Search Results - "Roche, Nanette S."

Incisional wound healing in transforming growth factor-β1 null mice by Koch, R. Michael, Roche, Nanette S, Parks, W. Tony, Ashcroft, Gillian S, Letterio, John J, Roberts, Anita B

“…Expression of endogenous transforming growth factor‐β1 is reduced in many animal models of impaired wound healing, and addition of exogenous transforming…”
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A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity by NANJOO SUH, YONGPING WANG, WILLIAMS, C. R, GENGFEI WU, DANNENBERG, A. J, FLANDERS, K. C, LETTERIO, J. J, MANGELSDORF, D. J, NATHAN, C. F, LANANH NGUYEN, PORTER, W. W, REN, R. F, HONDA, T, ROBERTS, A. B, ROCHE, N. S, SUBBARAMAIAH, K, SPORN, M. B, GRIBBLE, G. W, DMITROVSKY, E, HICKEY, W. F, MAUE, R. A, PLACE, A. E, PORTER, D. M, SPINELLA, M. J

“…The new synthetic oleanane triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) is a potent, multifunctional molecule. It induces monocytic…”
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Maternal rescue of transforming growth factor-beta 1 null mice by Letterio, J J, Geiser, A G, Kulkarni, A B, Roche, N S, Sporn, M B, Roberts, A B

“…Maternal sources of transforming growth factor-beta 1 (TGF-beta 1) are shown here to contribute to the normal appearance and perinatal survival of TGF-beta 1…”
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Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components by Vukicevic, S, Kleinman, H K, Luyten, F P, Roberts, A B, Roche, N S, Reddi, A H

“…We have recently demonstrated the formation of interconnecting canalicular cell processes in bone cells upon contact with basement membrane components. Here we…”
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Effects of steroids and retinoids on wound healing by Wicke, C, Halliday, B, Allen, D, Roche, N S, Scheuenstuhl, H, Spencer, M M, Roberts, A B, Hunt, T K

“…Anti-inflammatory corticosteroids significantly impair wound healing. Retinoids partially, but significantly, reverse this effect. Little is known about the…”
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Maternal Rescue of Transforming Growth Factor-β1 Null Mice by Letterio, John J., Geiser, Andrew G., Kulkarni, Ashok B., Roche, Nanette S., Sporn, Michael B., Roberts, Anita B.

“…Maternal sources of transforming growth factor-β1 (TGF-β1) are shown here to contribute to the normal appearance and perinatal survival of TGF-β1 null newborn…”
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Selective inhibition of the anchorage-independent growth of myc -transfected fibroblasts by retinoic acid by Roberts, Anita B, Roche, Nanette S, Sporn, Michael B

“…Fischer rat 3T3 (FR3T3) fibroblasts transfected with a cellular myc gene can be induced to grow and form colonies in soft agar by treatment either with…”
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Inhibition of Skin Development by Overexpression of Transforming Growth Factor β1in the Epidermis of Transgenic Mice by Sellheyer, Klaus, Bickenbach, Jackie R., Rothnagel, Joseph A., Bundman, Donnie, Longley, Mary Ann, Krieg, Thomas, Roche, Nanette S., Roberts, Anita B., Roop, Dennis R.

“…To assess the effect of transforming growth factor β1on the skin in vivo, we have targeted its expression to the epidermis of transgenic mice. To ensure that…”
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Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes by Roberts, A B, Vodovotz, Y, Roche, N S, Sporn, M B, Nathan, C F

“…We have recently shown that transforming growth factor-beta (TGF beta) acts in an autocrine manner to maintain the beating rate of neonatal rat cardiac…”
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A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta by Rossi, P, Karsenty, G, Roberts, A B, Roche, N S, Sporn, M B, de Crombrugghe, B

“…Transforming growth factor-beta (TGF-beta) increases the steady-state RNA levels of several fibroblast extracellular matrix proteins. Using DNA transfection,…”
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Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro by Roberts, A.B, Sporn, M.B, Assoian, R.K, Smith, J.M, Roche, N.S, Wakefield, L.M, Heine, U.I, Liotta, L.A, Falanga, V, Kehrl, J.H

“…Transforming growth factor type β (TGF-β ), when injected subcutaneously in newborn mice, causes formation of granulation tissue (induction of angiogenesis and…”
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Type β Transforming Growth Factor: A Bifunctional Regulator of Cellular Growth by Roberts, Anita B., Anzano, Mario A., Wakefield, Lalage M., Roche, Nanette S., Stern, David F., Sporn, Michael B.

