Search Results - "Roche, Kevin C."
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SNIP1 Is a Candidate Modifier of the Transcriptional Activity of c-Myc on E Box-Dependent Target Genes
Published in Molecular cell (08-12-2006)“…Using a yeast two-hybrid screen, we found that SNIP1 (Smad nuclear-interacting protein 1) associates with c-Myc, a key regulator of cell proliferation and…”
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The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro
Published in BMC molecular biology (11-09-2003)“…Pifithrin-alpha is a small molecule inhibitor of p53 transcriptional activity. It has been proposed that the use of pifithrin-alpha in conjunction with…”
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The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression
Published in Oncogene (28-10-2004)“…Smad nuclear interacting protein 1 (SNIP1) is an evolutionarily conserved protein containing a forkhead-associated (FHA) domain that regulates gene expression…”
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An investigation into 53BP1 complex formation
Published in Advances in experimental medicine and biology (2007)“…Loss of the control over cellular proliferation can lead to cell death or result in the abnormal proliferation characteristic of the cancerous state. Among the…”
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The p53-inhibitor Pifithrin-a inhibits Firefly Luciferase activity in vivo and in vitro
Published in BMC molecular biology (01-01-2003)“…Pifithrin-a is a small molecule inhibitor of p53 transcriptional activity. It has been proposed that the use of pifithrin-a in conjunction with…”
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