Search Results - "Roche, James K."

Enteroaggregative Escherichia coli (EAEC) Impairs Growth while Malnutrition Worsens EAEC Infection: A Novel Murine Model of the Infection Malnutrition Cycle by Roche, James K., Cabel, Ace, Sevilleja, Jesus, Nataro, James, Guerrant, Richard L.

“…Background. Enteroaggregative Escherichia coli is emerging as an increasingly recognized cause of persistent, mildly inflammatory diarrhea in the United…”
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Novel In Vitro and In Vivo Models and Potential New Therapeutics to Break the Vicious Cycle of Cryptosporidium Infection and Malnutrition by Costa, Lourrany B., Noronha, Francisco Jose, Roche, James K., Sevilleja, Jesus Emmanuel, Warren, Cirle A., Oriá, Reinaldo, Lima, Aldo, Guerrant, Richard L.

“…Background. Although several animal models of cryptosporidiosis have been reported, most involve genetically or pharmacologically immune-suppressed hosts…”
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Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished mice by Azevedo, Orleâncio G R, Bolick, David T, Roche, James K, Pinkerton, Relana F, Lima, Aldo A M, Vitek, Michael P, Warren, Cirle A, Oriá, Reinaldo B, Guerrant, Richard L

“…Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection…”
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Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile by Viladomiu, Monica, Hontecillas, Raquel, Pedragosa, Mireia, Carbo, Adria, Hoops, Stefan, Michalak, Pawel, Michalak, Katarzyna, Guerrant, Richard L, Roche, James K, Warren, Cirle A, Bassaganya-Riera, Josep

“…Clostridium difficile is an anaerobic bacterium that has re-emerged as a facultative pathogen and can cause nosocomial diarrhea, colitis or even death…”
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Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model by Bartelt, Luther A, Bolick, David T, Kolling, Glynis L, Roche, James K, Zaenker, Edna I, Lara, Ana M, Noronha, Francisco Jose, Cowardin, Carrie A, Moore, John H, Turner, Jerrold R, Warren, Cirle A, Buck, Gregory A, Guerrant, Richard L

“…Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates…”
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The role of peroxisome proliferator-activated receptor γ in immune responses to enteroaggregative Escherichia coli infection by Philipson, Casandra W, Bassaganya-Riera, Josep, Viladomiu, Monica, Pedragosa, Mireia, Guerrant, Richard L, Roche, James K, Hontecillas, Raquel

“…Enteroaggregative Escherichia coli (EAEC) is recognized as an emerging cause of persistent diarrhea and enteric disease worldwide. Mucosal immunity towards…”
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CXCL1/KC and CXCL2/MIP-2 Are Critical Effectors and Potential Targets for Therapy of Escherichia coli O157:H7-Associated Renal Inflammation by Roche, James K, Keepers, Tiffany R, Gross, Lisa K, Seaner, Regina M, Obrig, Tom G

“…Neutrophilia is a characteristic of hemolytic uremic syndrome caused by Shiga toxin (Stx2)-producing Escherichia coli . However, the role of neutrophils in the…”
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Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model by Roche, James K, Stone, Matthew K, Gross, Lisa K, Lindner, Matthew, Seaner, Regina, Pincus, Seth H, Obrig, Tom G

“…Effects in the liver of fatal intoxication with the binary toxin ricin are unclear. We report a robust neutrophil influx into the liver of C57BL/6 mice after…”
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Decreased abundance of trefoil factor 1 transcript in the majority of gastric carcinomas by Beckler, Andrew D., Roche, James K., Harper, Jeffrey C., Petroni, Gina, Frierson, Henry F., Moskaluk, Christopher A., El‐Rifai, Wa'el, Powell, Steven M.

