Search Results - "Roche, Kevin C."

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    The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro by Rocha, Sonia, Campbell, Kirsteen J, Roche, Kevin C, Perkins, Neil D

    Published in BMC molecular biology (11-09-2003)
    “…Pifithrin-alpha is a small molecule inhibitor of p53 transcriptional activity. It has been proposed that the use of pifithrin-alpha in conjunction with…”
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    Journal Article
  3. 3

    The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression by ROCHE, Kevin C, WIECHENS, Nicola, OWEN-HUGHES, Tom, PERKINS, Neil D

    Published in Oncogene (28-10-2004)
    “…Smad nuclear interacting protein 1 (SNIP1) is an evolutionarily conserved protein containing a forkhead-associated (FHA) domain that regulates gene expression…”
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    An investigation into 53BP1 complex formation by Roche, Kevin C, Lowndes, Noel F

    “…Loss of the control over cellular proliferation can lead to cell death or result in the abnormal proliferation characteristic of the cancerous state. Among the…”
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    The p53-inhibitor Pifithrin-a inhibits Firefly Luciferase activity in vivo and in vitro by Rocha, Sonia, Campbell, Kirsteen J, Roche, Kevin C, Perkins, Neil D

    Published in BMC molecular biology (01-01-2003)
    “…Pifithrin-a is a small molecule inhibitor of p53 transcriptional activity. It has been proposed that the use of pifithrin-a in conjunction with…”
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    Journal Article