Search Results - "Rock, D.L."

Mutations in the carboxyl terminal region of E2 glycoprotein of classical swine fever virus are responsible for viral attenuation in swine by Risatti, G.R, Holinka, L.G, Fernandez Sainz, I, Carrillo, C, Kutish, G.F, Lu, Z, Zhu, J, Rock, D.L, Borca, M.V

“…Abstract We have previously reported [Risatti, G.R., Borca, M.V., Kutish, G.F., Lu, Z., Holinka, L.G., French, R.A., Tulman, E.R., Rock, D.L. 2005a. The E2…”
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Mutation of E1 glycoprotein of classical swine fever virus affects viral virulence in swine by Risatti, G.R., Holinka, L.G., Lu, Z., Kutish, G.F., Tulman, E.R., French, R.A., Sur, J.H., Rock, D.L., Borca, M.V.

“…Transposon linker insertion mutagenesis of a full-length infectious clone (IC) (pBIC) of the pathogenic classical swine fever virus (CSFV) strain Brescia was…”
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Virological and clinico-pathological features of orf virus infection in experimentally infected rabbits and mice by Cargnelutti, J.F., Masuda, E.K., Martins, M., Diel, D.G., Rock, D.L., Weiblen, R., Flores, E.F.

“…Many aspects of the biology of orf virus (ORFV) infection remain poorly understood and attempts to establish animal models have yielded conflicting and…”
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Challenges for African swine fever vaccine development—“… perhaps the end of the beginning.” by Rock, D.L.

“…•There is no vaccine available for ASF, thus leaving animal slaughter the only effective disease control option.•Vaccine development has been hindered by large…”
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Passively transferred African swine fever virus antibodies protect swine against lethal infection by Onisk, D V, Borca, M V, Kutish, G, Kramer, E, Irusta, P, Rock, D L

“…The role of anti-viral antibodies in homologous protective immunity to a virulent African swine fever virus (ASFV) strain E75 was examined by passive transfer…”
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Amino Acid Tandem Repeats within a Late Viral Gene Define the Central Variable Region of African Swine Fever Virus by IRUSTA, P.M., BORCA, M.V., KUTISH, G.F., LU, Z., CALER, E., CARRILLO, C., ROCK, D.L.

“…The central variable region (CVR) of the African swine fever virus (ASFV) genome is contained within the 9-RL open reading frame (ORF). ORF 9-RL of the ASFV…”
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An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption by Borca, M V, Kutish, G F, Afonso, C L, Irusta, P, Carrillo, C, Brun, A, Sussman, M, Rock, D L

“…An open reading frame, LMW8-DR, in the African swine fever virus (ASFV) genome possesses striking similarity to the lymphocyte membrane antigen CD2. All…”
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African swine fever virus structural protein p72 contains a conformational neutralizing epitope by Borca, M V, Irusta, P, Carrillo, C, Afonso, C L, Burrage, T, Rock, D L

“…We have previously described a monoclonal antibody (mAb 135D4) to an unidentified 70- to 72-kDa African swine fever virus (ASFV) protein that exhibited high…”
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Comparative Genomics of Foot-and-Mouth Disease Virus by Carrillo, C, Tulman, E.R, Delhon, G, Lu, Z, Carreno, A, Vagnozzi, A, Kutish, G.F, Rock, D.L

“…Here we present complete genome sequences, including a comparative analysis, of 103 isolates of foot-andmouth disease virus (FMDV) representing all seven…”
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Two novel multigene families, 530 and 300, in the terminal variable regions of African swine fever virus genome by Yozawa, T, Kutish, G F, Afonso, C L, Lu, Z, Rock, D L

“…Here, we describe two novel multigene families (MGF) present in the terminal variable regions of the African swine fever virus (ASFV) genome. MGF530 includes…”
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African Swine Fever Virus (Asfv) Multigene Families 360 and 530 Genes Promote Infected Macrophage Survival by Zsak, L, Sur, J H, Burrage, T G, Neilan, J G, Rock, D L

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Neutralizing antibodies to African swine fever virus proteins p30, p54, and p72 are not sufficient for antibody-mediated protection by Neilan, J.G, Zsak, L, Lu, Z, Burrage, T.G, Kutish, G.F, Rock, D.L

“…Although antibody-mediated immune mechanisms have been shown to be important in immunity to ASF, it remains unclear what role virus neutralizing antibodies…”
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Genomes of the Parapoxviruses Orf Virus and Bovine Papular Stomatitis Virus by Delhon, G, Tulman, E.R, Afonso, C.L, Lu, Z, de la Concha-Bermejillo, A, Lehmkuhl, H.D, Piccone, M.E, Kutish, G.F, Rock, D.L

“…Bovine papular stomatitis virus (BPSV) and orf virus (ORFV), members of the genus Parapoxvirus of the Poxviridae, are etiologic agents of worldwide diseases…”
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Rapid Preclinical Detection of Sheeppox Virus by a Real-Time PCR Assay by Balinsky, C.A, Delhon, G, Smoliga, G, Prarat, M, French, R.A, Geary, S.J, Rock, D.L, Rodriguez, L.L

“…Sheeppox virus (SPPV) is a member of the Capripoxvirus (CaPV) genus of the Poxviridae family. Members of this genus, which also include goatpox and lumpy skin…”
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A BIR Motif Containing Gene of African Swine Fever Virus,4CL,Is Nonessential for Growthin Vitroand Viral Virulence by Neilan, J.G., Lu, Z., Kutish, G.F., Zsak, L., Burrage, T.G., Borca, M.V., Carrillo, C., Rock, D.L.

“…An African swine fever virus (ASFV) gene with similarity to viral and cellular inhibitor of apoptosis genes (iap) has been described in the African isolate…”
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Genome of Horsepox Virus by Tulman, E.R, Delhon, G, Afonso, C.L, Lu, Z, Zsak, L, Sandybaev, N.T, Kerembekova, U.Z, Zaitsev, V.L, Kutish, G.F, Rock, D.L

“…Here we present the genomic sequence of horsepox virus (HSPV) isolate MNR-76, an orthopoxvirus (OPV) isolated in 1976 from diseased Mongolian horses. The…”
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Genome of Canarypox Virus by Tulman, E.R, Afonso, C.L, Lu, Z, Zsak, L, Kutish, G.F, Rock, D.L

“…Here we present the genomic sequence, with analysis, of a canarypox virus (CNPV). The 365-kbp CNPV genome contains 328 potential genes in a central region and…”
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Genetic and Phenotypic Variation of Foot-and-Mouth Disease Virus during Serial Passages in a Natural Host by Carrillo, C, Lu, Z, Borca, M.V, Vagnozzi, A, Kutish, G.F, Rock, D.L

“…Foot-and-mouth disease virus (FMDV), like other RNA viruses, exhibits high mutation rates during replication that have been suggested to be of adaptive value…”
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E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine by Risatti, G.R, Borca, M.V, Kutish, G.F, Lu, Z, Holinka, L.G, French, R.A, Tulman, E.R, Rock, D.L

“…To identify genetic determinants of classical swine fever virus (CSFV) virulence and host range, chimeras of the highly pathogenic Brescia strain and the…”
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Detection of latent pseudorabies virus in swine using in situ hybridization by Brown, T M, Osorio, F A, Rock, D L

“…We have examined methods for detection of pseudorabies virus (PRV) latency in three groups of swine; naturally infected animals obtained from a field case;…”
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