“…BACKGROUND Gastric carcinoma is one of the leading causes of cancer‐related death worldwide, but the mechanisms underlying its development and progression…”
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Pediatric Diarrhea in Southern Ghana: Etiology and Association with Intestinal Inflammation and Malnutrition by OPINTAN, Japheth A, NEWMAN, Mercy J, AYEH-KUMI, Patrick F, AFFRIM, Raymond, GEPI-ATTEE, Rosina, SEVILLEJA, Jesus E. A. D, ROCHE, James K, NATARO, James P, WARREN, Cirle A, GUERRANT, Richard L

“…Diarrhea is a major public health problem that affects the development of children. Anthropometric data were collected from 274 children with (N = 170) and…”
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Enteroaggregative Escherichia coli strain in a novel weaned mouse model: exacerbation by malnutrition, biofilm as a virulence factor and treatment by nitazoxanide by BOLICK, David T, ROCHE, James K, HONTECILLAS, Raquel, BASSAGANYA-RIERA, Josep, NATARO, James P, GUERRANT, Richard L

“…Enteroaggregative Escherichia coli (EAEC) is increasingly recognized as a common cause of diarrhoea in healthy, malnourished and immune-deficient adults and…”
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Prostanoids in human colonic mucosa: effects of inflammation on PGE2 receptor expression by Cosme, Rosana, Lublin, Darienne, Takafuji, Vivian, Lynch, Kevin, Roche, James K

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Intranasal vaccination in mice with an attenuated Salmonella enterica Serovar 908htr A expressing Cp15 of Cryptosporidium : Impact of malnutrition with preservation of cytokine secretion by Roche, James K, Rojo, Ana Lara, Costa, Lourrany B, Smeltz, Ronald, Manque, Patricio, Woehlbier, Ute, Bartelt, Luther, Galen, James, Buck, Gregory, Guerrant, Richard L

“…Abstract Cryptosporidium is a protozoan parasite associated with acute and persistent diarrhea that, even in asymptomatic persons, can impair normal growth and…”
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Transforming Growth Factor β1 Ameliorates Intestinal Epithelial Barrier Disruption by Cryptosporidium parvum In Vitro in the Absence of Mucosal T Lymphocytes by ROCHE, James K, MARTINS, Clovis A. P, COSME, Rosana, FAYER, Ronald, GUERRANT, Richard L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The micronutrient zinc inhibits EAEC strain 042 adherence, biofilm formation, virulence gene expression, and epithelial cytokine responses benefiting the infected host by Medeiros, Pedro, Bolick, David T, Roche, James K, Noronha, Francisco, Pinheiro, Caio, Kolling, Glynis L, Lima, Aldo, Guerrant, Richard L

“…Enteroaggregative Escherichia coli (EAEC) is a major pathogen worldwide, associated with diarrheal disease in both children and adults, suggesting the need for…”
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Cryptosporidium-Malnutrition Interactions: Mucosal Disruption, Cytokines, and TLR Signaling In A Weaned Murine Model by Costa, Lourrany B, JohnBull, Eric A, Reeves, Jordan T, Sevilleja, Jesus Emmanuel, Freire, Rosemayre S, Hoffman, Paul S, Lima, Aldo A. M, Oriá, Reinaldo B, Roche, James K, Guerrant, Richard L, Warren, Cirle Alcantara

“…Cryptosporidiosis is a leading cause of persistent diarrhea in children in impoverished and developing countries and has both a short- and long-term impact on…”
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Ethics Environment in Long-Term Care by McDaniel, Charlotte, Roche, James K., Veledar, Emir

“…This study assesses three hypotheses regarding a long-term care facility’s ethics environment and the relationships between ethics environment, employees’ work…”
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Peri-epithelial origin of prostanoids in the human colon by McCarn, Kate, Yursik, Brenna, Halim, Sharif, Roche, James K.

“…The biology of prostanoids in the normal human colon is only beginning to be understood. We used in situ and in vitro techniques to define the lineage, number,…”
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Magnetic resonance imaging of gastric cancer in Tff1 knock-out mice by Berr, Stuart S., Roche, James K., El-Rifai, Wa'el, Smith Jr, Michael F., Powell, Steven M.

“…In this work, the use of MRI to stage gastric neoplasia in a mouse model of spontaneous gastric cancer is demonstrated. The methodology involves 1) the use of…”
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Mucosal prostanoid receptors and synthesis in familial adenomatous polyposis by Takafuji, V, Lublin, D, Lynch, K, Roche, J K

“…Chronic ingestion of non-steroidal anti-inflammatory medication is reported to delay or, in part, reverse development of polyps in the colon, but the mechanism…”
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