Search Results - "Rockel, Thomas D"

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense by Moschos, Sterghios A, Frick, Manfred, Taylor, Bruce, Turnpenny, Paul, Graves, Helen, Spink, Karen G, Brady, Kevin, Lamb, David, Collins, David, Rockel, Thomas D, Weber, Markus, Lazari, Ovadia, Perez-Tosar, Luis, Fancy, Sally A, Lapthorn, Chris, Green, Martin X, Evans, Steve, Selby, Matthew, Jones, Gareth, Jones, Lyn, Kearney, Sarah, Mechiche, Houria, Gikunju, Diana, Subramanian, Romesh, Uhlmann, Eugen, Jurk, Marion, Vollmer, Jörg, Ciaramella, Giuseppe, Yeadon, Michael

“…Antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) promise specific correction of disease-causing gene expression. Therapeutic implementation,…”
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Anti‐ACSA‐2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes by Kantzer, Christina G., Boutin, Camille, Herzig, Ina D., Wittwer, Carolina, Reiß, Sandy, Tiveron, Marie Catherine, Drewes, Jan, Rockel, Thomas D., Ohlig, Stefanie, Ninkovic, Jovica, Cremer, Harold, Pennartz, Sandra, Jungblut, Melanie, Bosio, Andreas

“…Astrocytes are the most abundant cell type of the central nervous system and cover a broad range of functionalities. We report here the generation of a novel…”
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Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers by Subramanian, Romesh R, Wysk, Mark A, Ogilvie, Kathleen M, Bhat, Abhijit, Kuang, Bing, Rockel, Thomas D, Weber, Markus, Uhlmann, Eugen, Krieg, Arthur M

“…The in vivo potency of antisense oligonucleotides (ASO) has been significantly increased by reducing their length to 8-15 nucleotides and by the incorporation…”
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Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing by Moors, Michaela, Rockel, Thomas Dino, Abel, Josef, Cline, Jason E., Gassmann, Kathrin, Schreiber, Timm, Schuwald, Janette, Weinmann, Nicole, Fritsche, Ellen

“…Background: Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose…”
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Anti-ACSA-2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes: Kantzer et al by Kantzer, Christina G., Boutin, Camille, Herzig, Ina D., Wittwer, Carolina, Reiß, Sandy, Tiveron, Marie Catherine, Drewes, Jan, Rockel, Thomas D., Ohlig, Stefanie, Ninkovic, Jovica, Cremer, Harold, Pennartz, Sandra, Jungblut, Melanie, Bosio, Andreas

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