“…Type β transforming growth factor (TGF-β ) is a two-chain polypeptide of 25,000 daltons isolated from many tissues, including bovine kidney, human placenta,…”
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Osteoblasts Synthesize and Respond to Transforming Growth Factor-Type β (TGF-β) in vitro by Robey, Pamela Gehron, Young, Marian F., Flanders, Kathleen C., Roche, Nanette S., Kondaiah, Paturu, Reddi, A. Hari, Termine, John D., Sporn, Michael B., Roberts, Anita B.

“…Transforming growth factor-type β (TGF-β) has been identified as a constituent of bone matrix (Seyedin, S. M., A. Y. Thompson, H. Bentz, D. M. Rosen, J. M…”
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Role of transforming growth factor-β in maintenance of function of cultured neonatal cardiac myocytes : autocrine action and reversal of damaging effects of interleukin-1 by ROBERTS, A B, ROCHE, N. S, WINOKUR, T. S, BURMESTER, J. K, SPORN, M. B

“…The three isoforms of transforming growth factor-beta (TGF-beta) have previously been implicated in embryonic development of the heart as well as in repair of…”
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Accumulation, Localization, and Compartmentation of Transforming Growth Factor β during Endochondral Bone Development by Carrington, Jill L., Roberts, Anita B., Flanders, Kathleen C., Roche, Nanette S., Reddi, A. Hari

“…Endochondral bone formation was induced in postnatal rats by implantation of demineralized rat bone matrix. Corresponding control tissue was generated by…”
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Mechanism of action of retinoids by Sporn, M B, Roberts, A B, Roche, N S, Kagechika, H, Shudo, K

“…In several recent reviews, we have suggested that the mechanism of action of retinoids in controlling cell differentiation is related to their effects on the…”
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Mesoderm induction in Xenopus laevis distinguishes between the various TGF-beta isoforms by Roberts, A B, Kondaiah, P, Rosa, F, Watanabe, S, Good, P, Danielpour, D, Roche, N S, Rebbert, M L, Dawid, I B, Sporn, M B

“…Induction of mesoderm in ectodermal explants of Xenopus laevis blastula embryos had previously been shown to respond selectively to TGF-beta 2, with TGF-beta s…”
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Isolation and characterization of TGF-beta 2 and TGF-beta 5 from medium conditioned by Xenopus XTC cells by Roberts, A B, Rosa, F, Roche, N S, Coligan, J E, Garfield, M, Rebbert, M L, Kondaiah, P, Danielpour, D, Kehrl, J H, Wahl, S M

“…TGF-beta 2 and -beta 5 have been purified from medium conditioned by Xenopus cultured cells (XTC) and identified based on their N-terminal amino acid sequence…”
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Differential Responsiveness of myc- and ras-Transfected Cells to Growth Factors: Selective Stimulation of myc-Transfected Cells by Epidermal Growth Factor by Stern, David F., Roberts, Anita B., Roche, Nanette S., Sporn, Michael B., Weinberg, Robert A.

“…To identify functional relationships between oncogenes and growth factors, we compared the effects of transfected myc and ras oncogenes on the responsiveness…”
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Selective loss of the transforming growth factor-β apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells by LARISCH-BLOCH, S, DANIELPOUR, D, ROCHE, N. S, LOTAN, R, HSING, A. Y, KERNER, H, HAJOUJ, T, LECHLEIDER, R. J, ROBERTS, A. B

“…Retroviral insertional mutagenesis was used to select mutant NRP-154 rat prostate carcinoma cells resistant to transforming growth factor (TGF)-beta-induced…”
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