Search Results - "Rockenbach, Liliana"
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P2Y12 Purinergic Receptor and Brain Tumors: Implications on Glioma Microenvironment
Published in Molecules (Basel, Switzerland) (12-10-2021)“…Gliomas are the most common malignant brain tumors in adults, characterized by a high proliferation and invasion. The tumor microenvironment is rich in…”
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The functional role of p38 MAPK pathway in malignant brain tumors
Published in Frontiers in pharmacology (03-10-2022)“…Gliomas are extremely debilitating malignant brain tumors with very limited response to therapies. The initiation and progression of gliomas can be attributed…”
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The potential role of purinergic signaling in cancer therapy: perspectives on anti-CD73 strategies for prostate cancer
Published in Frontiers in immunology (17-09-2024)“…Purines and pyrimidines are signaling molecules in the tumor microenvironment that affect cancer immunity. The purinergic signaling pathways have been shown to…”
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Immunosuppression in Gliomas via PD-1/PD-L1 Axis and Adenosine Pathway
Published in Frontiers in oncology (15-02-2021)“…Glioblastoma is the most malignant and lethal subtype of glioma. Despite progress in therapeutic approaches, issues with the tumor immune landscape persist…”
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AMP hydrolysis reduction in blood plasma of breast cancer elderly patients after different treatments
Published in Molecular and cellular biochemistry (01-10-2021)“…Adenine nucleotides are important signaling molecules that mediate biological functions in many conditions, including cancer. The enzymes CD39 and CD73 produce…”
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Exploring CD39 and CD73 Expression as Potential Biomarkers in Prostate Cancer
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2023)“…Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73…”
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P2Y12 receptor antagonism inhibits proliferation, migration and leads to autophagy of glioblastoma cells
Published in Purinergic signalling (01-12-2022)“…Glioblastoma (GBM) is the most aggressive and lethal among the primary brain tumors, with a low survival rate and resistance to radio and chemotherapy. The P2Y…”
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Characterization of Ectonucleotidases in Human Medulloblastoma Cell Lines: ecto-5′NT/CD73 in Metastasis as Potential Prognostic Factor
Published in PloS one (18-10-2012)“…Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules,…”
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The Quinovic Acid Glycosides Purified Fraction from Uncaria tomentosa Protects against Hemorrhagic Cystitis Induced by Cyclophosphamide in Mice
Published in PloS one (08-07-2015)“…Uncaria tomentosa is widely used in folk medicine for the treatment of numerous diseases, such as urinary tract disease. Hemorrhagic cystitis (HE) is an…”
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Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells
Published in Urologic oncology (01-10-2013)“…Abstract Bladder cancer is the most prevalent tumor in the genitourinary tract and the current treatments are not efficient to prevent recurrence and…”
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Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells
Published in Mediators of Inflammation (01-01-2014)“…Interleukin-8 (IL-8) plays key roles in both chronic inflammatory diseases and tumor modulation. We previously observed that IL-8 secretion and function can be…”
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Ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Published in MolBank (01-12-2018)“…The Biginelli reaction is a highly versatile reaction that leads to dihydropyrimidinones/thiones. This scaffold is reported as being a privileged structure due…”
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Correction: Characterization of Ectonucleotidases in Human Medulloblastoma Cell Lines: ecto-5′NT/CD73 in Metastasis as Potential Prognostic Factor
Published in PloS one (06-11-2012)“…The final author's name was spelled incorrectly. (2012) Correction: Characterization of Ectonucleotidases in Human Medulloblastoma Cell Lines: ecto-5′NT/CD73…”
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14
Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor
Published in PloS one (18-10-2012)“…Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules,…”
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15
Anticonvulsant Role of Adenosine is Blunted During Alcohol Withdrawal Syndrome in an Adult Zebrafish Model
Published in Neurochemical research (01-10-2023)“…Alcohol (ethanol) dependence and related disorders are life-threatening conditions and source of suffering for the user, family members and society. Alcohol…”
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Inhibition of ATP hydrolysis as a key regulator of temozolomide resistance and migratory phenotype of glioblastoma cells
Published in Biochemical and biophysical research communications (23-04-2022)“…Glioblastoma (GBM) is the most lethal among malignant gliomas. The tumor invasiveness and therapy-resistance are important clinical hallmarks. Growing evidence…”
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17
P2Y 12 Purinergic Receptor and Brain Tumors: Implications on Glioma Microenvironment
Published in Molecules (Basel, Switzerland) (12-10-2021)“…Gliomas are the most common malignant brain tumors in adults, characterized by a high proliferation and invasion. The tumor microenvironment is rich in…”
Get full text
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18
Versatility of the Biginelli reaction: Synthesis of new biphenyl dihydropyrimidin-2-thiones using different ketones as building blocks
Published in Tetrahedron letters (11-07-2018)“…[Display omitted] •Biphenyl dihydropyrimidin-2-thiones were synthesized via Biginelli reaction.•The synthesis was performed using simple ketones and di-ketones…”
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Altered extracellular ATP, ADP, and AMP hydrolysis in blood serum of sedentary individuals after an acute, aerobic, moderate exercise session
Published in Molecular and cellular biochemistry (01-02-2017)“…Nucleotidases participate in the regulation of physiological and pathological events, such as inflammation and coagulation. Exercise promotes distinct…”
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Ecto-5′-nucleotidase/CD73 contributes to the radiosensitivity of T24 human bladder cancer cell line
Published in Journal of cancer research and clinical oncology (01-03-2018)“…Purpose Trimodal therapy is a reasonable bladder-preserving option to radical cystectomy. However, many tumors are radioresistive. In this sense, the…”
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