Spermatogenesis, Apoptosis, Gene Expression, and Fertility in Adult Male Mice1 by Rockett, John C, Mapp, Faye L, Garges, J. Brian, Luft, J. Christopher, Mori, Chisato, Dix, David J

“…Testicular heat shock was used to characterize cellular and molecular mechanisms involved in male fertility. This model is relevant because heat shock proteins…”
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Chip, chip, array! Three chips for post-genomic research by Rockett, John C

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Sid knocks them out by Rockett, John C

“…A putative transmembrane protein is required for systemic RNAi in Caenorhabditis elegans…”
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Macroresults through Microarrays by Rockett, John C

“…The third enactment of Cambridge Healthtech Institute's Macroresults through Microarrays meeting was held in Boston (MA, USA) from 29 April–1 May 2002. The…”
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